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The map label for this gene is rnhA [H]

Identifier: 195953035

GI number: 195953035

Start: 591507

End: 591968

Strand: Direct

Name: rnhA [H]

Synonym: HY04AAS1_0660

Alternate gene names: 195953035

Gene position: 591507-591968 (Clockwise)

Preceding gene: 195953034

Following gene: 195953046

Centisome position: 37.93

GC content: 33.77

Gene sequence:

>462_bases
ATGGAAATAAAGATATACACGGACGGAAGTTGTTTGGGAAACCCAGGAGCAGGTGGTTACTGTGCCATATTAAAAGCCAT
AAAAAATGGCAAAGTAGTAAAAGAAAAGATAATAAAGGGTACTGAGGCAAACACCACCAACAACCGAATGGAACTAAAAG
CTGTAATAGAGGCTTTAAAAGCTTTAAGTAAAAAAGACCAAAAAATAACCATATATACAGATAGCCAATACGTGGCAAAC
GGCATAAAGCTATGGCTAAATAATTGGATTAAAAAGGATTTTAAAGGCATAAAAAACGAAGATTTATGGAAAGAGCTTTA
CGAGCTTTTAAAAAATCAAAATATAGAAGTAGTGTGGTTAAGAGGGCATCAAAAGAACAAAGGAGATGATCATGACACAA
ACAATTTATGTGATAAAATAGCAAAAGAAGAGGCTATGAAGGTAATAAAAGAGACCTCATGA

Upstream 100 bases:

>100_bases
AAAATGGAAACGTGAAGTTTCTTGATAAAGCAATAAAGCTAGCAGAAAAATTCAACACTAGAATAATACCACAAATGCAC
AAACTTTTAGGTTTAAAATA

Downstream 100 bases:

>100_bases
AAGCTTCAGCGTATTCTACAGGCTCCCCTGGTTTTTGTATATATATATCAAAATGTTCTTTGTAAAGATAGGGAAAATCT
TTTACGTTTTCAAAATAATG

Product: Ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MEIKIYTDGSCLGNPGAGGYCAILKAIKNGKVVKEKIIKGTEANTTNNRMELKAVIEALKALSKKDQKITIYTDSQYVAN
GIKLWLNNWIKKDFKGIKNEDLWKELYELLKNQNIEVVWLRGHQKNKGDDHDTNNLCDKIAKEEAMKVIKETS

Sequences:

>Translated_153_residues
MEIKIYTDGSCLGNPGAGGYCAILKAIKNGKVVKEKIIKGTEANTTNNRMELKAVIEALKALSKKDQKITIYTDSQYVAN
GIKLWLNNWIKKDFKGIKNEDLWKELYELLKNQNIEVVWLRGHQKNKGDDHDTNNLCDKIAKEEAMKVIKETS
>Mature_153_residues
MEIKIYTDGSCLGNPGAGGYCAILKAIKNGKVVKEKIIKGTEANTTNNRMELKAVIEALKALSKKDQKITIYTDSQYVAN
GIKLWLNNWIKKDFKGIKNEDLWKELYELLKNQNIEVVWLRGHQKNKGDDHDTNNLCDKIAKEEAMKVIKETS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=150, Percent_Identity=44, Blast_Score=116, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17137476, Length=147, Percent_Identity=39.4557823129252, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45552509, Length=147, Percent_Identity=39.4557823129252, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 17370; Mature: 17370

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKIYTDGSCLGNPGAGGYCAILKAIKNGKVVKEKIIKGTEANTTNNRMELKAVIEALK
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ALSKKDQKITIYTDSQYVANGIKLWLNNWIKKDFKGIKNEDLWKELYELLKNQNIEVVWL
HHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEE
RGHQKNKGDDHDTNNLCDKIAKEEAMKVIKETS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIKIYTDGSCLGNPGAGGYCAILKAIKNGKVVKEKIIKGTEANTTNNRMELKAVIEALK
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ALSKKDQKITIYTDSQYVANGIKLWLNNWIKKDFKGIKNEDLWKELYELLKNQNIEVVWL
HHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEE
RGHQKNKGDDHDTNNLCDKIAKEEAMKVIKETS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA