Click here to switch to the map view.

The map label for this gene is acuC [H]

Identifier: 195953018

GI number: 195953018

Start: 577118

End: 578257

Strand: Direct

Name: acuC [H]

Synonym: HY04AAS1_0643

Alternate gene names: 195953018

Gene position: 577118-578257 (Clockwise)

Preceding gene: 195953017

Following gene: 195953019

Centisome position: 37.01

GC content: 33.25

Gene sequence:

>1140_bases
GTGAATATTTTAATAGCTAGTGAAAAGTATAAAGAACTAAGATATCCTAAAAACCATCCCTTGAGGGTGCCTAGGGTTTC
CCTTATGATAAATTACCTTAAGGCACTTGGTTTTGATGTTGATTATCTAGAAGGAAGGGATGCGTCTATAGAAGAGTTGC
TTATTTTCCACACAAAAGATTATATAGACGCTCTTATAGAAGCAGATAGAATGATGAAAGCAACCAATTATATAAGAGAA
AAATATGCCATAGGAACTATAGAAAATCCTGTATCAGCGGGCATGTGGAAAGGATCTTTATTGGCAACTGGCTCTAGCGT
CCAAGCCGTAGAATTTTATATTAAAAACTATAAAACAGAGAATGAAATTGTAGCATTTAATCCAGCAGGTGGAATGCATC
ACGCAATGAAATCACGGGCAAACGGTTTTTGTTTTTTAAACGATCCAGTTATAAGCATATTGCATCTACAAAAACATGGT
TTTAAGAAGATAATGTATATAGATTTAGATGCTCATCATCCAGATGGTGTTCAAGAAGCTTTTTATAACAGCGCCGATGT
GTTTTTAATAAGCTTGCATCAATCTCCAGAGTATGCTTTTCCTTTCCATGTTGGATATGCAGATGAACTAGGAGAAGGTG
AAGGTTTTGGTTTTAATATGAATATACCTCTTCCAAAGGAGATTAACGATAACGATTTCTTGCATGCTTTAGAAAAAGCC
ATTGAAATAGCCACAAAAAAATTTACCCCGGATGTTTTTGTAGTGCAAATGGGTGTTGATGCTGTAAAAGAAGATTATCT
ATCGAAATTCAATCTATCAAACAACATTTATATAAAAGCAATAGATATTATAAAACAATACACAAAAAAATTTATATTGC
TTGGAGGCGGTGGATACAATCCAATAAGCCTTGCCAGAGCATGGTCTTTAATATGGCTTCATTTAGAAGGTATCGATGTA
AAATCTATAAAAGTTACAAAAGAAGCAAAAATGCTTTTAGAATCTATAGATTATGAAGATTTTGACGAGATCATGGAACC
ACAAATATATACCAGCATACTCGATGAACCACGAGGGGGAGATATTACCATAAAAGAATATCTTGAAAAAATATTTTCTT
TGCATAAATTTAATATATGA

Upstream 100 bases:

>100_bases
GGCATGGATGGTAAAATGCACCCAGGAGCCCCAAGTAGTGAAAAACAGTTAGACCAATGGTTAGGTAAATAAATCATTTT
ATTTTTAGGCTTTTTACAGT

Downstream 100 bases:

>100_bases
TGGTATAATCATATGGTTATATCACTAATTTATATTATTTTTGGAGGTATGTATGGAAACAATGGAAAAGCCTAAGAGCA
CCATAGATCAGAAAATAAAG

Product: histone deacetylase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNILIASEKYKELRYPKNHPLRVPRVSLMINYLKALGFDVDYLEGRDASIEELLIFHTKDYIDALIEADRMMKATNYIRE
KYAIGTIENPVSAGMWKGSLLATGSSVQAVEFYIKNYKTENEIVAFNPAGGMHHAMKSRANGFCFLNDPVISILHLQKHG
FKKIMYIDLDAHHPDGVQEAFYNSADVFLISLHQSPEYAFPFHVGYADELGEGEGFGFNMNIPLPKEINDNDFLHALEKA
IEIATKKFTPDVFVVQMGVDAVKEDYLSKFNLSNNIYIKAIDIIKQYTKKFILLGGGGYNPISLARAWSLIWLHLEGIDV
KSIKVTKEAKMLLESIDYEDFDEIMEPQIYTSILDEPRGGDITIKEYLEKIFSLHKFNI

Sequences:

>Translated_379_residues
MNILIASEKYKELRYPKNHPLRVPRVSLMINYLKALGFDVDYLEGRDASIEELLIFHTKDYIDALIEADRMMKATNYIRE
KYAIGTIENPVSAGMWKGSLLATGSSVQAVEFYIKNYKTENEIVAFNPAGGMHHAMKSRANGFCFLNDPVISILHLQKHG
FKKIMYIDLDAHHPDGVQEAFYNSADVFLISLHQSPEYAFPFHVGYADELGEGEGFGFNMNIPLPKEINDNDFLHALEKA
IEIATKKFTPDVFVVQMGVDAVKEDYLSKFNLSNNIYIKAIDIIKQYTKKFILLGGGGYNPISLARAWSLIWLHLEGIDV
KSIKVTKEAKMLLESIDYEDFDEIMEPQIYTSILDEPRGGDITIKEYLEKIFSLHKFNI
>Mature_379_residues
MNILIASEKYKELRYPKNHPLRVPRVSLMINYLKALGFDVDYLEGRDASIEELLIFHTKDYIDALIEADRMMKATNYIRE
KYAIGTIENPVSAGMWKGSLLATGSSVQAVEFYIKNYKTENEIVAFNPAGGMHHAMKSRANGFCFLNDPVISILHLQKHG
FKKIMYIDLDAHHPDGVQEAFYNSADVFLISLHQSPEYAFPFHVGYADELGEGEGFGFNMNIPLPKEINDNDFLHALEKA
IEIATKKFTPDVFVVQMGVDAVKEDYLSKFNLSNNIYIKAIDIIKQYTKKFILLGGGGYNPISLARAWSLIWLHLEGIDV
KSIKVTKEAKMLLESIDYEDFDEIMEPQIYTSILDEPRGGDITIKEYLEKIFSLHKFNI

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=299, Percent_Identity=34.1137123745819, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI13128862, Length=305, Percent_Identity=33.1147540983607, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI8923769, Length=293, Percent_Identity=31.0580204778157, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI293336691, Length=299, Percent_Identity=32.7759197324415, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI262073088, Length=220, Percent_Identity=32.2727272727273, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI262073092, Length=221, Percent_Identity=31.2217194570136, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI153085395, Length=306, Percent_Identity=28.4313725490196, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169234807, Length=273, Percent_Identity=28.9377289377289, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI148539870, Length=273, Percent_Identity=28.9377289377289, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI20070354, Length=309, Percent_Identity=25.8899676375405, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI17158039, Length=269, Percent_Identity=28.2527881040892, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI30795202, Length=269, Percent_Identity=28.2527881040892, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI30795204, Length=269, Percent_Identity=28.2527881040892, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI13128864, Length=303, Percent_Identity=27.7227722772277, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226529806, Length=253, Percent_Identity=28.0632411067194, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI62750349, Length=360, Percent_Identity=27.2222222222222, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI62750347, Length=360, Percent_Identity=27.2222222222222, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI217272877, Length=302, Percent_Identity=23.841059602649, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508561, Length=300, Percent_Identity=34.6666666666667, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17534739, Length=302, Percent_Identity=36.4238410596026, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17561978, Length=329, Percent_Identity=31.0030395136778, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=26.4705882352941, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17540332, Length=301, Percent_Identity=26.9102990033223, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193206283, Length=301, Percent_Identity=26.9102990033223, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193209491, Length=291, Percent_Identity=25.085910652921, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=338, Percent_Identity=24.8520710059172, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25154022, Length=275, Percent_Identity=23.2727272727273, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25154020, Length=275, Percent_Identity=22.9090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=307, Percent_Identity=32.5732899022801, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323999, Length=304, Percent_Identity=32.8947368421053, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6324307, Length=270, Percent_Identity=26.6666666666667, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325325, Length=195, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24657891, Length=299, Percent_Identity=33.4448160535117, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644244, Length=373, Percent_Identity=29.4906166219839, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24642146, Length=229, Percent_Identity=30.1310043668122, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360899, Length=310, Percent_Identity=26.7741935483871, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24642142, Length=330, Percent_Identity=26.0606060606061, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24642144, Length=330, Percent_Identity=26.0606060606061, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641720, Length=247, Percent_Identity=29.1497975708502, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360801, Length=247, Percent_Identity=29.1497975708502, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360799, Length=247, Percent_Identity=29.1497975708502, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 43213; Mature: 43213

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILIASEKYKELRYPKNHPLRVPRVSLMINYLKALGFDVDYLEGRDASIEELLIFHTKD
CEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHEEEHHHH
YIDALIEADRMMKATNYIREKYAIGTIENPVSAGMWKGSLLATGSSVQAVEFYIKNYKTE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEECCCCHHHHHHHHHHCCCC
NEIVAFNPAGGMHHAMKSRANGFCFLNDPVISILHLQKHGFKKIMYIDLDAHHPDGVQEA
CCEEEECCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHH
FYNSADVFLISLHQSPEYAFPFHVGYADELGEGEGFGFNMNIPLPKEINDNDFLHALEKA
HCCCCCEEEEEEECCCCCCCEEECCCHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHH
IEIATKKFTPDVFVVQMGVDAVKEDYLSKFNLSNNIYIKAIDIIKQYTKKFILLGGGGYN
HHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHEEEEECCCCCC
PISLARAWSLIWLHLEGIDVKSIKVTKEAKMLLESIDYEDFDEIMEPQIYTSILDEPRGG
HHHHHHHEEEEEEEEECCCEEEEEEHHHHHHHHHHCCCCCHHHHHCCHHHHHHHCCCCCC
DITIKEYLEKIFSLHKFNI
CEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILIASEKYKELRYPKNHPLRVPRVSLMINYLKALGFDVDYLEGRDASIEELLIFHTKD
CEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHEEEHHHH
YIDALIEADRMMKATNYIREKYAIGTIENPVSAGMWKGSLLATGSSVQAVEFYIKNYKTE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCEEECCCCHHHHHHHHHHCCCC
NEIVAFNPAGGMHHAMKSRANGFCFLNDPVISILHLQKHGFKKIMYIDLDAHHPDGVQEA
CCEEEECCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHH
FYNSADVFLISLHQSPEYAFPFHVGYADELGEGEGFGFNMNIPLPKEINDNDFLHALEKA
HCCCCCEEEEEEECCCCCCCEEECCCHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHH
IEIATKKFTPDVFVVQMGVDAVKEDYLSKFNLSNNIYIKAIDIIKQYTKKFILLGGGGYN
HHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHEEEEECCCCCC
PISLARAWSLIWLHLEGIDVKSIKVTKEAKMLLESIDYEDFDEIMEPQIYTSILDEPRGG
HHHHHHHEEEEEEEEECCCEEEEEEHHHHHHHHHHCCCCCHHHHHCCHHHHHHHCCCCCC
DITIKEYLEKIFSLHKFNI
CEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]