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The map label for this gene is purQ [H]

Identifier: 195952934

GI number: 195952934

Start: 495014

End: 495673

Strand: Direct

Name: purQ [H]

Synonym: HY04AAS1_0559

Alternate gene names: 195952934

Gene position: 495014-495673 (Clockwise)

Preceding gene: 195952933

Following gene: 195952935

Centisome position: 31.74

GC content: 38.79

Gene sequence:

>660_bases
ATGATGAAAATAGGTATTTGCGTGTTTCCGGGTTCTAACTGCGATTACGATACTTACTATATAGTAAAAGACATTTTACA
AGAAGACGCAGAGTTAATTGATTATACCGTTGGAGATTTGGAGCGCTTTGACGCCGTTATATTACCAGGAGGGTTTTCTT
TCGGAGATTATTTAAGACCGGGGGCTTTAGCTTCCAAAACACCTCTGGCAGAAGCCATAGTAAACTTTGCAGCGAAAGGT
AGATATGTGCTTGGTATATGCAACGGATTCCAAATTTTAACAGAGTTAAGACTCTTGCCTGGAGCACTTCTTCCAAACGA
AAACGATAGATTTATATGCAAAAGGGTAAATATATCAGTAGAAAATATTTCTACAGCTTTTACAAAAGAATTAGAAGAAA
AGGAGACAATAGTGCTACCCATAGCTCACCACGATGGTAGATTTTATGCGCCTGAAGATGTGTTGGAAGAAATTGAGAAG
AATAACCAAGTGGTGTTTAGATACGAAGGAGAAAATCCAAACGGTTCTTTGAATTCCATCGCTGGGGTGTGCAACAAAAC
TGGTAACGTAGTAGGTATGATGCCTCATCCTGAGCGTATATCCGAAGATATTTTAGGTGGTTTGGATGGCCTAAAAATTT
GGCATTCTCTTATAGCCTAA

Upstream 100 bases:

>100_bases
TAGGGAAAATAATAGAAATAGAAGCTGATTCACTTGAAAATCTACAAAAGATGATTGAAGATTATATTATAAATCCACTT
ATTGAAGATTACGAAGTGCT

Downstream 100 bases:

>100_bases
CTTAAAGGAGGCAATATGGATTTAGAAACCCAAAACATTTACGTAAATCAAGAAATTCAAAAGTTAAATTTGATGCCGCT
AAGAGATATTATAGTATTTC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MMKIGICVFPGSNCDYDTYYIVKDILQEDAELIDYTVGDLERFDAVILPGGFSFGDYLRPGALASKTPLAEAIVNFAAKG
RYVLGICNGFQILTELRLLPGALLPNENDRFICKRVNISVENISTAFTKELEEKETIVLPIAHHDGRFYAPEDVLEEIEK
NNQVVFRYEGENPNGSLNSIAGVCNKTGNVVGMMPHPERISEDILGGLDGLKIWHSLIA

Sequences:

>Translated_219_residues
MMKIGICVFPGSNCDYDTYYIVKDILQEDAELIDYTVGDLERFDAVILPGGFSFGDYLRPGALASKTPLAEAIVNFAAKG
RYVLGICNGFQILTELRLLPGALLPNENDRFICKRVNISVENISTAFTKELEEKETIVLPIAHHDGRFYAPEDVLEEIEK
NNQVVFRYEGENPNGSLNSIAGVCNKTGNVVGMMPHPERISEDILGGLDGLKIWHSLIA
>Mature_219_residues
MMKIGICVFPGSNCDYDTYYIVKDILQEDAELIDYTVGDLERFDAVILPGGFSFGDYLRPGALASKTPLAEAIVNFAAKG
RYVLGICNGFQILTELRLLPGALLPNENDRFICKRVNISVENISTAFTKELEEKETIVLPIAHHDGRFYAPEDVLEEIEK
NNQVVFRYEGENPNGSLNSIAGVCNKTGNVVGMMPHPERISEDILGGLDGLKIWHSLIA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=199, Percent_Identity=33.1658291457286, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=205, Percent_Identity=29.2682926829268, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582111, Length=214, Percent_Identity=28.5046728971963, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582109, Length=214, Percent_Identity=28.5046728971963, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137292, Length=214, Percent_Identity=28.5046728971963, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24226; Mature: 24226

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKIGICVFPGSNCDYDTYYIVKDILQEDAELIDYTVGDLERFDAVILPGGFSFGDYLRP
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHCCC
GALASKTPLAEAIVNFAAKGRYVLGICNGFQILTELRLLPGALLPNENDRFICKRVNISV
CCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEEEEEECEEH
ENISTAFTKELEEKETIVLPIAHHDGRFYAPEDVLEEIEKNNQVVFRYEGENPNGSLNSI
HHHHHHHHHHHCCCCEEEEEEEECCCCEECHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
AGVCNKTGNVVGMMPHPERISEDILGGLDGLKIWHSLIA
HHHHCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHC
>Mature Secondary Structure
MMKIGICVFPGSNCDYDTYYIVKDILQEDAELIDYTVGDLERFDAVILPGGFSFGDYLRP
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHCCC
GALASKTPLAEAIVNFAAKGRYVLGICNGFQILTELRLLPGALLPNENDRFICKRVNISV
CCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEEEEEECEEH
ENISTAFTKELEEKETIVLPIAHHDGRFYAPEDVLEEIEKNNQVVFRYEGENPNGSLNSI
HHHHHHHHHHHCCCCEEEEEEEECCCCEECHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
AGVCNKTGNVVGMMPHPERISEDILGGLDGLKIWHSLIA
HHHHCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]