Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 195952525

GI number: 195952525

Start: 129937

End: 130950

Strand: Direct

Name: trpD [H]

Synonym: HY04AAS1_0145

Alternate gene names: 195952525

Gene position: 129937-130950 (Clockwise)

Preceding gene: 195952524

Following gene: 195952526

Centisome position: 8.33

GC content: 34.32

Gene sequence:

>1014_bases
ATGATAGATGTTCTTTCTAAATTATCGATAAAGGAAAATCTAACAAAAGAAGATATAAGACAAATGTTAGAATCCATTGC
TTCAAACGAAGCCACAGAAGCTCAAATGGGCGCTTTCATAATGGGGATGAGATTAAAGGGAGAAACAATAGAAGAGATAA
CAGAGATAGCAAAGTTTTTTAGAGAAAAAGCTTTAAAAGTCCCAGTAAACAATCAAGAAGAACTTTTAGATACTTGTGGG
ACTGGCGGAGATGGAAAATCCACCTTCAACATATCAACGGCTAGTGCATTTGTTATAGCTGGTGCTGGTTTTAAAGTGGC
AAAACATGGCAACAAATCCGTATCTTCAAAGTGTGGAAGTGCTGATATATTAGAACGTCTTGGTGTAAACATAAGTATGT
CGCCAAATCATATAGCAAGATGTATAGAAGAAGTTGGTATTGGATTTATCTATGCACCTTTTCATCATGGTGTTATGAAA
AACATAGCAAAGCCACGAAAAGAACTTGGAATAAAATCTGTTTTCAACCTTGTAGGACCTCTTTCAAATCCCGCTGGTGC
TAAAAGGCAGATAATGGGTGTTTACGATATATATTTGGTGGAGAAAATAGCTTACGTGTTAAAGGAGCTAGGTAACATAA
AATCTTTTGTGTTTAGTAGTTATGATGGTATGGATGAGGTTTCTATAAGCTCCAAAACGCTTGTGGCAAAACAAACAAAA
GACGATGTTGACATGTTTGAATTTGATCCTACAGAGTATGGATTTTCTTTTCAAAATATAGAAGATATCCAAGCCAAAGA
TATAGAAGAAAGCTTAAATTTATTTAATATGGCTTTAAGCGGTAAGCCGTCGGCTGCTCTTGATGTAGTGCTTATAAATG
CTAGTTTTGGTATTATGGCTTTTAGCGATATAGCTTTTAAAGAAGCTTTGGAAATAGCAAAAGATAGTGTGTTTTCTAAA
AAAGCTTTAAATAAGCTACAAAGTTTGATAGAATGTTCAAATTATACTGAATGA

Upstream 100 bases:

>100_bases
AGATGGTTATAGTTCCTGTTTTAAAGGTAGAAGTTGTAGAGGCCAAAGAACTCTCTAATACACAAAGACAAGATGGTGGT
TTTGGTTCCACAGGTATGAA

Downstream 100 bases:

>100_bases
TAAAAGTAGGTAAAGTATCTTATTTAAATACGCTTCCCATGTTTTACAATCTTTTAAATTATGAAATAATAGAAGGACAC
CCTTCAGAGCTTTTTAAAAT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIDVLSKLSIKENLTKEDIRQMLESIASNEATEAQMGAFIMGMRLKGETIEEITEIAKFFREKALKVPVNNQEELLDTCG
TGGDGKSTFNISTASAFVIAGAGFKVAKHGNKSVSSKCGSADILERLGVNISMSPNHIARCIEEVGIGFIYAPFHHGVMK
NIAKPRKELGIKSVFNLVGPLSNPAGAKRQIMGVYDIYLVEKIAYVLKELGNIKSFVFSSYDGMDEVSISSKTLVAKQTK
DDVDMFEFDPTEYGFSFQNIEDIQAKDIEESLNLFNMALSGKPSAALDVVLINASFGIMAFSDIAFKEALEIAKDSVFSK
KALNKLQSLIECSNYTE

Sequences:

>Translated_337_residues
MIDVLSKLSIKENLTKEDIRQMLESIASNEATEAQMGAFIMGMRLKGETIEEITEIAKFFREKALKVPVNNQEELLDTCG
TGGDGKSTFNISTASAFVIAGAGFKVAKHGNKSVSSKCGSADILERLGVNISMSPNHIARCIEEVGIGFIYAPFHHGVMK
NIAKPRKELGIKSVFNLVGPLSNPAGAKRQIMGVYDIYLVEKIAYVLKELGNIKSFVFSSYDGMDEVSISSKTLVAKQTK
DDVDMFEFDPTEYGFSFQNIEDIQAKDIEESLNLFNMALSGKPSAALDVVLINASFGIMAFSDIAFKEALEIAKDSVFSK
KALNKLQSLIECSNYTE
>Mature_337_residues
MIDVLSKLSIKENLTKEDIRQMLESIASNEATEAQMGAFIMGMRLKGETIEEITEIAKFFREKALKVPVNNQEELLDTCG
TGGDGKSTFNISTASAFVIAGAGFKVAKHGNKSVSSKCGSADILERLGVNISMSPNHIARCIEEVGIGFIYAPFHHGVMK
NIAKPRKELGIKSVFNLVGPLSNPAGAKRQIMGVYDIYLVEKIAYVLKELGNIKSFVFSSYDGMDEVSISSKTLVAKQTK
DDVDMFEFDPTEYGFSFQNIEDIQAKDIEESLNLFNMALSGKPSAALDVVLINASFGIMAFSDIAFKEALEIAKDSVFSK
KALNKLQSLIECSNYTE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=279, Percent_Identity=35.1254480286738, Blast_Score=166, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=29.7546012269939, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36881; Mature: 36881

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVLSKLSIKENLTKEDIRQMLESIASNEATEAQMGAFIMGMRLKGETIEEITEIAKFF
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
REKALKVPVNNQEELLDTCGTGGDGKSTFNISTASAFVIAGAGFKVAKHGNKSVSSKCGS
HHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEHHCEEEEECCCEEEHHCCCCHHHHCCCC
ADILERLGVNISMSPNHIARCIEEVGIGFIYAPFHHGVMKNIAKPRKELGIKSVFNLVGP
HHHHHHCCCCEEECHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSNPAGAKRQIMGVYDIYLVEKIAYVLKELGNIKSFVFSSYDGMDEVSISSKTLVAKQTK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHEEECCCC
DDVDMFEFDPTEYGFSFQNIEDIQAKDIEESLNLFNMALSGKPSAALDVVLINASFGIMA
CCCCCEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHH
FSDIAFKEALEIAKDSVFSKKALNKLQSLIECSNYTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIDVLSKLSIKENLTKEDIRQMLESIASNEATEAQMGAFIMGMRLKGETIEEITEIAKFF
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
REKALKVPVNNQEELLDTCGTGGDGKSTFNISTASAFVIAGAGFKVAKHGNKSVSSKCGS
HHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEHHCEEEEECCCEEEHHCCCCHHHHCCCC
ADILERLGVNISMSPNHIARCIEEVGIGFIYAPFHHGVMKNIAKPRKELGIKSVFNLVGP
HHHHHHCCCCEEECHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSNPAGAKRQIMGVYDIYLVEKIAYVLKELGNIKSFVFSSYDGMDEVSISSKTLVAKQTK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHEEECCCC
DDVDMFEFDPTEYGFSFQNIEDIQAKDIEESLNLFNMALSGKPSAALDVVLINASFGIMA
CCCCCEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHH
FSDIAFKEALEIAKDSVFSKKALNKLQSLIECSNYTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]