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The map label for this gene is speH

Identifier: 195952459

GI number: 195952459

Start: 72431

End: 72835

Strand: Direct

Name: speH

Synonym: HY04AAS1_0079

Alternate gene names: 195952459

Gene position: 72431-72835 (Clockwise)

Preceding gene: 195952452

Following gene: 195952460

Centisome position: 4.64

GC content: 40.0

Gene sequence:

>405_bases
ATGGCAAAAACCCTCGGACTCCATATTATAGCTGACCTTTATGGAGTTAACCCTGATCTCATTGACAGGGAAGAAGATAT
CAGACACCTTCTTGAAAATTCAGTAAAAGCAGGAGAGCTTACAAAAATCTCCTCTCATTTTTACCAGTTTAACCCTCACG
GAGCTACGGGAGTTATCCTGTTAGCCGAATCTCATATATCCATTCATACGTGGCCAGAGCATAAAACGGCTACTGTGGAT
GTATTTACCTGTGGAGACCCATCAAAGGCTTATAGAGCCATGGACTATATAATAAACTCTTTATCCCCTACTCACGTAGA
TAAAAAAGTCTTTGATAGAGGTATCATAGAAGATTCAAAGGGAAAAGATGTGCTTTGGATAATGTCGAAAGCTGGTTGTT
GCTAA

Upstream 100 bases:

>100_bases
AGGATAGCAAATTCCGAAAGCGTGTGGGTGGCGCTGGTAATTTTGAGCAAGTTAGTTGCTCCACATCTTTTGTTGTGTTG
ATACCAAGGGAGGTATTGAA

Downstream 100 bases:

>100_bases
AATCCATAAAAGGAATAGGCAACAAGTTACTATATAGGGCTTTTAGACATTTTGGTAGTGCCGAAGCAATATTAAAAGCC
GACAAAACATCTTTGGAGCC

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MAKTLGLHIIADLYGVNPDLIDREEDIRHLLENSVKAGELTKISSHFYQFNPHGATGVILLAESHISIHTWPEHKTATVD
VFTCGDPSKAYRAMDYIINSLSPTHVDKKVFDRGIIEDSKGKDVLWIMSKAGCC

Sequences:

>Translated_134_residues
MAKTLGLHIIADLYGVNPDLIDREEDIRHLLENSVKAGELTKISSHFYQFNPHGATGVILLAESHISIHTWPEHKTATVD
VFTCGDPSKAYRAMDYIINSLSPTHVDKKVFDRGIIEDSKGKDVLWIMSKAGCC
>Mature_133_residues
AKTLGLHIIADLYGVNPDLIDREEDIRHLLENSVKAGELTKISSHFYQFNPHGATGVILLAESHISIHTWPEHKTATVDV
FTCGDPSKAYRAMDYIINSLSPTHVDKKVFDRGIIEDSKGKDVLWIMSKAGCC

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_HYDS0 (B4U6K3)

Other databases:

- EMBL:   CP001130
- RefSeq:   YP_002120749.1
- ProteinModelPortal:   B4U6K3
- SMR:   B4U6K3
- GeneID:   6742862
- GenomeReviews:   CP001130_GR
- KEGG:   hya:HY04AAS1_0079
- HOGENOM:   HBG485559
- OMA:   KPNEMHI
- ProtClustDB:   PRK01236
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 14920; Mature: 14789

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: ACT_SITE 64-64 ACT_SITE 69-69 ACT_SITE 84-84

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTLGLHIIADLYGVNPDLIDREEDIRHLLENSVKAGELTKISSHFYQFNPHGATGVIL
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEEECCCCCCEEEE
LAESHISIHTWPEHKTATVDVFTCGDPSKAYRAMDYIINSLSPTHVDKKVFDRGIIEDSK
EECCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
GKDVLWIMSKAGCC
CCEEEEEECCCCCC
>Mature Secondary Structure 
AKTLGLHIIADLYGVNPDLIDREEDIRHLLENSVKAGELTKISSHFYQFNPHGATGVIL
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEEECCCCCCEEEE
LAESHISIHTWPEHKTATVDVFTCGDPSKAYRAMDYIINSLSPTHVDKKVFDRGIIEDSK
EECCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
GKDVLWIMSKAGCC
CCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA