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The map label for this gene is ntrY [H]

Identifier: 195952393

GI number: 195952393

Start: 12459

End: 14255

Strand: Direct

Name: ntrY [H]

Synonym: HY04AAS1_0013

Alternate gene names: 195952393

Gene position: 12459-14255 (Clockwise)

Preceding gene: 195952392

Following gene: 195952396

Centisome position: 0.8

GC content: 32.33

Gene sequence:

>1797_bases
GTGAGATGGTTAAACATAAACACATTCAAGAAAAAAGTTAATTTAGTTTTAGGGCTTTTAGCATTATCAATAGTCTTAAC
CTCAAATATAGGTTTTGTACTAAATTTAAAACATAACCCCTCTATAAATATATACGCTTTTCTTGCTATCATCAATATAA
ACCTTTTTGCTCTTTTACTGGCTAGTGTTATAATATTTAGAAAATTTATAAAATTATATTACGAAACCAAGAAAAAAACC
TTACGTACAAAAATAACCACCATAATACTCCTTTATATGTTTTTACCAATATCTCTTATGATGTTTGCATCAAGCTTTGT
GATAGTAGAAAGCGTTAAAACCTTTATAAGCGATAAGACCAAGCTTGTTTTAAGAACATCTATAAAACTTTCCAAAGAGA
TCGAACAAAGCCAATATGAAAAAGCTATTCTTTATAGAAATTTTTTGAGTAGGTTGGTTTTTTATGAAGACCCTTATTCT
CTTGTAAATCATTTTGATATAAGGGCTGTGCACGAAGTATCTGATTGCGACAATCCCATTGTAGAAAATCAAAAATCTTA
CAGCATATGTATAATGAAAGGAGACAAAGCGTATGTATTTGTGGTAGGTAAAGATGCTAAGCTTGAAAAATCTTCAAAAG
CCTTAAACCGCTTTGCCAAAGAGTTTATTGTGCTTGTAAAAACAAGAGATATCTTAAATGGAAACTACGTTGCTTTTATC
GTGATATTGGCTCTTATGGTGGTGCTTTTTACCGTTTGGTTTGGTATATTTTTAGCCCGTCATATATCAGAGCCCATTGA
AGAACTATCGGAAGCTGCTAAAACTTTGGCAAAAGGTGACCTCGATACAAAACTACCAACTCCACGAACCAACGACGAAT
TATCAGAACTAATACAAGCTTTTCAATATATGAAAGAAAACCTTAAAAAGCTCTATCAAGACCTTATAAAAGAAAAAGAC
CAGCTAAATAAACTCCTTGACAACATACCGATAGGTGTAGCTTACGTAGACAAAGACTACAATGTAATAAGAGTAAACAA
AGCATTTTTAGATATGTTTGGAAACACCGATATAAAAAATTTAGATTTTAAAGATAAAAACATAAGACAAGATATAATAG
AACTCTCAGAAAACGAAAAAATCTTTATCTTTGAAGATGTAAGCCCTATGGTAAACGCTCAAAGGCTTTCTGTTTGGAAA
GAAACCGCCCAAAGAGTAGCCCACGAGCTAAAAAACCCCCTTACCCCTATAAAACTAAACATAGAAAGGCTTCTTAGAAT
ATCAAAAAATCATCCAGAAAAACTCCAAGATACCATAAACGCCGTAGGAGATATAGTCTTAAAAGAAATAGACAAGATAT
TAAAACTTCTTCAAGATTTTAAAGACTTTTCAAATATAGAAATACTTGATAAATCTACTCAATCTATAAAAGATGCAATC
TTAGAAGCAATAGAGCTTTACAAACCCTATAGCGTAGATTTTGAGATAATAGGAGACAATATTTTGGAGTTTGACAAAGA
AAAGATAAAGATCGTGTTTATGAACCTCATCCAAAACAGCATAGAATCTAAAAGCACCAAGATAAAAATAGAGATAAAAC
CAAAGGAGATTATATACCAAGACAACGGCGAGGGTATAAAAGAAATATCCAAAATCTTCTTGCCTTATTATTCTAGCAAA
CCCACTGGCACAGGTCTTGGTCTTAGCATCGTAAAAGCCATCATACAAAAACATGGCTGGGATATAAAAGCCCTTCCCTC
AAGTGCTGGGGCTTTGTTTGTGATAACTATACCCTAA

Upstream 100 bases:

>100_bases
ATAAAAAGGGCTATATCTTTGGAAATGGTGGCAAGACATTTTGAAAGAATAGCCGATCACGCTGAAAACGTATCAGAGAT
GGCTATATACTTGGTGCAAG

Downstream 100 bases:

>100_bases
CGTATAATTTTTTGTTATACAAATACCAAACTACCGAAAATATGATACTTAAAACACTTTCTATCTTAAAAGCCAAAGAC
AAATTTATAAAATGAGATAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRWLNINTFKKKVNLVLGLLALSIVLTSNIGFVLNLKHNPSINIYAFLAIININLFALLLASVIIFRKFIKLYYETKKKT
LRTKITTIILLYMFLPISLMMFASSFVIVESVKTFISDKTKLVLRTSIKLSKEIEQSQYEKAILYRNFLSRLVFYEDPYS
LVNHFDIRAVHEVSDCDNPIVENQKSYSICIMKGDKAYVFVVGKDAKLEKSSKALNRFAKEFIVLVKTRDILNGNYVAFI
VILALMVVLFTVWFGIFLARHISEPIEELSEAAKTLAKGDLDTKLPTPRTNDELSELIQAFQYMKENLKKLYQDLIKEKD
QLNKLLDNIPIGVAYVDKDYNVIRVNKAFLDMFGNTDIKNLDFKDKNIRQDIIELSENEKIFIFEDVSPMVNAQRLSVWK
ETAQRVAHELKNPLTPIKLNIERLLRISKNHPEKLQDTINAVGDIVLKEIDKILKLLQDFKDFSNIEILDKSTQSIKDAI
LEAIELYKPYSVDFEIIGDNILEFDKEKIKIVFMNLIQNSIESKSTKIKIEIKPKEIIYQDNGEGIKEISKIFLPYYSSK
PTGTGLGLSIVKAIIQKHGWDIKALPSSAGALFVITIP

Sequences:

>Translated_598_residues
MRWLNINTFKKKVNLVLGLLALSIVLTSNIGFVLNLKHNPSINIYAFLAIININLFALLLASVIIFRKFIKLYYETKKKT
LRTKITTIILLYMFLPISLMMFASSFVIVESVKTFISDKTKLVLRTSIKLSKEIEQSQYEKAILYRNFLSRLVFYEDPYS
LVNHFDIRAVHEVSDCDNPIVENQKSYSICIMKGDKAYVFVVGKDAKLEKSSKALNRFAKEFIVLVKTRDILNGNYVAFI
VILALMVVLFTVWFGIFLARHISEPIEELSEAAKTLAKGDLDTKLPTPRTNDELSELIQAFQYMKENLKKLYQDLIKEKD
QLNKLLDNIPIGVAYVDKDYNVIRVNKAFLDMFGNTDIKNLDFKDKNIRQDIIELSENEKIFIFEDVSPMVNAQRLSVWK
ETAQRVAHELKNPLTPIKLNIERLLRISKNHPEKLQDTINAVGDIVLKEIDKILKLLQDFKDFSNIEILDKSTQSIKDAI
LEAIELYKPYSVDFEIIGDNILEFDKEKIKIVFMNLIQNSIESKSTKIKIEIKPKEIIYQDNGEGIKEISKIFLPYYSSK
PTGTGLGLSIVKAIIQKHGWDIKALPSSAGALFVITIP
>Mature_598_residues
MRWLNINTFKKKVNLVLGLLALSIVLTSNIGFVLNLKHNPSINIYAFLAIININLFALLLASVIIFRKFIKLYYETKKKT
LRTKITTIILLYMFLPISLMMFASSFVIVESVKTFISDKTKLVLRTSIKLSKEIEQSQYEKAILYRNFLSRLVFYEDPYS
LVNHFDIRAVHEVSDCDNPIVENQKSYSICIMKGDKAYVFVVGKDAKLEKSSKALNRFAKEFIVLVKTRDILNGNYVAFI
VILALMVVLFTVWFGIFLARHISEPIEELSEAAKTLAKGDLDTKLPTPRTNDELSELIQAFQYMKENLKKLYQDLIKEKD
QLNKLLDNIPIGVAYVDKDYNVIRVNKAFLDMFGNTDIKNLDFKDKNIRQDIIELSENEKIFIFEDVSPMVNAQRLSVWK
ETAQRVAHELKNPLTPIKLNIERLLRISKNHPEKLQDTINAVGDIVLKEIDKILKLLQDFKDFSNIEILDKSTQSIKDAI
LEAIELYKPYSVDFEIIGDNILEFDKEKIKIVFMNLIQNSIESKSTKIKIEIKPKEIIYQDNGEGIKEISKIFLPYYSSK
PTGTGLGLSIVKAIIQKHGWDIKALPSSAGALFVITIP

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=410, Percent_Identity=27.8048780487805, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=25.3333333333333, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68645; Mature: 68645

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLNINTFKKKVNLVLGLLALSIVLTSNIGFVLNLKHNPSINIYAFLAIININLFALLL
CCEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
ASVIIFRKFIKLYYETKKKTLRTKITTIILLYMFLPISLMMFASSFVIVESVKTFISDKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLVLRTSIKLSKEIEQSQYEKAILYRNFLSRLVFYEDPYSLVNHFDIRAVHEVSDCDNPI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCH
VENQKSYSICIMKGDKAYVFVVGKDAKLEKSSKALNRFAKEFIVLVKTRDILNGNYVAFI
HCCCCCEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHEEHEEEHHHCCCCHHHHH
VILALMVVLFTVWFGIFLARHISEPIEELSEAAKTLAKGDLDTKLPTPRTNDELSELIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
FQYMKENLKKLYQDLIKEKDQLNKLLDNIPIGVAYVDKDYNVIRVNKAFLDMFGNTDIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHCCCCCCC
LDFKDKNIRQDIIELSENEKIFIFEDVSPMVNAQRLSVWKETAQRVAHELKNPLTPIKLN
CCCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
IERLLRISKNHPEKLQDTINAVGDIVLKEIDKILKLLQDFKDFSNIEILDKSTQSIKDAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHH
LEAIELYKPYSVDFEIIGDNILEFDKEKIKIVFMNLIQNSIESKSTKIKIEIKPKEIIYQ
HHHHHHCCCCCCCEEEECCHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHEEEE
DNGEGIKEISKIFLPYYSSKPTGTGLGLSIVKAIIQKHGWDIKALPSSAGALFVITIP
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCEEEEEECC
>Mature Secondary Structure
MRWLNINTFKKKVNLVLGLLALSIVLTSNIGFVLNLKHNPSINIYAFLAIININLFALLL
CCEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
ASVIIFRKFIKLYYETKKKTLRTKITTIILLYMFLPISLMMFASSFVIVESVKTFISDKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLVLRTSIKLSKEIEQSQYEKAILYRNFLSRLVFYEDPYSLVNHFDIRAVHEVSDCDNPI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCH
VENQKSYSICIMKGDKAYVFVVGKDAKLEKSSKALNRFAKEFIVLVKTRDILNGNYVAFI
HCCCCCEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHEEHEEEHHHCCCCHHHHH
VILALMVVLFTVWFGIFLARHISEPIEELSEAAKTLAKGDLDTKLPTPRTNDELSELIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
FQYMKENLKKLYQDLIKEKDQLNKLLDNIPIGVAYVDKDYNVIRVNKAFLDMFGNTDIKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHCCCCCCC
LDFKDKNIRQDIIELSENEKIFIFEDVSPMVNAQRLSVWKETAQRVAHELKNPLTPIKLN
CCCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
IERLLRISKNHPEKLQDTINAVGDIVLKEIDKILKLLQDFKDFSNIEILDKSTQSIKDAI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHH
LEAIELYKPYSVDFEIIGDNILEFDKEKIKIVFMNLIQNSIESKSTKIKIEIKPKEIIYQ
HHHHHHCCCCCCCEEEECCHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHEEEE
DNGEGIKEISKIFLPYYSSKPTGTGLGLSIVKAIIQKHGWDIKALPSSAGALFVITIP
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]