Click here to switch to the map view.

The map label for this gene is dcuB [H]

Identifier: 194738234

GI number: 194738234

Start: 4437686

End: 4439026

Strand: Reverse

Name: dcuB [H]

Synonym: SeSA_A4556

Alternate gene names: 194738234

Gene position: 4439026-4437686 (Counterclockwise)

Preceding gene: 194737422

Following gene: 194734207

Centisome position: 94.27

GC content: 53.99

Gene sequence:

>1341_bases
ATGTTATTTAGTATACAGCTTCTCATAATATTAATATGTCTGTTTTATGGTGCCCGAAAGGGCGGGATCGCGCTCGGGTT
GTTGGGCGGTATTGGTCTGGTCATTCTGGTGTTTGTTTTCCATCTCCAGCCAGGTAAACCGCCCGTTGACGTAATGCTGG
TCATTATCGCGGTAGTCGCCGCGTCGGCAACGTTGCAGGCGTCAGGCGGGCTGGATGTGATGCTGCAGATTGCCGAAAAG
CTGCTGCGTCGCAACCCCAAATACGTCTCTATTGTGGCGCCGTTCGTCACCTGTACCCTGACGATTCTGTGTGGGACAGG
CCACGTGGTCTACACCATTTTGCCGATTATCTATGACGTGGCGATCAAGAATAATATCCGTCCGGAACGTCCAATGGCGG
CCAGTTCTATCGGCGCGCAAATGGGCATCATCGCCAGTCCGGTTTCCGTCGCCGTGGTTTCTCTGGTAGCGATGCTGGGC
AACGTGACATTTGACGGAAAACATCTGGAGTTCCTCGATCTGCTGTCGATCACCATCCCGTCTACCCTGCTCGGTATCCT
GGCAATCGGTATTTTTAGTTGGTTCCGCGGTAAAGATCTGGATAAAGACGAAGCGTTTCAGAAATTTATCTCCGTACCGG
AAAACCGTCAGTACGTGTACGGCGATACCGCGACGCTGCTGGATAAAAAACTGCCGAAAAGCAACTGGCTGGCGATGTGG
ATCTTCCTGGCGGCGATTGCCGTGGTCGCTCTCCTGGGCGCGGACTCCGACTTACGCCCAACCTTCGGCGGCAAACCGTT
GTCGATGGTGCTGGTCATTCAGATGTTCATGCTGCTGACCGGGGCGCTCATTATCATCCTGACCAAAACCAATCCTGCGT
CTATCTCAAAAAACGAAGTTTTTCGTTCCGGTATGATTGCGATTGTCGCGGTATACGGGATCGCCTGGATGGCGGAAACC
ATGTTCGGCGCGCATATGTCGGAAATTCAGGGCGTGCTGGGCGAAATGGTCAAAGAGTATCCGTGGGCCTACGCCATCGT
TCTGCTGCTGGTCTCCAAGTTTGTTAACTCCCAGGCAGCGGCGCTTGCGGCGATTGTTCCCGTCGCGCTGGCTATCGGTG
TCGATCCGGCGTATATCGTGGCCTCTGCGCCGGCATGTTATGGCTACTATATTCTGCCGACCTACCCAAGCGATCTGGCG
GCGATTCAGTTTGACCGTTCCGGCACAACACGTATTGGCCGCTTCGTCATTAACCACAGCTTCATTCTGCCGGGTTTGAT
TGGCGTGAGCGTCTCCTGCGTCTTTGGCTGGATCTTTGCCGCAATGTACGGATTCCTGTAA

Upstream 100 bases:

>100_bases
TTGAATATTCGCCATTTCCTGATGCTCATTCACACAAATCAGAAGATGGCTGTGATCCATTTATCAAAATTGACTGGGTT
TATCGCGAGGATAAATAAAA

Downstream 100 bases:

>100_bases
TGGCCGCGCGCGCCGCCCGGCTATGCGCGGCGCGCGACTTAGAGCCTGGCCCATGAGGCTCTTAATACATTTTCTTACTA
TTAGGCTGGAAGCACATGTC

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEK
LLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
NVTFDGKHLEFLDLLSITIPSTLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQYVYGDTATLLDKKLPKSNWLAMW
IFLAAIAVVALLGADSDLRPTFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAET
MFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLA
AIQFDRSGTTRIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL

Sequences:

>Translated_446_residues
MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEK
LLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
NVTFDGKHLEFLDLLSITIPSTLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQYVYGDTATLLDKKLPKSNWLAMW
IFLAAIAVVALLGADSDLRPTFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAET
MFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLA
AIQFDRSGTTRIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL
>Mature_446_residues
MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEK
LLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
NVTFDGKHLEFLDLLSITIPSTLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQYVYGDTATLLDKKLPKSNWLAMW
IFLAAIAVVALLGADSDLRPTFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAET
MFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLA
AIQFDRSGTTRIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=446, Percent_Identity=97.7578475336323, Blast_Score=793, Evalue=0.0,
Organism=Escherichia coli, GI1790580, Length=441, Percent_Identity=36.734693877551, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 47898; Mature: 47898

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVA
CEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDV
HHHHEECCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGNVTFDGKHLEFLDLLSITIP
HHHCCCCCCCCCHHHHHCCHHCHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
STLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQYVYGDTATLLDKKLPKSNWLAMW
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCCHHHHH
IFLAAIAVVALLGADSDLRPTFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHH
FRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHH
ALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTRIGRFVINHS
HHHHHHHHHHHHCCCCHHHEECCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHCC
FILPGLIGVSVSCVFGWIFAAMYGFL
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVA
CEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDV
HHHHEECCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGNVTFDGKHLEFLDLLSITIP
HHHCCCCCCCCCHHHHHCCHHCHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
STLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQYVYGDTATLLDKKLPKSNWLAMW
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCCHHHHH
IFLAAIAVVALLGADSDLRPTFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHH
FRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHH
ALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTRIGRFVINHS
HHHHHHHHHHHHCCCCHHHEECCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHCC
FILPGLIGVSVSCVFGWIFAAMYGFL
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]