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The map label for this gene is fimH [H]

Identifier: 194738098

GI number: 194738098

Start: 595727

End: 596734

Strand: Direct

Name: fimH [H]

Synonym: SeSA_A0592

Alternate gene names: 194738098

Gene position: 595727-596734 (Clockwise)

Preceding gene: 194735116

Following gene: 194736416

Centisome position: 12.65

GC content: 51.59

Gene sequence:

>1008_bases
ATGAAAATATACTCAGCGCTATTGCTGGCGGGGACCGCGCTCTTTTTCACCCATCCCGCGCTGGCGACGGTTTGCCGCAA
TTCAAACGGGACGGCGACCGATATCTTTTACGACCTGTCAGATGTTTTCACCAGCGGCAATAATCAGCCGGGACAGGTGG
TTACGCTACCGGAAAAATCAGGTTGGGTCGGCGTAAACGCGACGTGCCCGGCGGGGACAACGGTGAATTATACCTACCGA
AGCTATGTATCAGAATTACCGGTACAAAGCACCGAAGGAAATTTTAAATACCTCAAACTGAATGACTACCTTCTGGGCGC
GATGAGCATAACCGATAGTGTCACTGGCGTATTTTATCCGCCCCGTAACTATATTCGCATGGGCGTCGACTATAACGTGT
CGCAGCAAAAGCCGTTTGGCGTGCAGGACTCAAAGCTGGTTTTTAAATTAAAAGTGATACGGCCTTTTATTAATATGGTG
ACGATCCCTCGCCAGACAATGTTTACCGTCTATGTGACGACCTCTACCAGCGACGCGTTGAGCACGCCGGTATATACCAT
TAGCTACAGCGGCAAAGTGGAAGTGCCGCAAAACTGCGAAGTGAATGCCGGACAGGTCGTGGAGTTTGATTTCGGCGATA
TCGGCGCGTCGTTATTTAGTCAGGCGGGGGCGGGTAATCGTCCGCAAGGCGTCACGCCGCAAACGAAAACTATCGCTATC
AAATGTACCAACGTCGCGGCGCAGGCCTATTTATCGATGCGGCTTGAAGCCGAAAAGGCCTCAGGGCAGGCGATGGTGTC
CGATAATCCGGATTTAGGTTTTGTAGTTGCTAATAGCAACGGTACGCCGCTCACACCCAATAATTTGTCGAGTAAAATTC
CGTTTCATCTTGATGATAACGCCGCCGCTCGCGTAGGTATTCGCGCCTGGCCGATCAGCGTGACGGGGAATAAACCGGCG
GAAGGGCCGTTTACTGCGCGCGGCTATCTACGAGTCGATTATGATTAA

Upstream 100 bases:

>100_bases
GTATCGCCCCTTACGCCCTGGCGGAGGATAGTCTGAAGCAGGCGATTACGATAGCCAGCGCGACCTGTATCCGTCCGGCG
TCATAAAAGGAAAAATAGAG

Downstream 100 bases:

>100_bases
GGAGGCATAATGATCCTTCGGCGCGTTTTCATCGCTATCGGTTGTGTTTTGTTCAGCCCGCTGAGTCAGGCCAACTCATC
TCTGGGCGAAGTGAATATTG

Product: mannose binding protein FimH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVTGVFYPPRNYIRMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMV
TIPRQTMFTVYVTTSTSDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPA
EGPFTARGYLRVDYD

Sequences:

>Translated_335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVTGVFYPPRNYIRMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMV
TIPRQTMFTVYVTTSTSDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPA
EGPFTARGYLRVDYD
>Mature_335_residues
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKSGWVGVNATCPAGTTVNYTYR
SYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVTGVFYPPRNYIRMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMV
TIPRQTMFTVYVTTSTSDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPA
EGPFTARGYLRVDYD

Specific function: Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Seems to be a mannose-binding adhesin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI145693100, Length=326, Percent_Identity=70.2453987730061, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1787173, Length=196, Percent_Identity=27.5510204081633, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789534, Length=307, Percent_Identity=27.0358306188925, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36206; Mature: 36206

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKS
CCHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEEEEHHHHHHCCCCCCCEEEECCCCC
GWVGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVTGVFYP
CEEEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCEEEEEECCEEEEEEEECCCCCEEEEC
PRNYIRMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMVTIPRQTMFTVYVTTSTSDAL
CHHHEEECCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHEECCCCEEEEEEEEECCCCHH
STPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
CCCEEEEEECCEEECCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDN
EEECHHHEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAARVGIRAWPISVTGNKPAEGPFTARGYLRVDYD
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFTSGNNQPGQVVTLPEKS
CCHHHHHHHHHHHHHHCCHHHHHHEECCCCCEEEEEEEHHHHHHCCCCCCCEEEECCCCC
GWVGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLNDYLLGAMSITDSVTGVFYP
CEEEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCEEEEEECCEEEEEEEECCCCCEEEEC
PRNYIRMGVDYNVSQQKPFGVQDSKLVFKLKVIRPFINMVTIPRQTMFTVYVTTSTSDAL
CHHHEEECCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHEECCCCEEEEEEEEECCCCHH
STPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGASLFSQAGAGNRPQGVTPQTKTIAI
CCCEEEEEECCEEECCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
KCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVVANSNGTPLTPNNLSSKIPFHLDDN
EEECHHHEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAARVGIRAWPISVTGNKPAEGPFTARGYLRVDYD
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]