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The map label for this gene is qseC [H]

Identifier: 194737888

GI number: 194737888

Start: 2839486

End: 2840901

Strand: Reverse

Name: qseC [H]

Synonym: SeSA_A2927

Alternate gene names: 194737888

Gene position: 2840901-2839486 (Counterclockwise)

Preceding gene: 194737394

Following gene: 194734446

Centisome position: 60.33

GC content: 56.07

Gene sequence:

>1416_bases
ATGAAGTGGGTTAAGCCGCAATCGTTGTACCTGCAACTCTTGCTGTTCCTGGGGTTGCCGCTGATTCTGCTATGGGGGCT
GTCGGCGTTTAACAGTTATGTCAATGCGCTACAGGCCGCCACTCAGGCTTATGACCGTACGTTGCTCTCCTCGGCGCGAA
CGGTATCGGAACGGCTGGTGGTGCGCAATAACCATCTGGAAGTTAACGTGCCTTGGGTGGTGCTGGATAGCTTCGAGCTT
AATATGAATGATCGACTCTATTACAAAGTCGTCGACCCTTCCGGAAAGGTCATTTCCGGTTATGACGATCTGCCCGCCAT
GCCGCCTGCTACGCCTCGTACCCGGCTTTATCCGGCGCTGGCGTGGTTCTATCATACCGAGTATCGCGGCGAGGCGATCC
GCGTGGCGCGTTTGCTACAGCCGGTCAACGAAGGCGGCATTATCGGCATGGCGGAGATTTATGTCGCAGAGACGCTGCAG
TCCCGTCGTTATCTGGCGGGCCAACTGCTGTTCTCTTCCTGGATCTCACAGGGGCTGCTGGTGTTGCTGACCCTGGTGCT
GGTTGGCTGGTTATTACGCCGGATCCTGCGCCCTATGCGTCAACTTTCGTCATTAATGGTACGCCGCGAACCGGGTCTGT
TAACGCCGCTGCCGGAACTGCTGCCGTGGTCGGAAACACGCTTGTTAATCGTGGCGTTTAATCGCTACATTGACAGGCTC
CGCGGCATCCTCTCCCGGCAGGAACGCTTTAGCGCCGATGCTTCTCACCAGTTAAAAACGCCGCTGGCGGTGTTAAAAAC
GCAGGCGGCGGTGGCGTTAGCCAGCCAGCACCCTCATCACTGGTACGAAAGTCTGCAGGCGATGAGCGTAACGCTGGATA
GCACCATTCAGCTCACGGAAAGATTGTTGCAACTTTCTGCGGTAAAGCATAAAGAGCAGGGCGAGCGGCGTTTTTCCCCG
GTGAATCTGTACGATATCGTACAGAGCGGCTGTTTTACCCGCCTGGCGCAGGCGCGGAGTAAACATATCGACCTGGGCTA
CGAAGGCGAACAGGAAGCGATGTGGATCGAGGGGGATGAGGTACTGCTTAGCGAGCTGTGCGGAAACTTGCTGGATAATG
CGCTGAAATACACGCCTGAGCAAGGCATCGTCACCGCGCGGCTTGAACGGGATAGTGATGCCGTGACGCTGGTTGTCGAA
GATAGCGGCCCCGGTATTGATGATGAACACATCCATCTGGCGCTACAGCCGTTCCACCGGCTCGATAATGTAGGAAATGT
GGCCGGGGCGGGCATTGGTCTGGCTTTGGTCAATGATATCGCACGCCTGCACCGTACTCATCCCCATTTTTCCCGTAGCG
AAGCGTTGGGAGGGTTATACGTTCGGATACGCTTTTTAAGCCTTGTTCCGCAGTAA

Upstream 100 bases:

>100_bases
AGCATCGAACTTTATATTCATCGACTGCGTAAAAAACTCCAGGGAAGCGATGTACGAATTACGACGCTGCGCGGCCTGGG
TTATGTGCTGGAGCGCGGCG

Downstream 100 bases:

>100_bases
TGCGCACAAATGTGTCAGCGGTAAAGCACGTTTACAAAAAGTCGCATCTTGAGGTGTGACGTTTTAATCAAATGATCATA
CATTTCCCCTACAAACCGTA

Product: tricarboxylic transport: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFEL
NMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEIYVAETLQ
SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSP
VNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDSDAVTLVVE
DSGPGIDDEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ

Sequences:

>Translated_471_residues
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFEL
NMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEIYVAETLQ
SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSP
VNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDSDAVTLVVE
DSGPGIDDEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ
>Mature_471_residues
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFEL
NMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEIYVAETLQ
SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSP
VNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDSDAVTLVVE
DSGPGIDDEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=301, Percent_Identity=30.8970099667774, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=28.9752650176678, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786783, Length=292, Percent_Identity=27.7397260273973, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=282, Percent_Identity=29.0780141843972, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=261, Percent_Identity=27.2030651340996, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=27.1317829457364, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=27.8145695364238, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=26.3736263736264, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=299, Percent_Identity=25.752508361204, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=27.1889400921659, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53159; Mature: 53159

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRNNHLEVNVPWVVLDSFELNMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPAL
EECCEEEEEECEEEEECEEECCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHH
AWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEIYVAETLQSRRYLAGQLLFSSWISQGLL
HHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHH
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTE
HHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLLQLSAVKHKEQGERRFSPVNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHH
VLLSELCGNLLDNALKYTPEQGIVTARLERDSDAVTLVVEDSGPGIDDEHIHLALQPFHR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEHHHHH
LDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ
HCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAYDRTLLSSARTVSERLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRNNHLEVNVPWVVLDSFELNMNDRLYYKVVDPSGKVISGYDDLPAMPPATPRTRLYPAL
EECCEEEEEECEEEEECEEECCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHH
AWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEIYVAETLQSRRYLAGQLLFSSWISQGLL
HHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLPELLPWSETRLLIVAFNRYIDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHH
RGILSRQERFSADASHQLKTPLAVLKTQAAVALASQHPHHWYESLQAMSVTLDSTIQLTE
HHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLLQLSAVKHKEQGERRFSPVNLYDIVQSGCFTRLAQARSKHIDLGYEGEQEAMWIEGDE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHH
VLLSELCGNLLDNALKYTPEQGIVTARLERDSDAVTLVVEDSGPGIDDEHIHLALQPFHR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEHHHHH
LDNVGNVAGAGIGLALVNDIARLHRTHPHFSRSEALGGLYVRIRFLSLVPQ
HCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]