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The map label for this gene is hoxN [H]

Identifier: 194734446

GI number: 194734446

Start: 2838340

End: 2839353

Strand: Reverse

Name: hoxN [H]

Synonym: SeSA_A2926

Alternate gene names: 194734446

Gene position: 2839353-2838340 (Counterclockwise)

Preceding gene: 194737888

Following gene: 194734353

Centisome position: 60.3

GC content: 50.0

Gene sequence:

>1014_bases
ATGAATAATCATACTAAACGACGGGGAATAGCATTAACCGTCTTTCTTGTTGGGGTTAACATCCTGGCCTGGATTTGGGC
GTTCTGTGTTTTTCATCACCATGCAGTCATGCTAAGCGCAGCCATACTGGCGTATAGCTTTGGGCTGCGTCATGCGGTTG
ATGCCGATCATATCGCAGCCATCGATACCGTCACCCGTAAACTGATGCAGCAGGGTAAAACGCCTTTAGGCGTGGGGGCG
TTTTTTTCATTGGGTCATTCGACCATTGTCGTTCTGGCATGTCTGGCGATTGTTGTGACGTCGATGGCATTTCGCGATCG
TATTGATGTTTTGCATCAATATGGTTCGTTGATTGGTACGGCTGTTTCCGCTTTTTTTCTGCTGGCGATGGCCCTGCTTA
ACCTGTTTATTTTGTTCAACGTCTGGCGGCAATTTCGCTCGGTTACCCGCGGCGAGTCAGTGAGGGCGCATGACGAGGCG
ATACCTGGCGGGCTGATGACGCGTATATTTCAGCGTACGTTTCGTTTGGTCACTTCCAGTTGGCATATGTATTTTGTCGG
TTTTCTGTTTGGTCTGGGATTTGATACCGCAACCGAGGTTGGGTTGCTGGGCATTTCCGCTTCAGCAGCTAACCAGGGGC
TATCTCTCTGGTCGATGATGATTTTTCCTGTGCTGTTTACCGCCGGGATGGCGCTGGTGGATTCCCTGGATAACTTTGTC
ATGGTCGGCGCTTACGGTTGGGCTTTCTCGCATCCATTACGTAAGCTTTATTATAATATGACCATTACCGCCGCATCTGT
CATTGTCGCGCTGGCGATTGGCGGGCTTGAGGCGCTGGGGTTGATTGATGATGCGTTACAGTTAAGCGGAACATTTTGGC
AGACCGTAAGCACGCTTAACGATCATATGGGGAATGTGGGCTTCTGGGTAGTGGGCGCTTTTGTGCTATTCTGGCTGCTC
TCGTTGTTGAATTATCGCTGGCGCGGCTATGATAAAATCACCCTCAATATCTGA

Upstream 100 bases:

>100_bases
TACAAAAAGTCGCATCTTGAGGTGTGACGTTTTAATCAAATGATCATACATTTCCCCTACAAACCGTAGCGTTAATTAAA
AATATAGTGGGTGCAGGGGC

Downstream 100 bases:

>100_bases
TTGATTTCTGTAAAAATAACATTTCGGCAGTGGTGTCATATCATTGCCGAAGCATTTTATCTCCTGAGAGTATATTCTTC
CCGGTAAGTGCGTTATTTTT

Product: high-affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNNHTKRRGIALTVFLVGVNILAWIWAFCVFHHHAVMLSAAILAYSFGLRHAVDADHIAAIDTVTRKLMQQGKTPLGVGA
FFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGTAVSAFFLLAMALLNLFILFNVWRQFRSVTRGESVRAHDEA
IPGGLMTRIFQRTFRLVTSSWHMYFVGFLFGLGFDTATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFV
MVGAYGWAFSHPLRKLYYNMTITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLNDHMGNVGFWVVGAFVLFWLL
SLLNYRWRGYDKITLNI

Sequences:

>Translated_337_residues
MNNHTKRRGIALTVFLVGVNILAWIWAFCVFHHHAVMLSAAILAYSFGLRHAVDADHIAAIDTVTRKLMQQGKTPLGVGA
FFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGTAVSAFFLLAMALLNLFILFNVWRQFRSVTRGESVRAHDEA
IPGGLMTRIFQRTFRLVTSSWHMYFVGFLFGLGFDTATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFV
MVGAYGWAFSHPLRKLYYNMTITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLNDHMGNVGFWVVGAFVLFWLL
SLLNYRWRGYDKITLNI
>Mature_337_residues
MNNHTKRRGIALTVFLVGVNILAWIWAFCVFHHHAVMLSAAILAYSFGLRHAVDADHIAAIDTVTRKLMQQGKTPLGVGA
FFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGTAVSAFFLLAMALLNLFILFNVWRQFRSVTRGESVRAHDEA
IPGGLMTRIFQRTFRLVTSSWHMYFVGFLFGLGFDTATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFV
MVGAYGWAFSHPLRKLYYNMTITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLNDHMGNVGFWVVGAFVLFWLL
SLLNYRWRGYDKITLNI

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37212; Mature: 37212

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNHTKRRGIALTVFLVGVNILAWIWAFCVFHHHAVMLSAAILAYSFGLRHAVDADHIAA
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IDTVTRKLMQQGKTPLGVGAFFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGT
HHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSAFFLLAMALLNLFILFNVWRQFRSVTRGESVRAHDEAIPGGLMTRIFQRTFRLVTSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
WHMYFVGFLFGLGFDTATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFV
HHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEE
MVGAYGWAFSHPLRKLYYNMTITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLN
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DHMGNVGFWVVGAFVLFWLLSLLNYRWRGYDKITLNI
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MNNHTKRRGIALTVFLVGVNILAWIWAFCVFHHHAVMLSAAILAYSFGLRHAVDADHIAA
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IDTVTRKLMQQGKTPLGVGAFFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGT
HHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSAFFLLAMALLNLFILFNVWRQFRSVTRGESVRAHDEAIPGGLMTRIFQRTFRLVTSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
WHMYFVGFLFGLGFDTATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFV
HHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEE
MVGAYGWAFSHPLRKLYYNMTITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLN
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DHMGNVGFWVVGAFVLFWLLSLLNYRWRGYDKITLNI
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]