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The map label for this gene is metA [H]

Identifier: 194737138

GI number: 194737138

Start: 4266813

End: 4267742

Strand: Direct

Name: metA [H]

Synonym: SeSA_A4393

Alternate gene names: 194737138

Gene position: 4266813-4267742 (Clockwise)

Preceding gene: 194737721

Following gene: 194736609

Centisome position: 90.61

GC content: 49.14

Gene sequence:

>930_bases
ATGCCGATTCGCGTGCTGGACGAGCTACCCGCCGTCAATTTTTTACGTGAGGAGAATGTCTTCGTCATGACGACTTCTCG
CGCATCAGGTCAGGAAATTCGCCCGCTAAAGGTACTTATCCTTAACCTGATGCCGAAGAAGATTGAAACGGAAAATCAGT
TTCTGCGCTTGCTATCGAACTCGCCATTACAGGTCGATATTCAACTACTGCGGATAGATGCCCGCGAGTCGAGGAACACG
CCAGCCGAGCATCTGAACAACTTTTACTGTAACTTCGACGATATCTGCGATCAGAACTTTGATGGGCTTATCGTGACCGG
AGCGCCGCTGGGTCTGGTGGAGTTTAATGACGTGGCTTACTGGCCGCAGATTAGGCAGGTGCTGGAATGGGCGAAAGATC
ACGTTACTTCGACGCTATTTGTCTGTTGGGCCGTTCAGGCCGCACTCAATATTCTTTATGGTATCCCTAAGCAGACCCGT
ACAGATAAACTTTCCGGCGTCTATGAACATCACATCCTTCATCCTCATGCTCTGTTGACGCGTGGTTTTGATGATTCGTT
TCTTGCGCCACACTCACGCTATGCCGATTTCCCGGCGGCGCTAATACGGGATTATACGGATCTTGAAATTCTGGCCGAAA
CAGAAGAGGGGGATGCGTACCTGTTTGCCAGCAAAGATAAACGTATTGCGTTTGTCACCGGTCATCCTGAATATGACGCC
CATACGTTAGCGGGTGAATATTTTCGTGACGTTGAGGCCGGGTTAAATCCGGAGGTTCCGTACAACTATTTCCCAAAAAA
CGATCCGCAAAACATACCGCGCGCAACCTGGCGCAGCCACGGTAATTTACTGTTTACTAACTGGCTCAACTATTATGTCT
ACCAGATTACGCCATATGATCTGCGTCACATGAATCCAACCCTGGATTAA

Upstream 100 bases:

>100_bases
TCACCTTGAACTTGCAGACTCGACATTCGCCTGATTTCTGAGTATCTTCAGCTATCTGGATGTCTAAACGTTTAAACGTA
TGTCGTGAGGTTATCAGGTT

Downstream 100 bases:

>100_bases
TCTTCTGCTCCTGACGATCCTAAAGCGTTTCAGCATGTTGAATCAGGCACCTTCGGGTGCCTTTTTTATTTCCGAAACGC
ACCTCATCATGTAATTAAAT

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNT
PAEHLNNFYCNFDDICDQNFDGLIVTGAPLGLVEFNDVAYWPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTR
TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDA
HTLAGEYFRDVEAGLNPEVPYNYFPKNDPQNIPRATWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD

Sequences:

>Translated_309_residues
MPIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNT
PAEHLNNFYCNFDDICDQNFDGLIVTGAPLGLVEFNDVAYWPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTR
TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDA
HTLAGEYFRDVEAGLNPEVPYNYFPKNDPQNIPRATWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
>Mature_308_residues
PIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNTP
AEHLNNFYCNFDDICDQNFDGLIVTGAPLGLVEFNDVAYWPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTRT
DKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAH
TLAGEYFRDVEAGLNPEVPYNYFPKNDPQNIPRATWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=309, Percent_Identity=95.1456310679612, Blast_Score=613, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35671; Mature: 35540

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSN
CCCCHHHHCCCHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCC
SPLQVDIQLLRIDARESRNTPAEHLNNFYCNFDDICDQNFDGLIVTGAPLGLVEFNDVAY
CCCEEEEEEEEEECHHCCCCCHHHHCCCCCCHHHHCCCCCCEEEEECCCCCEEEECCCCC
WPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
RGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDA
CCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCEEEEECCCCEEEEEECCCCCCC
HTLAGEYFRDVEAGLNPEVPYNYFPKNDPQNIPRATWRSHGNLLFTNWLNYYVYQITPYD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECEEEEEEECCHH
LRHMNPTLD
HHCCCCCCC
>Mature Secondary Structure 
PIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSN
CCCHHHHCCCHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCC
SPLQVDIQLLRIDARESRNTPAEHLNNFYCNFDDICDQNFDGLIVTGAPLGLVEFNDVAY
CCCEEEEEEEEEECHHCCCCCHHHHCCCCCCHHHHCCCCCCEEEEECCCCCEEEECCCCC
WPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
RGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDA
CCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCEEEEECCCCEEEEEECCCCCCC
HTLAGEYFRDVEAGLNPEVPYNYFPKNDPQNIPRATWRSHGNLLFTNWLNYYVYQITPYD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECEEEEEEECCHH
LRHMNPTLD
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA