Click here to switch to the map view.

The map label for this gene is cpsB [H]

Identifier: 194736911

GI number: 194736911

Start: 2210044

End: 2211480

Strand: Reverse

Name: cpsB [H]

Synonym: SeSA_A2338

Alternate gene names: 194736911

Gene position: 2211480-2210044 (Counterclockwise)

Preceding gene: 194736458

Following gene: 194737286

Centisome position: 46.96

GC content: 60.13

Gene sequence:

>1437_bases
ATGCGTCAGACAAAACTTTACCCGGTTGTGATGGCCGGTGGCTCCGGTAGCCGATTGTGGCCGCTTTCTCGCGTGCTTTA
TCCAAAACAGTTTTTGTGCCTGAAAGGCGATCTCACCATGCTGCAAACCACCATTTGCCGTCTGAACGGCGTGGAGTGCG
AAAGCCCGGTGGTTATCTGCAACGAACAGCACCGTTTTATCGTTGCCGAACAGCTCCGCCAGCTCAATAAGCTGACGGAG
AACATTATTCTTGAGCCCGCCGGGCGCAATACCGCGCCGGCGATTGCGCTGGCGGCGCTGGCAGCGACGCGCCAGCATAC
GGACTGCGATCCGCTGATGCTGGTACTGGCGGCGGATCATGCGATCGCCAATGAAGAGGCCTTCCGCGACGCGGTGCGCG
GCGCCATGCCCTATGCTTACGCGGGCAAACTGGTGACCTTCGGTATTGTGCCGGATCTGCCGGAAACCGGCTATGGCTAT
ATCCGGCGCGGTGATGTCGTGCCGGGCGCGACGGATGCGGTGGCTTTTGAGGTGGCGCAGTTCGTTGAGAAGCCGGGGCT
GGAAACCGCCCAGGCCTACGTCGCCAGCGGCGATTACTACTGGAACAGCGGCATGTTTCTGTTCCGCGCCGGACGCTATC
TGGAAGAGCTGAAAAAGTTCCGCCCCGATATTCTGGCCGCTTGTGAACAGGCGATGCGCGGCGTCGATCCGGATCTTGAC
TTCATTCGTGTGGATGAAGAGGCCTTCCTCGCCTGTCCGGAAGAGTCCATTGACTACGCGGTGATGGAGCGGACGGCGGA
CGCGGTGGTGATGCCAATGGACGCGGGCTGGAGCGATGTCGGCTCGTGGTCCTCGCTGTGGGAAATCAGCGCCCACACCC
CGGAGGGAAATGTCCACCACGGCGACGTCATCAGCCATAAAACGGAAAACAGCTACGTTTACGCCGAATCCGGCCTGGTG
ACCACCGTCGGTGTGAAGGATCTGGTGGTGGTGCAGACCAAAGACGCCGTGCTGATTGCCGATCGCCACGCGGTGCAGGA
CGTGAAAAAGGTGGTGGAGAAGATCAAGGCCGACGGACGCCATGAGCACCACATGCATCGCGAGGTTTACCGTCCGTGGG
GCAAATACGACTCCATCGACGCGGGCGAGCGCTATCAGGTGAAGCGCATTACCGTCAAGCCGGGGGAAGGACTGTCGGTA
CAGATGCACCATCACCGCGCCGAGCACTGGGTGGTGGTGGCAGGGACCGCCAGAGTCACCATCAACGGCGAGGTTAAGCT
GCTCGGTGAAAACGAGTCCATCTATATTCCGCTGGGGGCGACCCACTGCCTGGAAAATCCGGGAAAAATACCGCTCGATT
TAATTGAAGTGCGTTCCGGCTCGTATCTCGAAGAGGACGACGTGGTGCGGTTCGAGGACCGTTACGGGCGGGTCTGA

Upstream 100 bases:

>100_bases
CCATGCCGAAAAACAACACGACGGCACGTGAATACGCCGAACGCACGCTCAATAAAGAGAACGTGCTACGCCAATTTATT
GCAGATATTCGGGGATGATA

Downstream 100 bases:

>100_bases
CGCCTGCAATGGTGCCCGGTAAGCGCAACGCGCCATCCGGCAATGAACAACAATAACGATGTTGGCCATTTACGGTCAGG
GCTAACTGTTGCCTGAAGAA

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTE
NIILEPAGRNTAPAIALAALAATRQHTDCDPLMLVLAADHAIANEEAFRDAVRGAMPYAYAGKLVTFGIVPDLPETGYGY
IRRGDVVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPDILAACEQAMRGVDPDLD
FIRVDEEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVGSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLV
TTVGVKDLVVVQTKDAVLIADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEGLSV
QMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFEDRYGRV

Sequences:

>Translated_478_residues
MRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTE
NIILEPAGRNTAPAIALAALAATRQHTDCDPLMLVLAADHAIANEEAFRDAVRGAMPYAYAGKLVTFGIVPDLPETGYGY
IRRGDVVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPDILAACEQAMRGVDPDLD
FIRVDEEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVGSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLV
TTVGVKDLVVVQTKDAVLIADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEGLSV
QMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFEDRYGRV
>Mature_478_residues
MRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTE
NIILEPAGRNTAPAIALAALAATRQHTDCDPLMLVLAADHAIANEEAFRDAVRGAMPYAYAGKLVTFGIVPDLPETGYGY
IRRGDVVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPDILAACEQAMRGVDPDLD
FIRVDEEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVGSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLV
TTVGVKDLVVVQTKDAVLIADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEGLSV
QMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFEDRYGRV

Specific function: Involved in the biosynthesis of the capsular polysaccharide colanic acid [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=478, Percent_Identity=91.0041841004184, Blast_Score=879, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 53160; Mature: 53160

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVIC
CCCCEEEEEEEECCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEE
NEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAATRQHTDCDPLMLVLAADH
CCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCC
AIANEEAFRDAVRGAMPYAYAGKLVTFGIVPDLPETGYGYIRRGDVVPGATDAVAFEVAQ
HHCCHHHHHHHHHHCCCHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHH
FVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPDILAACEQAMRGVDPDLD
HHHCCCCCHHHHEEECCCEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
FIRVDEEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVGSWSSLWEISAHTPEGNVHH
EEEECCHHEEECCCHHCCHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCC
GDVISHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRHAVQDVKKVVEKIKADGR
CCCCCCCCCCCEEEECCCEEEEECCCEEEEEEECCEEEEECHHHHHHHHHHHHHHHCCCC
HEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTARVT
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEEEE
INGEVKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFEDRYGRV
ECCEEEEEECCCEEEEECCHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEHHHCCCC
>Mature Secondary Structure
MRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVIC
CCCCEEEEEEEECCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEE
NEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAATRQHTDCDPLMLVLAADH
CCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCC
AIANEEAFRDAVRGAMPYAYAGKLVTFGIVPDLPETGYGYIRRGDVVPGATDAVAFEVAQ
HHCCHHHHHHHHHHCCCHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHH
FVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEELKKFRPDILAACEQAMRGVDPDLD
HHHCCCCCHHHHEEECCCEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
FIRVDEEAFLACPEESIDYAVMERTADAVVMPMDAGWSDVGSWSSLWEISAHTPEGNVHH
EEEECCHHEEECCCHHCCHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCC
GDVISHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRHAVQDVKKVVEKIKADGR
CCCCCCCCCCCEEEECCCEEEEECCCEEEEEEECCEEEEECHHHHHHHHHHHHHHHCCCC
HEHHMHREVYRPWGKYDSIDAGERYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTARVT
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEEEE
INGEVKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFEDRYGRV
ECCEEEEEECCCEEEEECCHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1712067; 11677609 [H]