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The map label for this gene is cpsG [H]

Identifier: 194737286

GI number: 194737286

Start: 2208563

End: 2209933

Strand: Reverse

Name: cpsG [H]

Synonym: SeSA_A2337

Alternate gene names: 194737286

Gene position: 2209933-2208563 (Counterclockwise)

Preceding gene: 194736911

Following gene: 194738330

Centisome position: 46.93

GC content: 62.07

Gene sequence:

>1371_bases
ATGACAAAATTAACCTGTTTCAAGGCCTACGACATTCGCGGCAGGCTGGGCGAAGAGCTCAATGAAGATATCGCGTGGCG
GATTGGCCGCGCTTACGGCGAATATTTAAAACCGAAAACCATCGTGCTGGGCGGCGACGTGCGCCTGACCAGCGAGGCGC
TGAAGCTGGCGCTGGCGAAAGGGTTACAGGACGCGGGCGTCGACGTGCTGGATATCGGTATGTCCGGCACCGAAGAGATT
TACTTCGCCACCTTCCACCTCGGCGTGGACGGCGGTATTGAAGTGACCGCCAGCCATAACCCGATGGACTACAACGGTAT
GAAGCTGGTGCGCGAGGGCGCCCGCCCGATAAGCGGCGACACCGGTCTGCGCGACGTTCAGCGTCTGGCGGAAGCGGGCG
ATTTCCCGCCGGTGAACGACGCCGCGCGCGGCAGCTACAGACAAATCAGCCTGCGCGACGCCTACATCGACCACCTGCTC
GCCTACATCAGTGTTAACAATCTCACCCCGCTGAAGCTGGTGGTGAATTCCGGCAACGGGGCGGCGGGGCCGGTCATTGA
CGCCATCGAAGCGCGTCTGAAGGCGCTGGGCGCGCCGGTGGAGTTCATCAAAATCCACAACACCCCGGACGGCACCTTCC
CGAACGGCATTCCCAACCCGTTGCTGCCGGAGTGTCGCGACGACACCCGCAAGGCCGTTATTGAACACGGGGCGGACATG
GGCATCGCCTTTGACGGCGACTTCGACCGCTGCTTCCTGTTCGATGAGAAAGGGCAGTTTATCGAGGGGTACTACATCGT
CGGGCTGCTGGCGGAAGCGTTTCTGGAAAAACACCCGGGGGCGAAGATTATCCACGACCCGCGCCTGACCTGGAACACGG
AGGCAGTGGTGACGGCGGCGGGCGGGACGCCGGTGATGTCAAAAACCGGGCACGCCTTTATCAAGGAGCGGATGCGTACG
GAGGATGCCATTTATGGCGGGGAAATGAGCGCGCATCACTATTTTCGTGATTTTGCCTACTGTGACAGCGGAATGATCCC
GTGGCTGCTGGTGGCGGAGCTGGTGTGCCTGAAGGGACAGTCGCTGGGTGAACTGGTCCGCGACCGGATGGCGGCGTTCC
CGGCGAGCGGGGAAATCAACAGCAGGCTGGCGGAGCCGGCAGCGGCCATCGCGCGGGTGGAAGCGCACTTCGCGGAAGAG
GCGCAGGCGGTGGACCGCACGGACGGACTCAGCATGTCGTTCGCCGACTGGCGTTTCAACCTGCGCTCGTCGAACACCGA
ACCGGTGGTGCGCCTGAATGTGGAATCACGCGGCGATATTCCGCTGATGGAAGCGCGAACACGCACTCTGCTGGCGCTGC
TGAATCAGTAA

Upstream 100 bases:

>100_bases
GGTGCCCGGTAAGCGCAACGCGCCATCCGGCAATGAACAACAATAACGATGTTGGCCATTTACGGTCAGGGCTAACTGTT
GCCTGAAGAAGGGTAAGAAC

Downstream 100 bases:

>100_bases
CGTCAGATCTCCCCTTACCGCCTGCGGGTAAGGGGCCAATCACAGGAACAACGATGACAAATCTAAAAAAGCGCGAACGA
GCCAAAACCAATGCATCGTT

Product: phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLGGDVRLTSEALKLALAKGLQDAGVDVLDIGMSGTEEI
YFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEAGDFPPVNDAARGSYRQISLRDAYIDHLL
AYISVNNLTPLKLVVNSGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIPNPLLPECRDDTRKAVIEHGADM
GIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRT
EDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGQSLGELVRDRMAAFPASGEINSRLAEPAAAIARVEAHFAEE
AQAVDRTDGLSMSFADWRFNLRSSNTEPVVRLNVESRGDIPLMEARTRTLLALLNQ

Sequences:

>Translated_456_residues
MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLGGDVRLTSEALKLALAKGLQDAGVDVLDIGMSGTEEI
YFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEAGDFPPVNDAARGSYRQISLRDAYIDHLL
AYISVNNLTPLKLVVNSGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIPNPLLPECRDDTRKAVIEHGADM
GIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRT
EDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGQSLGELVRDRMAAFPASGEINSRLAEPAAAIARVEAHFAEE
AQAVDRTDGLSMSFADWRFNLRSSNTEPVVRLNVESRGDIPLMEARTRTLLALLNQ
>Mature_455_residues
TKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLGGDVRLTSEALKLALAKGLQDAGVDVLDIGMSGTEEIY
FATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEAGDFPPVNDAARGSYRQISLRDAYIDHLLA
YISVNNLTPLKLVVNSGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIPNPLLPECRDDTRKAVIEHGADMG
IAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKHPGAKIIHDPRLTWNTEAVVTAAGGTPVMSKTGHAFIKERMRTE
DAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGQSLGELVRDRMAAFPASGEINSRLAEPAAAIARVEAHFAEEA
QAVDRTDGLSMSFADWRFNLRSSNTEPVVRLNVESRGDIPLMEARTRTLLALLNQ

Specific function: Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS O antigen [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=456, Percent_Identity=89.4736842105263, Blast_Score=860, Evalue=0.0,
Organism=Escherichia coli, GI1789566, Length=466, Percent_Identity=27.0386266094421, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 49885; Mature: 49754

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLGGDVRLTSEALKLALAK
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHHH
GLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGD
CHHHCCCCEEEECCCCCCEEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCCCCC
TGLRDVQRLAEAGDFPPVNDAARGSYRQISLRDAYIDHLLAYISVNNLTPLKLVVNSGNG
CCHHHHHHHHHCCCCCCCCHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIPNPLLPECRDDTRKAVIEHGADM
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
GIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKHPGAKIIHDPRLTWNTEAVVTAA
EEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCEEECCCCEECCCEEEEEC
GGTPVMSKTGHAFIKERMRTEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGQ
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
SLGELVRDRMAAFPASGEINSRLAEPAAAIARVEAHFAEEAQAVDRTDGLSMSFADWRFN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHEEEE
LRSSNTEPVVRLNVESRGDIPLMEARTRTLLALLNQ
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLGGDVRLTSEALKLALAK
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHHH
GLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGD
CHHHCCCCEEEECCCCCCEEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCCCCC
TGLRDVQRLAEAGDFPPVNDAARGSYRQISLRDAYIDHLLAYISVNNLTPLKLVVNSGNG
CCHHHHHHHHHCCCCCCCCHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPNGIPNPLLPECRDDTRKAVIEHGADM
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
GIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKHPGAKIIHDPRLTWNTEAVVTAA
EEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCEEECCCCEECCCEEEEEC
GGTPVMSKTGHAFIKERMRTEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGQ
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
SLGELVRDRMAAFPASGEINSRLAEPAAAIARVEAHFAEEAQAVDRTDGLSMSFADWRFN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHEEEE
LRSSNTEPVVRLNVESRGDIPLMEARTRTLLALLNQ
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1383393 [H]