| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is purK [H]
Identifier: 194736649
GI number: 194736649
Start: 583105
End: 584172
Strand: Reverse
Name: purK [H]
Synonym: SeSA_A0578
Alternate gene names: 194736649
Gene position: 584172-583105 (Counterclockwise)
Preceding gene: 194738271
Following gene: 194734279
Centisome position: 12.41
GC content: 58.8
Gene sequence:
>1068_bases ATGAAGCAAGTTTGCGTTCTCGGCAACGGACAACTGGGCCGAATGCTGCGCCAGGCGGGCGAACCGCTGGGTATCGCCGT CTGGCCGGTTGGTCTGGATGCAGAGCCTACTGCTGTTCCGGTACAGCAGAGCGTCATTACCGCAGAGATTGAGCGCTGGC CGGAAACCGCGCTTACCCGCGAGCTGGCACGCCACCCGGCATTCGTCAATCGCGATGTATTTCCGATCATCGCCGACCGT CTGACACAAAAACAGCTTTTCGATAAACTGGGACTCGCGACCGCGCCGTGGCAGCTGCTGACCAGCGCCGACGAGTGGTC CGGCATCTTTGACCGTCTGGGCGAACTGGCGATTATTAAGCGTCGCGTTGGCGGCTACGACGGTCGCGGGCAGTGGCGTC TACGCGCGGACGAAACCGGGCAACTGCCGGATGACTGCTATGGCGAATGTATTGTTGAGCGCGGCATCCATTTTTCCGGC GAAGTGTCGTTAGTCGGCGCGCGCGCTCATGACGGCAGTACCGTGTTTTACCCGCTGACGCACAATTTGCATCAGGACGG CATCTTGCGGACCAGCGTCGCGTTCCCACAGGCGAACGCCGAACAGCAGGAGCAGGCGGAATTAATGCTGTCAGCAATTA TGCAGGCGCTGAACTACGTCGGCGTAATGGCGATGGAATGTTTTATCACGCCGGAAGGCCTGTTAATCAATGAACTGGCG CCGCGCGTGCATAACAGCGGACACTGGACGCAAAATGGCGCCAGCATCAGTCAGTTTGAATTGCATTTGCGCGCGATTAC CGGCCTGCCGTTGCCCGCGCCAGTGATTAACGCCCCGTCGGTGATGATCAATCTGATCGGCAGCGAGCTGAATTACGACT GGCTGAAGCTGCCGCTGGTACATCTGCACTGGTATGATAAAGCGGTACGCCCGGGGCGAAAAGTCGGCCATCTGAATCTG ACCGACAGCGATACGTCACGTCTTAGCGCCACCCTGGAAGCGCTCTCTCCGCTCCTGCCGGGCGAATACGCCAGCGGCAT TATCTGGGCGCAAAGTAAGCTTAAATAA
Upstream 100 bases:
>100_bases TTCTGGCGCAACACGACGCGGAACTGCATCAGCGCATCGCTGACTGGCGCAAAGCGCAAACCGATGAAGTTCTGGAAAAC CCCGATCCGCGGGGGACGCT
Downstream 100 bases:
>100_bases CACATAAAATGCCGGGAGAATGATCTTCCCCTTTCCCGGCTCCTCCCTCAGCGCGTAAAATCTCGCTATTGCTGTTTTGT TTTTCGGGATTACACATGAA
Product: phosphoribosylaminoimidazole carboxylase ATPase subunit
Products: NA
Alternate protein names: N5-CAIR synthase; 5-(carboxyamino)imidazole ribonucleotide synthetase [H]
Number of amino acids: Translated: 355; Mature: 355
Protein sequence:
>355_residues MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADR LTQKQLFDKLGLATAPWQLLTSADEWSGIFDRLGELAIIKRRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSG EVSLVGARAHDGSTVFYPLTHNLHQDGILRTSVAFPQANAEQQEQAELMLSAIMQALNYVGVMAMECFITPEGLLINELA PRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVINAPSVMINLIGSELNYDWLKLPLVHLHWYDKAVRPGRKVGHLNL TDSDTSRLSATLEALSPLLPGEYASGIIWAQSKLK
Sequences:
>Translated_355_residues MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADR LTQKQLFDKLGLATAPWQLLTSADEWSGIFDRLGELAIIKRRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSG EVSLVGARAHDGSTVFYPLTHNLHQDGILRTSVAFPQANAEQQEQAELMLSAIMQALNYVGVMAMECFITPEGLLINELA PRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVINAPSVMINLIGSELNYDWLKLPLVHLHWYDKAVRPGRKVGHLNL TDSDTSRLSATLEALSPLLPGEYASGIIWAQSKLK >Mature_355_residues MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADR LTQKQLFDKLGLATAPWQLLTSADEWSGIFDRLGELAIIKRRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSG EVSLVGARAHDGSTVFYPLTHNLHQDGILRTSVAFPQANAEQQEQAELMLSAIMQALNYVGVMAMECFITPEGLLINELA PRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVINAPSVMINLIGSELNYDWLKLPLVHLHWYDKAVRPGRKVGHLNL TDSDTSRLSATLEALSPLLPGEYASGIIWAQSKLK
Specific function: Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) [H]
COG id: COG0026
COG function: function code F; Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-grasp domain [H]
Homologues:
Organism=Escherichia coli, GI1786733, Length=354, Percent_Identity=88.7005649717514, Blast_Score=624, Evalue=1e-180, Organism=Escherichia coli, GI1788155, Length=303, Percent_Identity=27.0627062706271, Blast_Score=69, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6324702, Length=385, Percent_Identity=28.8311688311688, Blast_Score=140, Evalue=4e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005875 - InterPro: IPR011761 - InterPro: IPR003135 - InterPro: IPR013816 - InterPro: IPR013817 - InterPro: IPR016185 - InterPro: IPR011054 [H]
Pfam domain/function: PF02222 ATP-grasp [H]
EC number: =6.3.4.18 [H]
Molecular weight: Translated: 39138; Mature: 39138
Theoretical pI: Translated: 6.13; Mature: 6.13
Prosite motif: PS50975 ATP_GRASP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQSVITAEIERWPETALTR CCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHH ELARHPAFVNRDVFPIIADRLTQKQLFDKLGLATAPWQLLTSADEWSGIFDRLGELAIIK HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHH RRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSGEVSLVGARAHDGSTVFYPLT HHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEC HNLHQDGILRTSVAFPQANAEQQEQAELMLSAIMQALNYVGVMAMECFITPEGLLINELA CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHH PRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVINAPSVMINLIGSELNYDWLKLPLV HHHCCCCCCCCCCCCHHHHHEEEHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCEE HLHWYDKAVRPGRKVGHLNLTDSDTSRLSATLEALSPLLPGEYASGIIWAQSKLK EEEEHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHCCEEEECCCCC >Mature Secondary Structure MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQSVITAEIERWPETALTR CCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHH ELARHPAFVNRDVFPIIADRLTQKQLFDKLGLATAPWQLLTSADEWSGIFDRLGELAIIK HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHH RRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSGEVSLVGARAHDGSTVFYPLT HHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEC HNLHQDGILRTSVAFPQANAEQQEQAELMLSAIMQALNYVGVMAMECFITPEGLLINELA CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHH PRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVINAPSVMINLIGSELNYDWLKLPLV HHHCCCCCCCCCCCCHHHHHEEEHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCEE HLHWYDKAVRPGRKVGHLNLTDSDTSRLSATLEALSPLLPGEYASGIIWAQSKLK EEEEHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHCCEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2464576; 2644189; 9278503; 1534690; 10569930 [H]