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The map label for this gene is yaaO [H]

Identifier: 194736607

GI number: 194736607

Start: 2073287

End: 2074669

Strand: Reverse

Name: yaaO [H]

Synonym: SeSA_A2182

Alternate gene names: 194736607

Gene position: 2074669-2073287 (Counterclockwise)

Preceding gene: 194737270

Following gene: 194735721

Centisome position: 44.06

GC content: 38.11

Gene sequence:

>1383_bases
ATGAATGCCAAAATTGTTAAAATGAAAGAGAATACACCTGTTCTGGCAGGGCTGAAAAGACTTTGCCATAGGAAAATGTA
TTCATTCCACGCTTTGCCTATTTCGAGTCATGGTCAGAGTGATATTGTTGGCGATACCAGAGAATTTCTTTCTGAATGTC
TGGAGGGGTCAGCAACTGGTGAACTCTTCGATAATTTCTTTTTCCCTCATGGGATTATTGCTGAATCACAAAAATTGACA
GCAAAGCTTTATAATGCTGACGCATCATTTTACATCACCAGTGGAACAAGTACATCTAACCAAATAGCGATCACTGCTCT
TTTTGAAAAGGGTCAACGCATTTTGATTGATAAAAATTGTCACCAATCAATTCATTTTCATGCACAAGCAATTGGTGCTG
AAGTTCGTTACCTTTGTCCTGATTTGCAGACAATGGATCAGGAAATAAGTGCATGGTCATATGCACACTTAGAAAATACA
CTCTTATCATTACAGAATGAAGGTAAAGGGTGTGATATTGTGATTCTGACAGCACAGTCCTATGAGGGCATCATTTATGA
TATTCCACAGGTATTGGCCCATCTTTTGTCAGCTGGTGTGCAGGCTCGAAAATTTTTTATTGATGAGGCATGGGGGAGTC
TGAATTATTTTAGTGAAGATACGAGACAGCTAACAGCAATGAATATAGACTCATTGCTCGAGTTATATCCTGACCTCGAA
GTGATTTGTACACACTCAGCCCATAAATCTCTCTTTTGCCTTCGTCAGGCCTCAATAATTCATTGTCGTGGAAAAAAAGA
ACTGGCAGAGAAGATAGAAACAGCTAAATATAGAATCCATACAACTTCTCCTAGTTACCCAATACTGGCTTCTTTGGATG
CTGCGCAAGCAATGATGTCAGTAAAGGGGGAAATACTTGCTACACATACTCGCGAGTTAGTTCATGAATTTATTATGGGG
GTATCTGATATTGCTGGTCTGGGTGAAAAATCGATTTGCAGGGAGGTATTCAATACACATTGGCATATTCAGTATGACCC
AACCAAAATTATGATCGATGTCAGCGCGTTAGGGACAGGTCAAGAAATAAAAACATTGCTCAGCGAACATGATATATCTC
TAAAGAGATTCATCAATAATTTCATTCTTTTGAATTTTCATATTGGTATTAATAGGGAAGCAATCCGCTGTCTTCTTTCT
TCGCTAACAAAAATTAGCAAAGATAATAAGAACAATAAAGAAGAGAACGCAGTTGCCAATAAATTCATTATATCTTACCC
ACCAGGTGTTCCTCTTGTTTTTCCTGGGGATGTTATTAGCAAAGACGTTAGAAATAAAATAAATGAATGTAAACGGAATG
GCTGCCTAATTATTGCTGCCTGA

Upstream 100 bases:

>100_bases
TATCATTTATGCTGATAGCTGAATCAAAAAATACAAATATTCATCCGGGAAAGCTGATGGCATATTGAAGTTGCATATAA
TATTCTATGAGGAAACTTTA

Downstream 100 bases:

>100_bases
TTATATAATTTATACTATCTAAGGAATATCTAAAATGATTACTCTTCGCAGACTGAATGAAATAGCCATTACTCGAGGTA
ATGATATTTGCATTATTGAT

Product: lysine decarboxylase

Products: putrescine; CO2

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNAKIVKMKENTPVLAGLKRLCHRKMYSFHALPISSHGQSDIVGDTREFLSECLEGSATGELFDNFFFPHGIIAESQKLT
AKLYNADASFYITSGTSTSNQIAITALFEKGQRILIDKNCHQSIHFHAQAIGAEVRYLCPDLQTMDQEISAWSYAHLENT
LLSLQNEGKGCDIVILTAQSYEGIIYDIPQVLAHLLSAGVQARKFFIDEAWGSLNYFSEDTRQLTAMNIDSLLELYPDLE
VICTHSAHKSLFCLRQASIIHCRGKKELAEKIETAKYRIHTTSPSYPILASLDAAQAMMSVKGEILATHTRELVHEFIMG
VSDIAGLGEKSICREVFNTHWHIQYDPTKIMIDVSALGTGQEIKTLLSEHDISLKRFINNFILLNFHIGINREAIRCLLS
SLTKISKDNKNNKEENAVANKFIISYPPGVPLVFPGDVISKDVRNKINECKRNGCLIIAA

Sequences:

>Translated_460_residues
MNAKIVKMKENTPVLAGLKRLCHRKMYSFHALPISSHGQSDIVGDTREFLSECLEGSATGELFDNFFFPHGIIAESQKLT
AKLYNADASFYITSGTSTSNQIAITALFEKGQRILIDKNCHQSIHFHAQAIGAEVRYLCPDLQTMDQEISAWSYAHLENT
LLSLQNEGKGCDIVILTAQSYEGIIYDIPQVLAHLLSAGVQARKFFIDEAWGSLNYFSEDTRQLTAMNIDSLLELYPDLE
VICTHSAHKSLFCLRQASIIHCRGKKELAEKIETAKYRIHTTSPSYPILASLDAAQAMMSVKGEILATHTRELVHEFIMG
VSDIAGLGEKSICREVFNTHWHIQYDPTKIMIDVSALGTGQEIKTLLSEHDISLKRFINNFILLNFHIGINREAIRCLLS
SLTKISKDNKNNKEENAVANKFIISYPPGVPLVFPGDVISKDVRNKINECKRNGCLIIAA
>Mature_460_residues
MNAKIVKMKENTPVLAGLKRLCHRKMYSFHALPISSHGQSDIVGDTREFLSECLEGSATGELFDNFFFPHGIIAESQKLT
AKLYNADASFYITSGTSTSNQIAITALFEKGQRILIDKNCHQSIHFHAQAIGAEVRYLCPDLQTMDQEISAWSYAHLENT
LLSLQNEGKGCDIVILTAQSYEGIIYDIPQVLAHLLSAGVQARKFFIDEAWGSLNYFSEDTRQLTAMNIDSLLELYPDLE
VICTHSAHKSLFCLRQASIIHCRGKKELAEKIETAKYRIHTTSPSYPILASLDAAQAMMSVKGEILATHTRELVHEFIMG
VSDIAGLGEKSICREVFNTHWHIQYDPTKIMIDVSALGTGQEIKTLLSEHDISLKRFINNFILLNFHIGINREAIRCLLS
SLTKISKDNKNNKEENAVANKFIISYPPGVPLVFPGDVISKDVRNKINECKRNGCLIIAA

Specific function: Adc Can Be Found In Two Forms: Biodegradative And Biosynthetic. The Biodegradative Form May Play A Role In Regulating pH By Consuming Proteins. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=278, Percent_Identity=28.4172661870504, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790573, Length=423, Percent_Identity=25.0591016548463, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786909, Length=240, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: 4.1.1.17; 3.5.3.1

Molecular weight: Translated: 51407; Mature: 51407

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKIVKMKENTPVLAGLKRLCHRKMYSFHALPISSHGQSDIVGDTREFLSECLEGSATG
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCH
ELFDNFFFPHGIIAESQKLTAKLYNADASFYITSGTSTSNQIAITALFEKGQRILIDKNC
HHHHHCCCCCCCCCCCHHHHHHEECCCCEEEEECCCCCCCCEEEEEEECCCCEEEEECCC
HQSIHFHAQAIGAEVRYLCPDLQTMDQEISAWSYAHLENTLLSLQNEGKGCDIVILTAQS
CHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
YEGIIYDIPQVLAHLLSAGVQARKFFIDEAWGSLNYFSEDTRQLTAMNIDSLLELYPDLE
CCCCEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCCCE
VICTHSAHKSLFCLRQASIIHCRGKKELAEKIETAKYRIHTTSPSYPILASLDAAQAMMS
EEEECCCHHHHHHHHHCCEEEECCHHHHHHHHHHCEEEEEECCCCCCEEECHHHHHHHHH
VKGEILATHTRELVHEFIMGVSDIAGLGEKSICREVFNTHWHIQYDPTKIMIDVSALGTG
HCCHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCEEEEECCEEEEEEEECCCCC
QEIKTLLSEHDISLKRFINNFILLNFHIGINREAIRCLLSSLTKISKDNKNNKEENAVAN
HHHHHHHHHCCCHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KFIISYPPGVPLVFPGDVISKDVRNKINECKRNGCLIIAA
EEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MNAKIVKMKENTPVLAGLKRLCHRKMYSFHALPISSHGQSDIVGDTREFLSECLEGSATG
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCH
ELFDNFFFPHGIIAESQKLTAKLYNADASFYITSGTSTSNQIAITALFEKGQRILIDKNC
HHHHHCCCCCCCCCCCHHHHHHEECCCCEEEEECCCCCCCCEEEEEEECCCCEEEEECCC
HQSIHFHAQAIGAEVRYLCPDLQTMDQEISAWSYAHLENTLLSLQNEGKGCDIVILTAQS
CHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
YEGIIYDIPQVLAHLLSAGVQARKFFIDEAWGSLNYFSEDTRQLTAMNIDSLLELYPDLE
CCCCEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCCCE
VICTHSAHKSLFCLRQASIIHCRGKKELAEKIETAKYRIHTTSPSYPILASLDAAQAMMS
EEEECCCHHHHHHHHHCCEEEECCHHHHHHHHHHCEEEEEECCCCCCEEECHHHHHHHHH
VKGEILATHTRELVHEFIMGVSDIAGLGEKSICREVFNTHWHIQYDPTKIMIDVSALGTG
HCCHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHCCCEEEEECCEEEEEEEECCCCC
QEIKTLLSEHDISLKRFINNFILLNFHIGINREAIRCLLSSLTKISKDNKNNKEENAVAN
HHHHHHHHHCCCHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
KFIISYPPGVPLVFPGDVISKDVRNKINECKRNGCLIIAA
EEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ornithine

Specific reaction: L-ornithine = putrescine + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]