| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is rfbM [H]
Identifier: 194736193
GI number: 194736193
Start: 2183131
End: 2184570
Strand: Reverse
Name: rfbM [H]
Synonym: SeSA_A2312
Alternate gene names: 194736193
Gene position: 2184570-2183131 (Counterclockwise)
Preceding gene: 194736822
Following gene: 194737984
Centisome position: 46.39
GC content: 40.56
Gene sequence:
>1440_bases ATGTCTGTTCTTCCCGTAATTATGGCTGGCGGCACAGGTAGCCGTTTATGGCCGCTTTCACGCGAATATCATCCGAAGCA GTTTCTAAGCGTTGAAGGTAAACTATCAATGCTGCAAAATACTATAAAGCGATTAGCTTCACTTTCTACAGAAGAACCCG TTGTCATTTGCAATGACAGACACCGTTTCTTAGTCGCTGAACAACTCCGTGAAATTGACAAGTTAGCAAATAATATTATT CTCGAGCCGGTAGGCCGTAATACTGCACCAGCGATCGCTCTTGCCGCGTTTTGTGCGCTCCAGAATGCTGATAATGTTGA TCCTCTTTTGTTGGTTCTTGCTGCAGATCATGTGATCCAGGATGATATAGCTTTTACGAAAGCTGTCAGACGTGCTGAAG AATACGCCGCAAATGGTAAGCTTGTAACTTTTGGTATTGTTCCAACGCATGCTGAAACAGGTTATGGATATATTCGTCGG GGTGAGTTGATAGGAAATGACGCTTATGCAGTGGCTGAATTTGTGGAGAAACCGGATATCGATACCGCCGGTGACTATTT CAAATCAGGGAAATATTACTGGAATAGCGGTATGTTTTTATTTCGTGCAAGCTCTTATTTAAACGAATTAAAGTATTTAT CACCTGAAATTTATAAAGCTTGTGAAAAGGCGGTAGGTCATATAAATCCCGATCTTGATTTTATTCGTATTGATAAAGAA GAGTTTATGTCATGCCCGAGTGATTCTATCGATTATGCAGTTATGGAGCACACACAGCATGCCGTGGTGATACCAATGAG CGCTGGCTGGTCGGATGTGGGATCCTGGTCCTCACTTTGGGATATATCGAATAAAGATCATCAGAGAAATGTTTTAAAAG GAGATATCTTCGCACATGCTTGTAATGATAATTACATTTATTCCGAAGATATGTTTATAAGTGCGATTGGTGTAAGCAAT CTTGTCATTGTTCAAACAACAGACGCTTTACTGGTGGCTAATAAAGATACAGTACAAGATGTTAAAAAAATTGTCGATTA TTTAAAACGGAATGATAGGAACGAATATAAACAACATCAAGAAGTTTTCCGCCCCTGGGGAAAATATAATGTGATTGATA GCGGCAAAAATTACCTCGTTAGATGTATCACTGTTAAGCCGGGTGAGAAATTTGTGGCGCAGATGCATCACCACCGGGCT GAGCATTGGATAGTATTATCCGGGACTGCTCGTGTTACAAAGGGTGAGCAGATTTATATGGTTTCTGAAAATGAATCAAC ATTTATTCCTCCGGATACTATTCACGCGCTGGAAAATCCCGGAATGATCCCCCTGAAGTTAATTGAGATTCAATCAGGTA CCTATCTTGGTGAGGATGATATTATTCGTTTAGAACAACGTTCTGGATTTTCGAAGGAGTGGACTAATGAACGTAGTTAA
Upstream 100 bases:
>100_bases GCATTGGCAATCTTTACCGTTGTCTACATGTCGCTATTTTAGCATGTACAAGAGTTATTGGAATAATATCCAGTATTCTT CGTCAAAAGAGATAAAATAA
Downstream 100 bases:
>100_bases TAATAGCCGTGATGTTATTCATTCATCAGGTATTGTGTTTGGAACGAGTGGGGCTCGCGGTCTTGTAAAAGATTTTACAC CTCAGGTATGTGCTGCTTTT
Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase
Products: NA
Alternate protein names: GDP-mannose pyrophosphorylase; GMP; GMPP; GTP--mannose-1-phosphate guanylyltransferase [H]
Number of amino acids: Translated: 479; Mature: 478
Protein sequence:
>479_residues MSVLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTEEPVVICNDRHRFLVAEQLREIDKLANNII LEPVGRNTAPAIALAAFCALQNADNVDPLLLVLAADHVIQDDIAFTKAVRRAEEYAANGKLVTFGIVPTHAETGYGYIRR GELIGNDAYAVAEFVEKPDIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIRIDKE EFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSN LVIVQTTDALLVANKDTVQDVKKIVDYLKRNDRNEYKQHQEVFRPWGKYNVIDSGKNYLVRCITVKPGEKFVAQMHHHRA EHWIVLSGTARVTKGEQIYMVSENESTFIPPDTIHALENPGMIPLKLIEIQSGTYLGEDDIIRLEQRSGFSKEWTNERS
Sequences:
>Translated_479_residues MSVLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTEEPVVICNDRHRFLVAEQLREIDKLANNII LEPVGRNTAPAIALAAFCALQNADNVDPLLLVLAADHVIQDDIAFTKAVRRAEEYAANGKLVTFGIVPTHAETGYGYIRR GELIGNDAYAVAEFVEKPDIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIRIDKE EFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSN LVIVQTTDALLVANKDTVQDVKKIVDYLKRNDRNEYKQHQEVFRPWGKYNVIDSGKNYLVRCITVKPGEKFVAQMHHHRA EHWIVLSGTARVTKGEQIYMVSENESTFIPPDTIHALENPGMIPLKLIEIQSGTYLGEDDIIRLEQRSGFSKEWTNERS >Mature_478_residues SVLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTEEPVVICNDRHRFLVAEQLREIDKLANNIIL EPVGRNTAPAIALAAFCALQNADNVDPLLLVLAADHVIQDDIAFTKAVRRAEEYAANGKLVTFGIVPTHAETGYGYIRRG ELIGNDAYAVAEFVEKPDIDTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIRIDKEE FMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSNL VIVQTTDALLVANKDTVQDVKKIVDYLKRNDRNEYKQHQEVFRPWGKYNVIDSGKNYLVRCITVKPGEKFVAQMHHHRAE HWIVLSGTARVTKGEQIYMVSENESTFIPPDTIHALENPGMIPLKLIEIQSGTYLGEDDIIRLEQRSGFSKEWTNERS
Specific function: Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen [H]
COG id: COG0836
COG function: function code M; Mannose-1-phosphate guanylyltransferase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]
Homologues:
Organism=Escherichia coli, GI1788362, Length=469, Percent_Identity=59.4882729211087, Blast_Score=580, Evalue=1e-167,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011051 - InterPro: IPR006375 - InterPro: IPR001538 - InterPro: IPR005835 - InterPro: IPR014710 [H]
Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]
EC number: =2.7.7.13 [H]
Molecular weight: Translated: 54057; Mature: 53926
Theoretical pI: Translated: 5.73; Mature: 5.73
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSVLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTEEPVVICNDR CCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCC HRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQNADNVDPLLLVLAADHVIQ CCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH DDIAFTKAVRRAEEYAANGKLVTFGIVPTHAETGYGYIRRGELIGNDAYAVAEFVEKPDI HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECEEECCCHHHHHHHHHCCCC DTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIRIDKE CCCHHHHHCCCEEEECCEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECHH EFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVLKGDIFAHA HHHCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHCCCCCCHHCCCCCCCEEEEE CNDNYIYSEDMFISAIGVSNLVIVQTTDALLVANKDTVQDVKKIVDYLKRNDRNEYKQHQ CCCCEEECCCCEEEEECCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHH EVFRPWGKYNVIDSGKNYLVRCITVKPGEKFVAQMHHHRAEHWIVLSGTARVTKGEQIYM HHHCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCEEEECCCEEEE VSENESTFIPPDTIHALENPGMIPLKLIEIQSGTYLGEDDIIRLEQRSGFSKEWTNERS EECCCCCCCCCHHHHHCCCCCCCEEEEEEEECCCEECCCCEEEECCCCCCCCCCCCCCC >Mature Secondary Structure SVLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKRLASLSTEEPVVICNDR CCEEEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCC HRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQNADNVDPLLLVLAADHVIQ CCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH DDIAFTKAVRRAEEYAANGKLVTFGIVPTHAETGYGYIRRGELIGNDAYAVAEFVEKPDI HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECEEECCCHHHHHHHHHCCCC DTAGDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIYKACEKAVGHINPDLDFIRIDKE CCCHHHHHCCCEEEECCEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECHH EFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSWSSLWDISNKDHQRNVLKGDIFAHA HHHCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHCCCCCCHHCCCCCCCEEEEE CNDNYIYSEDMFISAIGVSNLVIVQTTDALLVANKDTVQDVKKIVDYLKRNDRNEYKQHQ CCCCEEECCCCEEEEECCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHH EVFRPWGKYNVIDSGKNYLVRCITVKPGEKFVAQMHHHRAEHWIVLSGTARVTKGEQIYM HHHCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCEEEECCCEEEE VSENESTFIPPDTIHALENPGMIPLKLIEIQSGTYLGEDDIIRLEQRSGFSKEWTNERS EECCCCCCCCCHHHHHCCCCCCCEEEEEEEECCCEECCCCEEEECCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1710759; 11677609 [H]