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The map label for this gene is ccmF [H]

Identifier: 194735440

GI number: 194735440

Start: 4410387

End: 4412123

Strand: Direct

Name: ccmF [H]

Synonym: SeSA_A4533

Alternate gene names: 194735440

Gene position: 4410387-4412123 (Clockwise)

Preceding gene: 194735175

Following gene: 194737153

Centisome position: 93.66

GC content: 59.36

Gene sequence:

>1737_bases
TTGCATAATCTGGACATCTTCCTTCCTGAAGCCGGATTTCTGGCGCTGTTGTTGAGTCTCGGGGTCAACGTGTTGACCCC
GCTGGCGACGTGGTGCGGGATGGGGCAGCACTGGCGTGGCGTCATGCGCCTGACGACCTGCGGCGCGTGGACGGCGTTCA
CGCTGCTGCTACTGGCGTTTGCGATTCTGGTTAGCTGTTTTCTGACCAGCGATTTTTCGGTCGTTTATGTTGCGCAGCAT
AGCCATAGTCAGTTGTCATGGGGACTGAAACTGGCGGCGGTATGGGGCGGTCATGAAGGCTCGCTCCTGCTGTGGGCGCT
GCTTCTTTCGGGGTGGACGGCGCTATTCGCCTGGCGCTCCCGGCATGAATCTGACGCGCTTTTTCCGCTGACCCTGAGCA
TCTTGTCCCTCATTATGGCCTCGCTGCTGCTATTTATTGTGCTGTGGTCCGATCCGTTCCTGCGTATTTTCCCTCCCGCC
ATGGAAGGGCGCGACCTTAATCCCATGCTGCAACATCTGGGGCTGATCTTACATCCGCCTCTGCTCTATCTGGGTTATGG
CGGCCTGATGACCGCGGCGAGCGTAGCGCTGGCTTCGCTACTGTGCGGCGGCTTTAACGCGGCAACCGCCTGGGTGTGCT
GGCGCTGGGCGTTACCCGGCTGGTGCGCTCTGACGCTGGGGATCATTCTCGGATCGTGGTGGGCGTATTGCGAACTGGGC
TGGGGCGGCTGGTGGTTCTGGGACCCGGTGGAAAATGCCTCGTTGTTGCCGTGGCTTGCCGCCAGCGCCTTGCTGCACAG
TCTGTATGTCAGCCGCCAGCGCGGGAGCTTCCGTCACTGGTCGTTGCTGCTGGCGATACTGACGCTGATCCTCTCGTTGC
TGGGAACGCTGATTGTGCGTTCCGGCATTCTTGTTTCGGTACATGCCTTTGCGCTGGATAACGTGCGCGCGGTGCCGCTG
TTTACCCTTTTTGCCGCGTTAAGTCTGGCATCGCTTGCTCTGTACGGCTGGCGGGCGCGGGAGCCGTATCCGGCGACGCG
TTTGGACGGCGGAAAGTGCGAAACGCTCATTCTGGCGACGTTGCTGCTCTTTAGCGCCGTCTTGTTGATCGTGCTGGTCG
GGACGCTCTACCCCATGATTTATGGTTTGATGGGCTGGGGAAGGCTTTCGGTGGGCGCGCCCTATTTTAATCGCGTCACG
CTGCCGTTTGGTCTGCTGATGCTGGTGGTTATCGTACTGGCGACAATCAGAAGCCGCAAAGTCTCTGTGCATCGTCAGCT
TCCGGCATTGCTGGCGCATACGGGCGTATTTATCTTCGCCGCCGGGATCATGGTTTCCAGCGGTAGTCGGCATGAAATCA
GCCTTAACCTCAGCCCCAGTCAGCAGGTAGTACTGGCGGGCTATACCTTTCGTTTCGAGCGTCTGGATCTGGAGGCCAAA
GGCAACTACACCAGTGAAAAAGCGCGGATCACGTTGTGGCGGAATGAAAAACGCATTGGCAGCCTGCAGCCTGAAAGGCG
CTTCTATGCCGCGCGTCGTCAACAGATGATGGAGCCGGGGATTCACTGGAACCTGCTACATGACTGGTACGCGGTGATGG
GCGAAAAAACCGGACCGGATCGTTACGCCATGCGCTTATACGTGCAGACCGGCGTGCGCTGGATCTGGGGTGGGGGATTG
TTGATGGTGTGTGGCGCGCTGCTGAGCGGATGGCGGGGGAGGAAGCGTGATGCGTAA

Upstream 100 bases:

>100_bases
CGTAGCGTCACGTTTCACGGCGTGCTGGCCGTTTGCGGCGCCAGTTTGACCGGCGTGCTGCTGCTGCGCTTTTTCATTCT
TTATGCGGGACAGCTAACGG

Downstream 100 bases:

>100_bases
ATTACTCACAGCGTTGCCGGATGGCGGCGTAAACGCCTTATCCGGCCTACAGGATGCGCAAACCGTAGGTCGGATAAGCG
TAGCGCCATCCGGCAGAAAG

Product: heme lyase subunit NrfE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMGQHWRGVMRLTTCGAWTAFTLLLLAFAILVSCFLTSDFSVVYVAQH
SHSQLSWGLKLAAVWGGHEGSLLLWALLLSGWTALFAWRSRHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPA
MEGRDLNPMLQHLGLILHPPLLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWALPGWCALTLGIILGSWWAYCELG
WGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGSFRHWSLLLAILTLILSLLGTLIVRSGILVSVHAFALDNVRAVPL
FTLFAALSLASLALYGWRAREPYPATRLDGGKCETLILATLLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVGAPYFNRVT
LPFGLLMLVVIVLATIRSRKVSVHRQLPALLAHTGVFIFAAGIMVSSGSRHEISLNLSPSQQVVLAGYTFRFERLDLEAK
GNYTSEKARITLWRNEKRIGSLQPERRFYAARRQQMMEPGIHWNLLHDWYAVMGEKTGPDRYAMRLYVQTGVRWIWGGGL
LMVCGALLSGWRGRKRDA

Sequences:

>Translated_578_residues
MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMGQHWRGVMRLTTCGAWTAFTLLLLAFAILVSCFLTSDFSVVYVAQH
SHSQLSWGLKLAAVWGGHEGSLLLWALLLSGWTALFAWRSRHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPA
MEGRDLNPMLQHLGLILHPPLLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWALPGWCALTLGIILGSWWAYCELG
WGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGSFRHWSLLLAILTLILSLLGTLIVRSGILVSVHAFALDNVRAVPL
FTLFAALSLASLALYGWRAREPYPATRLDGGKCETLILATLLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVGAPYFNRVT
LPFGLLMLVVIVLATIRSRKVSVHRQLPALLAHTGVFIFAAGIMVSSGSRHEISLNLSPSQQVVLAGYTFRFERLDLEAK
GNYTSEKARITLWRNEKRIGSLQPERRFYAARRQQMMEPGIHWNLLHDWYAVMGEKTGPDRYAMRLYVQTGVRWIWGGGL
LMVCGALLSGWRGRKRDA
>Mature_578_residues
MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMGQHWRGVMRLTTCGAWTAFTLLLLAFAILVSCFLTSDFSVVYVAQH
SHSQLSWGLKLAAVWGGHEGSLLLWALLLSGWTALFAWRSRHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPA
MEGRDLNPMLQHLGLILHPPLLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWALPGWCALTLGIILGSWWAYCELG
WGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGSFRHWSLLLAILTLILSLLGTLIVRSGILVSVHAFALDNVRAVPL
FTLFAALSLASLALYGWRAREPYPATRLDGGKCETLILATLLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVGAPYFNRVT
LPFGLLMLVVIVLATIRSRKVSVHRQLPALLAHTGVFIFAAGIMVSSGSRHEISLNLSPSQQVVLAGYTFRFERLDLEAK
GNYTSEKARITLWRNEKRIGSLQPERRFYAARRQQMMEPGIHWNLLHDWYAVMGEKTGPDRYAMRLYVQTGVRWIWGGGL
LMVCGALLSGWRGRKRDA

Specific function: May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1790511, Length=554, Percent_Identity=77.6173285198556, Blast_Score=788, Evalue=0.0,
Organism=Escherichia coli, GI1788524, Length=636, Percent_Identity=37.4213836477987, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568
- InterPro:   IPR003570 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 64303; Mature: 64303

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMGQHWRGVMRLTTCGAWTAFTLLLLAF
CCCCEEEECCHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
AILVSCFLTSDFSVVYVAQHSHSQLSWGLKLAAVWGGHEGSLLLWALLLSGWTALFAWRS
HHHHHHHHCCCCCEEEEEECCCCHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPAMEGRDLNPMLQHLGLILHPP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHCHHHHCCH
LLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWALPGWCALTLGIILGSWWAYCELG
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHEEEC
WGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGSFRHWSLLLAILTLILSLLGTLIVR
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGILVSVHAFALDNVRAVPLFTLFAALSLASLALYGWRAREPYPATRLDGGKCETLILAT
CCHHEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
LLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVGAPYFNRVTLPFGLLMLVVIVLATIRSRK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSVHRQLPALLAHTGVFIFAAGIMVSSGSRHEISLNLSPSQQVVLAGYTFRFERLDLEAK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEEEEC
GNYTSEKARITLWRNEKRIGSLQPERRFYAARRQQMMEPGIHWNLLHDWYAVMGEKTGPD
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
RYAMRLYVQTGVRWIWGGGLLMVCGALLSGWRGRKRDA
HHHHEEEHHHCCEEEECCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMGQHWRGVMRLTTCGAWTAFTLLLLAF
CCCCEEEECCHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
AILVSCFLTSDFSVVYVAQHSHSQLSWGLKLAAVWGGHEGSLLLWALLLSGWTALFAWRS
HHHHHHHHCCCCCEEEEEECCCCHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPAMEGRDLNPMLQHLGLILHPP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHCHHHHCCH
LLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWALPGWCALTLGIILGSWWAYCELG
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHEEEC
WGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGSFRHWSLLLAILTLILSLLGTLIVR
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGILVSVHAFALDNVRAVPLFTLFAALSLASLALYGWRAREPYPATRLDGGKCETLILAT
CCHHEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
LLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVGAPYFNRVTLPFGLLMLVVIVLATIRSRK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSVHRQLPALLAHTGVFIFAAGIMVSSGSRHEISLNLSPSQQVVLAGYTFRFERLDLEAK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEEEEC
GNYTSEKARITLWRNEKRIGSLQPERRFYAARRQQMMEPGIHWNLLHDWYAVMGEKTGPD
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
RYAMRLYVQTGVRWIWGGGLLMVCGALLSGWRGRKRDA
HHHHEEEHHHCCEEEECCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8057835; 8265357; 9278503 [H]