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The map label for this gene is argE [H]

Identifier: 194735342

GI number: 194735342

Start: 4205486

End: 4206637

Strand: Reverse

Name: argE [H]

Synonym: SeSA_A4330

Alternate gene names: 194735342

Gene position: 4206637-4205486 (Counterclockwise)

Preceding gene: 194734506

Following gene: 194737003

Centisome position: 89.33

GC content: 53.73

Gene sequence:

>1152_bases
ATGAAAAACGTTTTACCGCCATTTATCGAGATTTACCGCGCTTTGATTGCCACACCGTCGATAAGCGCAACCGAAGAATC
CCTGGATCAAAGTAATGCGTCTTTAATCACTTTGCTTGCAGGCTGGTTCAGCGATCTTGGTTTCAACGTAGAGGTTCAAC
CGGTTCCAGGGACGCGAAACAAATTTAATATGCTCGCCAGCACCGGACATGGCGCGGGCGGTTTGCTGCTGACCGGCCAT
ACCGACACGGTTCCCTTTGATGACGGACGCTGGACGCGCGACCCGTTCACGCTGACCGAGCACGACAATAAGCTCTATGG
TCTGGGCACTGCGGATATGAAAGGCTTCTTCGCTTTTATTCTGGACGCGCTACGTGACGTTGACGTCACAAAGTTGAAAA
AGCCGCTCTACATTCTGGCGACCGCCGATGAAGAGACCAGCATGGCGGGGGCGCGTTATTTTTCCGAAACCACGGCATTA
CGTCCGGACTGCGCGATCATTGGCGAACCGACGTCGTTGCAACCGATACGCGCGCACAAAGGGCATATCTCTAATGTCGT
TCGCGTCCTGGGGCAGTCCGGTCATTCCAGCGACCCGGCGCGTGGGGTTAACGCCATTGAACTGATGCACGATGCGATTG
GCCATATCATGCAACTGCGTGACTCGCTGAAAGCGCGGTATCACTACGAGGCGTTTACCGTTCCGTATCCAACGCTGAAT
CTGGGCCATATCCACGGCGGCGATGCCTCAAACCGTATCTGCGCCTGCTGCGAATTGCATATGGATATTCGTCCACTGCC
GGGCATGACGTTAAACGACCTTAATGGACTGCTTAACGACGCGCTGGCCCCGGTAAGCGAACGCTGGCCGGGCCGCCTGA
CGGTGGCGGAATTACATCCGCCGATTCCAGGTTACGAGTGTCCACCGGACCACCAACTGGTTGAAGTAGTAGAAAAACTG
TTGGGAACAAAAACCGACGTGGTGAACTACTGTACTGAAGCGCCGTTTATGCAGACATTATGCCCAACGCTGGTGCTTGG
TCCGGGCTCAATTAATCAGGCGCATCAGCCGGATGAATATCTCGAAACGCGTTTTATTAAGCCAACCCGGGAATTGATTA
CCCAGGTAGTACACCATTTTTGCTGGCATTAA

Upstream 100 bases:

>100_bases
CGTATTCAACATCGGGTTCCTTTATGCTCAACGTTAATGTATTTTTATTCATAATTAATGCATGAATATTGATACTATCA
TGACCTGAGGTGTGTCAACA

Downstream 100 bases:

>100_bases
TGCATATTGCCCGGTGACACGATGTTTACCGGGCCTCCCCCGTCTTGTAGGCCGGATAAGCGCAGCGCCATCCGGCATCT
CTACGCCACATGTTCATAAG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGH
TDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTAL
RPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKL
LGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH

Sequences:

>Translated_383_residues
MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGH
TDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTAL
RPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKL
LGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH
>Mature_383_residues
MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGH
TDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTAL
RPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKL
LGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=383, Percent_Identity=93.4725848563969, Blast_Score=755, Evalue=0.0,
Organism=Escherichia coli, GI1789236, Length=385, Percent_Identity=26.7532467532467, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788816, Length=259, Percent_Identity=28.957528957529, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17551016, Length=387, Percent_Identity=25.0645994832041, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42203; Mature: 42203

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRN
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
KFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFI
HHHHHEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHH
LDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHH
GHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLN
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCE
LGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHP
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEEECCC
PIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHEEECCCCCCCCCCCHHH
LETRFIKPTRELITQVVHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRN
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
KFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFI
HHHHHEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHH
LDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHH
GHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLN
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCE
LGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHP
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEEECCC
PIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHEEECCCCCCCCCCCHHH
LETRFIKPTRELITQVVHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA