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The map label for this gene is iraP

Identifier: 194735119

GI number: 194735119

Start: 449952

End: 450212

Strand: Direct

Name: iraP

Synonym: SeSA_A0437

Alternate gene names: 194735119

Gene position: 449952-450212 (Clockwise)

Preceding gene: 194736766

Following gene: 194736123

Centisome position: 9.55

GC content: 46.74

Gene sequence:

>261_bases
ATGAAAAATCTCATAGCAGAGTTGTTGCTTAAGCTAGCCCAAAAAGAAGAAGAGTCGAAAGAACTGGTTGCTCAGGTAGA
AGCGTTAGAGATTATCGTCACAGCAATGTTACGTAACATGGCGCAAAACGAGCAGGAGATGTTGATACGTCAGGTAGAGG
GGGCACTTGAAGGCGTAAAGCCGGATGCCAGCGTTCCTGATCACGATACGGAATTGCTGCGCCAATATGTAAAAAAGTTG
CTGAGACACCCCCGGCACTAA

Upstream 100 bases:

>100_bases
GTAAAGTTCTTCCTGTATCATAAAAATAGTACTTTCAGCCTCTAGGCAGTGGTTCTTCATAGTGATAACGTCACCCTGGA
ACTAATAAGGAAATATGGTC

Downstream 100 bases:

>100_bases
TCGTATTTAAAACAACACAGTTGTTATAACGTTACTTTTATAAAATAGCCCTGGCCGCTTCGTTTTTATTTTGCTCTGTA
TTAACCAGAAGAAAATAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 86

Protein sequence:

>86_residues
MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKL
LRHPRH

Sequences:

>Translated_86_residues
MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKL
LRHPRH
>Mature_86_residues
MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKL
LRHPRH

Specific function: Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS s

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iraP family

Homologues:

Organism=Escherichia coli, GI1786581, Length=86, Percent_Identity=84.8837209302326, Blast_Score=144, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IRAP_SALA4 (B5EWR4)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002145363.1
- PRIDE:   B5EWR4
- GeneID:   6792589
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B0419
- HOGENOM:   HBG416557
- OMA:   HMEHDAQ
- ProtClustDB:   PRK10244
- GO:   GO:0005737
- HAMAP:   MF_01198
- InterPro:   IPR019732

Pfam domain/function: PF10796 Anti-adapt_IraP

EC number: NA

Molecular weight: Translated: 9883; Mature: 9883

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVK
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
PDASVPDHDTELLRQYVKKLLRHPRH
CCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVK
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
PDASVPDHDTELLRQYVKKLLRHPRH
CCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA