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The map label for this gene is citC [H]

Identifier: 194734877

GI number: 194734877

Start: 68646

End: 69677

Strand: Direct

Name: citC [H]

Synonym: SeSA_A0064

Alternate gene names: 194734877

Gene position: 68646-69677 (Clockwise)

Preceding gene: 194734027

Following gene: 194734690

Centisome position: 1.46

GC content: 53.59

Gene sequence:

>1032_bases
GTGAATCTGATATTTAAACGCATTTATTTGCAAAAGGATGTATTGCGTCGCGAGTCGGTCGCCATGTTTCTGGAGGGCGA
GGGACTCGCCCTGGAAGACGATTGTGAAATCGCGGTATGCGCATATTGGCAGGGTGAGATAGTTGGATGCGGCTCGCTGG
TCGGGAACGTACTGAAATGCATCGCTGTTTCCCCAGTTTTACAAGGGGAAGGGCTCAGCCTCAAACTGCTGACTGAGTTG
CTTACATTGGCCTACGAGTTAAACCGCAGCGAGCTTTTCCTGTTCACTAAGCCGCAAAATCGGTTGCTGTTTTCTGGCGC
GGGGTTTTGGCCCATTGCGCAGGCAGGTCAGCTGGCGGTGTTAATGGAGAACAGCAGTGAACGGTTAGCGCGCTTTTGTC
GCCAACTGGCGCTTTATCGTCAACCGGGAAAAACGATCGGCGCCATCGTCATGAACGCCAATCCGTTTACATTGGGCCAC
CGTTATCTGGTGGAGCAAGCGGCTGCGGCCTGTGACTGGCTGCATCTGTTTGTGGTCAAAGAAGATGCTTCATTTTTTTC
CTATACCGACCGTTGGGCGCTGATCGAACAAGGAATCGCGGGCATTGACAACGTCACGTTGCATTCCGGCTCCGCTTATA
TGATCTCGCGTGCGACGTTTCCCGGCTATTTCCTCAAAGAAAAAGGGGTTGTGGACGACTGCCATTGCCAGATCGATCTG
CAACTCTTCCGTGAACATCTGGCTCCAGCTCTGGGGATTACCCATCGTTTTGTCGGCAGTGAACCGTTTTGTCCTCTGAC
CTGTGCCTATAACCAGCGAATGCACGACATTTTACACGATCCGAAGCGCAGCGGCCCGGTTATTGAGGTCGTCGAGCTGG
CGCGGGTGGAGAAAAACGGCACGGCTATTTCCGCCTCTCGCGTCAGAAAACTGTATAGCGAACGTAATTGGCCGGCGATA
AGCGCGCTGGTGCCTGCTGGTACCCTGGCATATCTGCAGCGGCATGCCGCCAGACACACTGAAACCATATGA

Upstream 100 bases:

>100_bases
GGTCATAAAGGCAGCGGGGAAAGTGTGATGTCTATTCCAGACGAATAATATAAACACTGGCGAAATATGCGGCGTTATTT
GCTGACGGATGCTGAATAGA

Downstream 100 bases:

>100_bases
CGTAACACCGTTAACAAGGAACATAACTAATGAAAATCATTAAAGATGCCCTGGCAGGCACGCTGGAATCCAGCGATGTG
ATGATCAGGATTGGTCCATC

Product: [citrate (pro-3S)-lyase] ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNLIFKRIYLQKDVLRRESVAMFLEGEGLALEDDCEIAVCAYWQGEIVGCGSLVGNVLKCIAVSPVLQGEGLSLKLLTEL
LTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGQLAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGH
RYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHCQIDL
QLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERNWPAI
SALVPAGTLAYLQRHAARHTETI

Sequences:

>Translated_343_residues
MNLIFKRIYLQKDVLRRESVAMFLEGEGLALEDDCEIAVCAYWQGEIVGCGSLVGNVLKCIAVSPVLQGEGLSLKLLTEL
LTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGQLAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGH
RYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHCQIDL
QLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERNWPAI
SALVPAGTLAYLQRHAARHTETI
>Mature_343_residues
MNLIFKRIYLQKDVLRRESVAMFLEGEGLALEDDCEIAVCAYWQGEIVGCGSLVGNVLKCIAVSPVLQGEGLSLKLLTEL
LTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGQLAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGH
RYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHCQIDL
QLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERNWPAI
SALVPAGTLAYLQRHAARHTETI

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=332, Percent_Identity=49.3975903614458, Blast_Score=339, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 38262; Mature: 38262

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIFKRIYLQKDVLRRESVAMFLEGEGLALEDDCEIAVCAYWQGEIVGCGSLVGNVLKC
CCHHHHHHHHHHHHHHHHCEEEEECCCCCEECCCCCEEEEEEECCCEEEHHHHHHHHHHH
IAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGQLAV
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCCCEEE
LMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGHRYLVEQAAAACDWLHLFVVK
EEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEEE
EDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHCQIDL
CCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCEEEECCCCCCCCEEEEEH
QLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNG
HHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TAISASRVRKLYSERNWPAISALVPAGTLAYLQRHAARHTETI
CEECHHHHHHHHHCCCCCEEEHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLIFKRIYLQKDVLRRESVAMFLEGEGLALEDDCEIAVCAYWQGEIVGCGSLVGNVLKC
CCHHHHHHHHHHHHHHHHCEEEEECCCCCEECCCCCEEEEEEECCCEEEHHHHHHHHHHH
IAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGQLAV
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCCCEEE
LMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGHRYLVEQAAAACDWLHLFVVK
EEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEEE
EDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHCQIDL
CCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCEEEECCCCCCCCEEEEEH
QLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNG
HHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TAISASRVRKLYSERNWPAISALVPAGTLAYLQRHAARHTETI
CEECHHHHHHHHHCCCCCEEEHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7830578 [H]