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The map label for this gene is cutA [H]

Identifier: 194734784

GI number: 194734784

Start: 4468949

End: 4469296

Strand: Reverse

Name: cutA [H]

Synonym: SeSA_A4594

Alternate gene names: 194734784

Gene position: 4469296-4468949 (Counterclockwise)

Preceding gene: 194734295

Following gene: 194737290

Centisome position: 94.91

GC content: 52.87

Gene sequence:

>348_bases
ATGCTTGATGTTAAGAGTCAGGATATTTCCATCCCCGAGGCCGTTGTGGTGCTTTGTACCGCCCCGGATGAAGCTACCGC
CCAGGATCTGGCCGCCAAAGTGCTGGCGGAAAAACTGGCCGCCTGCGCCACCCTCCTCCCCGGCGCGACATCGCTGTACT
ACTGGGAAGGCAAACTGGAGCAGGAGTATGAAGTTCAAATGATCTTAAAGACCACCGTTTCACATCAGCAAGCGCTTATC
GACTGCCTGAAGTCTCATCACCCGTATCAAACGCCTGAACTTCTGGTTTTACCTGTTACTCACGGAGATACTGATTACCT
CTCATGGCTCAACGCATCTTTACGCTGA

Upstream 100 bases:

>100_bases
ATCACGCCCCGCATTCTCCCGCCCTTTGACTAACATCCTGCCCTCGTCCGTTGTATAGTGACCGTTCACTTGCGGGTCTT
TTTGTTCTTTCGAGGTGTTT

Downstream 100 bases:

>100_bases
TCCTGCTGCTGTGCAGCACATCCGCCTTCGCCGGATTATTCGACGCGCCGGGTCGCTCGCAGTTCGTCCCTGCCGACCGG
GCGTTTGTTTTTGATTTTCA

Product: divalent-cation tolerance protein CutA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALI
DCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR

Sequences:

>Translated_115_residues
MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALI
DCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
>Mature_115_residues
MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALI
DCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=94, Percent_Identity=42.5531914893617, Blast_Score=91, Evalue=1e-19,
Organism=Homo sapiens, GI62526022, Length=94, Percent_Identity=42.5531914893617, Blast_Score=91, Evalue=1e-19,
Organism=Homo sapiens, GI7706244, Length=94, Percent_Identity=42.5531914893617, Blast_Score=91, Evalue=1e-19,
Organism=Homo sapiens, GI62526026, Length=94, Percent_Identity=42.5531914893617, Blast_Score=91, Evalue=1e-19,
Organism=Homo sapiens, GI62198241, Length=94, Percent_Identity=42.5531914893617, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790579, Length=115, Percent_Identity=89.5652173913044, Blast_Score=207, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI32565476, Length=96, Percent_Identity=37.5, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641937, Length=95, Percent_Identity=32.6315789473684, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12681; Mature: 12681

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLE
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLE
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA