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The map label for this gene is rfbH

Identifier: 194734744

GI number: 194734744

Start: 2192468

End: 2193781

Strand: Reverse

Name: rfbH

Synonym: SeSA_A2323

Alternate gene names: 194734744

Gene position: 2193781-2192468 (Counterclockwise)

Preceding gene: 194737521

Following gene: 194734104

Centisome position: 46.59

GC content: 44.6

Gene sequence:

>1314_bases
ATGACAGCAAATAACCTGCGTGAGCAAATCTCTCAGCTTGTCGCTCAGTATGCGAATGAGGCATTGAGCCCGAAACCTTT
TGTTGCAGGTACAAGCGTTGTGCCTCCTTCCGGGAAGGTTATTGGTGCCAAAGAGTTACAATTGATGGTTGAGGCGTCTC
TTGATGGATGGCTAACTACTGGTCGTTTCAATGATGCCTTTGAGAAAAAACTTGGGGAATTTATTGGGGTTCCTCATGTT
TTAACGACTACATCTGGCTCTTCGGCAAACTTGCTGGCACTGACTGCGCTGACTTCCCCAAAATTAGGCGAGCGTGCTCT
CAAACCTGGTGATGAGGTTATTACTGTCGCTGCTGGCTTCCCGACTACAGTTAACCCGGCGATCCAGAATGGTTTAATAC
CGGTATTCGTGGATGTTGATATCCCGACATATAATATCGATGCCTCTCTCATTGAAGCTGCAGTTACTGAGAAATCAAAA
GCGATAATGATCGCTCATACACTCGGTAATGCATTTAACCTGAGTGAAGTTCGTCGGATTGCCGATAAATATAACTTATG
GTTGATTGAAGACTGCTGTGATGCCCTTGGGACGACTTATGAAGGCCAGATGGTAGGTACCTTTGGTGACATCGGAACCG
TTAGTTTTTATCCGGCTCACCATATCACAATGGGTGAAGGCGGTGCTGTATTCACCAAGTCAGGTGAACTGAAGAAAATT
ATTGAGTCGTTCCGTGACTGGGGCCGGGATTGTTATTGTGCGCCAGGATGCGATAACACCTGCGGTAAACGTTTTGGTCA
GCAATTGGGATCTCTTCCTCAAGGCTATGATCACAAATATACTTATTCCCACCTCGGATATAATCTCAAAATCACGGACA
TGCAGGCAGCATGTGGTCTGGCTCAGTTGGAGCGCGTAGAAGAGTTTGTAGAGCAGCGTAAAGCTAACTTTTCCTATCTG
AAACAGGGCTTGCAATCTTGCACTGAATTCCTCGAATTACCAGAAGCAACAGAGAAATCAGACCCATCCTGGTTTGGCTT
CCCTATCACCCTGAAAGAAACTAGCGGTGTTAACCGTGTCGAACTGGTGAAATTCCTTGATGAAGCAAAAATCGGTACAC
GTTTACTGTTTGCTGGAAATCTGATTCGCCAACCGTATTTTGCTAATGTGAAATATCGTGTAGTGGGTGAGTTGACAAAT
ACCGACCGTATAATGAATCAAACGTTCTGGATTGGTATTTATCCAGGCTTGACTACAGAGCATTTAGATTATGTAGTTAG
CAAGTTTGAAGAGTTCTTTGGTTTAAATTTCTAA

Upstream 100 bases:

>100_bases
GGATTCGCGGCGAAGATATGTTGATTTGTTCAAAGCGTGAAATCAGCGACTATATGTCTGCAACTACTCGTTAAGAAAAT
AAGTTTAAGGAATCAAAGTA

Downstream 100 bases:

>100_bases
TTTAATCTATTCTATCTGGTGATTGCGATGACCTTTTTGAAAGAATATGTAATTGTCAGTGGGGCTTCCGGCTTTATTGG
TAAGCATTTACTCGAAGCTC

Product: lipopolysaccharide biosynthesis protein RfbH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTANNLREQISQLVAQYANEALSPKPFVAGTSVVPPSGKVIGAKELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHV
LTTTSGSSANLLALTALTSPKLGERALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSK
AIMIAHTLGNAFNLSEVRRIADKYNLWLIEDCCDALGTTYEGQMVGTFGDIGTVSFYPAHHITMGEGGAVFTKSGELKKI
IESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGYDHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVEQRKANFSYL
KQGLQSCTEFLELPEATEKSDPSWFGFPITLKETSGVNRVELVKFLDEAKIGTRLLFAGNLIRQPYFANVKYRVVGELTN
TDRIMNQTFWIGIYPGLTTEHLDYVVSKFEEFFGLNF

Sequences:

>Translated_437_residues
MTANNLREQISQLVAQYANEALSPKPFVAGTSVVPPSGKVIGAKELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHV
LTTTSGSSANLLALTALTSPKLGERALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSK
AIMIAHTLGNAFNLSEVRRIADKYNLWLIEDCCDALGTTYEGQMVGTFGDIGTVSFYPAHHITMGEGGAVFTKSGELKKI
IESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGYDHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVEQRKANFSYL
KQGLQSCTEFLELPEATEKSDPSWFGFPITLKETSGVNRVELVKFLDEAKIGTRLLFAGNLIRQPYFANVKYRVVGELTN
TDRIMNQTFWIGIYPGLTTEHLDYVVSKFEEFFGLNF
>Mature_436_residues
TANNLREQISQLVAQYANEALSPKPFVAGTSVVPPSGKVIGAKELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHVL
TTTSGSSANLLALTALTSPKLGERALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSKA
IMIAHTLGNAFNLSEVRRIADKYNLWLIEDCCDALGTTYEGQMVGTFGDIGTVSFYPAHHITMGEGGAVFTKSGELKKII
ESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGYDHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVEQRKANFSYLK
QGLQSCTEFLELPEATEKSDPSWFGFPITLKETSGVNRVELVKFLDEAKIGTRLLFAGNLIRQPYFANVKYRVVGELTNT
DRIMNQTFWIGIYPGLTTEHLDYVVSKFEEFFGLNF

Specific function: Unknown

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family

Homologues:

Organism=Escherichia coli, GI145693159, Length=404, Percent_Identity=28.7128712871287, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI2367285, Length=343, Percent_Identity=30.0291545189504, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RFBH_SALTY (P26398)

Other databases:

- EMBL:   X56793
- EMBL:   AE006468
- PIR:   S15306
- RefSeq:   NP_461035.1
- ProteinModelPortal:   P26398
- SMR:   P26398
- PRIDE:   P26398
- GeneID:   1253611
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2090
- HOGENOM:   HBG660897
- OMA:   HKYVYSH
- ProtClustDB:   PRK15407
- BioCyc:   STYP99287:STM2090-MONOMER
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000390

Pfam domain/function: PF01041 DegT_DnrJ_EryC1; SSF53383 PyrdxlP-dep_Trfase_major

EC number: NA

Molecular weight: Translated: 48104; Mature: 47973

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANNLREQISQLVAQYANEALSPKPFVAGTSVVPPSGKVIGAKELQLMVEASLDGWLTT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECHHHHEEEEEECCCCCEEC
GRFNDAFEKKLGEFIGVPHVLTTTSGSSANLLALTALTSPKLGERALKPGDEVITVAAGF
CCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCHHHCCCCCCEEEEEECC
PTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSKAIMIAHTLGNAFNLSEVRRI
CCCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
ADKYNLWLIEDCCDALGTTYEGQMVGTFGDIGTVSFYPAHHITMGEGGAVFTKSGELKKI
HHHHCEEEHHHHHHHHCCCCCCEEEECCCCCCCEEEECCEEEEECCCCEEEECCCHHHHH
IESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGYDHKYTYSHLGYNLKITDMQAACGL
HHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEHHHCCEEEEEECHHHHHHH
AQLERVEEFVEQRKANFSYLKQGLQSCTEFLELPEATEKSDPSWFGFPITLKETSGVNRV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCHH
ELVKFLDEAKIGTRLLFAGNLIRQPYFANVKYRVVGELTNTDRIMNQTFWIGIYPGLTTE
HHHHHHHHHHHCEEEEEECHHHCCCCCCCEEEEEEECCCCHHHHHCCEEEEEECCCCCHH
HLDYVVSKFEEFFGLNF
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TANNLREQISQLVAQYANEALSPKPFVAGTSVVPPSGKVIGAKELQLMVEASLDGWLTT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECHHHHEEEEEECCCCCEEC
GRFNDAFEKKLGEFIGVPHVLTTTSGSSANLLALTALTSPKLGERALKPGDEVITVAAGF
CCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCHHHCCCCCCEEEEEECC
PTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSKAIMIAHTLGNAFNLSEVRRI
CCCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
ADKYNLWLIEDCCDALGTTYEGQMVGTFGDIGTVSFYPAHHITMGEGGAVFTKSGELKKI
HHHHCEEEHHHHHHHHCCCCCCEEEECCCCCCCEEEECCEEEEECCCCEEEECCCHHHHH
IESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGYDHKYTYSHLGYNLKITDMQAACGL
HHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEHHHCCEEEEEECHHHHHHH
AQLERVEEFVEQRKANFSYLKQGLQSCTEFLELPEATEKSDPSWFGFPITLKETSGVNRV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCHH
ELVKFLDEAKIGTRLLFAGNLIRQPYFANVKYRVVGELTNTDRIMNQTFWIGIYPGLTTE
HHHHHHHHHHHCEEEEEECHHHCCCCCCCEEEEEEECCCCHHHHHCCEEEEEECCCCCHH
HLDYVVSKFEEFFGLNF
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609