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The map label for this gene is aroD [H]

Identifier: 194734603

GI number: 194734603

Start: 1403586

End: 1404344

Strand: Reverse

Name: aroD [H]

Synonym: SeSA_A1454

Alternate gene names: 194734603

Gene position: 1404344-1403586 (Counterclockwise)

Preceding gene: 194736749

Following gene: 194735103

Centisome position: 29.82

GC content: 51.65

Gene sequence:

>759_bases
ATGAAAACCGTAACTGTAAGAGATCTCGTGGTTGGCGAAGGCGCGCCAAAGATCATTGTGTCGCTAATGGGAAAAACCAT
TACCGATGTGAAATCGGAAGCACTCGCCTACCGTGAAGCGGATTTCGATATTCTGGAGTGGCGCGTTGACCATTTTGCCA
ACGTGACGACGGCAGAAAGCGTACTTGAGGCCGCCGGCGCCATCCGGGAGATTATTACCGATAAACCCTTGCTATTTACC
TTCCGCAGCGCGAAAGAAGGCGGCGAACAGGCGCTAACCACCGGACAGTATATCGCTCTGAATCGTGCAGCGGTTGACAG
CGGTCTGGTCGATATGATCGATCTTGAGCTTTTTACCGGCGACGATGAGGTGAAAGCCACCGTCGGCTATGCTCATCAAC
ACAATGTTGCGGTGATCATGTCTAACCATGATTTTCATAAAACGCCCGCAGCGGAAGAGATTGTTCAGCGTCTGCGTAAA
ATGCAGGAACTGGGCGCCGATATTCCGAAGATCGCCGTCATGCCACAGACTAAAGCCGATGTCCTGACCTTACTTACCGC
CACTGTAGAAATGCAGGAGCGCTATGCGGATCGTCCGATTATTACCATGTCGATGTCGAAAACCGGGGTAATATCTCGTC
TTGCCGGCGAAGTGTTCGGTTCTGCAGCAACGTTTGGCGCGGTGAAAAAAGCATCTGCGCCGGGACAAATATCGGTAGCC
GATCTGCGTACCGTATTAACTATATTGCACCAGGCGTAA

Upstream 100 bases:

>100_bases
CAGGAAAAGCATTTCCATTGGACTATGTGAAGCAGGTGATGGGATTCACAGCCTGACCGGTAAAATTATAATTGCGACGA
ATGACAATGAAGGGTACCAA

Downstream 100 bases:

>100_bases
TACTTTATCGTGTGGCGGAATATTCTCTTTCTGCCACAATAAAATAAATAGTTATCTGATATGAATATGTTACATATTCA
TTGAAAGCCGCTGTCTTTAT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAESVLEAAGAIREIITDKPLLFT
FRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRK
MQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVA
DLRTVLTILHQA

Sequences:

>Translated_252_residues
MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAESVLEAAGAIREIITDKPLLFT
FRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRK
MQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVA
DLRTVLTILHQA
>Mature_252_residues
MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAESVLEAAGAIREIITDKPLLFT
FRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRK
MQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVA
DLRTVLTILHQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=252, Percent_Identity=80.5555555555556, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 27282; Mature: 27282

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAES
CCCEEEEHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHH
VLEAAGAIREIITDKPLLFTFRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTG
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCEEEEEHHHHCCCCCEEEEEEEECC
DDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRKMQELGADIPKIAVMPQTKAD
CCHHEEEECEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
VLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVA
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEHH
DLRTVLTILHQA
HHHHHHHHHHCC
>Mature Secondary Structure
MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAES
CCCEEEEHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHH
VLEAAGAIREIITDKPLLFTFRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTG
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCEEEEEHHHHCCCCCEEEEEEEECC
DDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRKMQELGADIPKIAVMPQTKAD
CCHHEEEECEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
VLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVA
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEHH
DLRTVLTILHQA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA