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The map label for this gene is clpP [H]

Identifier: 194734371

GI number: 194734371

Start: 4335277

End: 4336125

Strand: Direct

Name: clpP [H]

Synonym: SeSA_A4464

Alternate gene names: 194734371

Gene position: 4335277-4336125 (Clockwise)

Preceding gene: 194734728

Following gene: 194735635

Centisome position: 92.06

GC content: 56.18

Gene sequence:

>849_bases
ATGAGCAAAAAACAACTTCCGGTAGCACCGGCGGGGCGCCCCTGTGCGCGCGTTACCTGTGAAACCCTTCCTTCCGCACT
GGACCGCTGGAACGGCGGGATCAAAGCTGCGGCCACTGACGACAACAGTATTTCTGTTTTTGATGTGATCGGGCAGGACT
ACTGGGGTGAAGGCGTAACAGCCAAACGTATCGCCGGTGCGCTACGGGCGATGAATGGCGCCGACGTCACGGTCAATATC
AACTCCCCTGGCGGTGACATGTTCGAAGGCCTGGCCATCTACAACCTGCTGCGTGAATACCAGGGGAAAGTTACGGTCAA
GGTGCTGGGCATTGCCGCCAGCGCCGCCTCTGTTATCGCGATGGCCGGGGATGATATTCAGATTGGTCGTGGGGCCTTCC
TGATGATCCACAACTGCTGGGTGGTGGCAATGGGTAACCGGCATGACTTTGCTGAATTATCTGCCTCTCTCGAACCGTTT
GATAACGCAATGGCTGACATTTACGCCGCACGCTCCGGGCTTGATATGGTCACAGTGCAAAAACTGATGGATGCCGAAAG
CTACATCGGCGGTAGCGATGCCGTGGAGAAAGGTCTGGCCGACAGCCTTCTTTCTGCTGATGCCGTAAGTGACGGTGACG
AAACTCCTGCTGCAGCGTTGCGTAAGCTCGATGCGTTGCTGGCAAAGACCAGCACTCCGCGATCTGAACGCCGGAAACTG
ATTAAAGCCCTGTCCGGTGGCATGTCTGGCGCTGCCACCAACCATGACGGCACGCCGGGCGCTGCCGAAGAAATAAAACC
TGAAGTCATCAATTCTCTTGAAAACGCCCTCGCTGCGTTAGTCAAATAA

Upstream 100 bases:

>100_bases
GTTCAGGCTCTGGCCCTGAGAGAACTGCATAACCACGTATTCCCCGATATTTCCTTTGAACAATCTCCGCTGAAACAGGC
CGCTTAGGAGCACTTTCCTG

Downstream 100 bases:

>100_bases
GGACCTTTTATGTCTGAAGTAAATGAAATTCTGAAAAAAGTTACCGCCAGCATTGAAGAGGCGACGGATAAGTTTAATGC
CAGGGCTGAAGATGCACTTA

Product: ClpP protease

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSKKQLPVAPAGRPCARVTCETLPSALDRWNGGIKAAATDDNSISVFDVIGQDYWGEGVTAKRIAGALRAMNGADVTVNI
NSPGGDMFEGLAIYNLLREYQGKVTVKVLGIAASAASVIAMAGDDIQIGRGAFLMIHNCWVVAMGNRHDFAELSASLEPF
DNAMADIYAARSGLDMVTVQKLMDAESYIGGSDAVEKGLADSLLSADAVSDGDETPAAALRKLDALLAKTSTPRSERRKL
IKALSGGMSGAATNHDGTPGAAEEIKPEVINSLENALAALVK

Sequences:

>Translated_282_residues
MSKKQLPVAPAGRPCARVTCETLPSALDRWNGGIKAAATDDNSISVFDVIGQDYWGEGVTAKRIAGALRAMNGADVTVNI
NSPGGDMFEGLAIYNLLREYQGKVTVKVLGIAASAASVIAMAGDDIQIGRGAFLMIHNCWVVAMGNRHDFAELSASLEPF
DNAMADIYAARSGLDMVTVQKLMDAESYIGGSDAVEKGLADSLLSADAVSDGDETPAAALRKLDALLAKTSTPRSERRKL
IKALSGGMSGAATNHDGTPGAAEEIKPEVINSLENALAALVK
>Mature_281_residues
SKKQLPVAPAGRPCARVTCETLPSALDRWNGGIKAAATDDNSISVFDVIGQDYWGEGVTAKRIAGALRAMNGADVTVNIN
SPGGDMFEGLAIYNLLREYQGKVTVKVLGIAASAASVIAMAGDDIQIGRGAFLMIHNCWVVAMGNRHDFAELSASLEPFD
NAMADIYAARSGLDMVTVQKLMDAESYIGGSDAVEKGLADSLLSADAVSDGDETPAAALRKLDALLAKTSTPRSERRKLI
KALSGGMSGAATNHDGTPGAAEEIKPEVINSLENALAALVK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 29409; Mature: 29277

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKQLPVAPAGRPCARVTCETLPSALDRWNGGIKAAATDDNSISVFDVIGQDYWGEGVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCHHCCCCCH
AKRIAGALRAMNGADVTVNINSPGGDMFEGLAIYNLLREYQGKVTVKVLGIAASAASVIA
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHEEE
MAGDDIQIGRGAFLMIHNCWVVAMGNRHDFAELSASLEPFDNAMADIYAARSGLDMVTVQ
ECCCCEEECCCEEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
KLMDAESYIGGSDAVEKGLADSLLSADAVSDGDETPAAALRKLDALLAKTSTPRSERRKL
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IKALSGGMSGAATNHDGTPGAAEEIKPEVINSLENALAALVK
HHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKKQLPVAPAGRPCARVTCETLPSALDRWNGGIKAAATDDNSISVFDVIGQDYWGEGVT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCHHCCCCCH
AKRIAGALRAMNGADVTVNINSPGGDMFEGLAIYNLLREYQGKVTVKVLGIAASAASVIA
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHEEE
MAGDDIQIGRGAFLMIHNCWVVAMGNRHDFAELSASLEPFDNAMADIYAARSGLDMVTVQ
ECCCCEEECCCEEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
KLMDAESYIGGSDAVEKGLADSLLSADAVSDGDETPAAALRKLDALLAKTSTPRSERRKL
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IKALSGGMSGAATNHDGTPGAAEEIKPEVINSLENALAALVK
HHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA