Click here to switch to the map view.

The map label for this gene is tmcA [H]

Identifier: 194734085

GI number: 194734085

Start: 2598757

End: 2600775

Strand: Reverse

Name: tmcA [H]

Synonym: SeSA_A2718

Alternate gene names: 194734085

Gene position: 2600775-2598757 (Counterclockwise)

Preceding gene: 194738170

Following gene: 194737239

Centisome position: 55.23

GC content: 63.0

Gene sequence:

>2019_bases
ATGTCTGATATCGATGCGCTACAGGCGTTAACGTCGCAAATGACACAGGAAGGCATTCGCCGTTTACTGGTCATCAGCGG
CGATGCGGCGTGGTGCCGGGAGCGGGCCGAGGCGATACGCGCTGCGCTGCCCGGTGACTGGCTGTGGGTTGCGCCTGACG
CGCCCGCGCAGCCGCGCTGTACGCCACAGGCGTTACAAACGCTGCTGGGCCGTGAATTTCGTCATGCGATATTTGATGCC
TGGCAGGGCTTTGACGCCGCAGCGTTTGCCGCCCTGAGCGGGACCTTGCAGGCCGGAAGCTGGCTGCTTCTGCTGATGCC
GCCGTATGAGACGTGGGAAAGCAGGCCTGATACCGATTCACTGCGCTGGAGCGACTGCGCGCAGCCTATCCCCACACCGC
AGTTTGCACAGCATCTTAAACGGACTCTCTCCCGCGATCCGCAAACGCTGCTTTGGCGACAGCGCCAGCCGTTTTGCTGG
CCATCTTATCCTTCCCGTGAACGCTGGCGACCCGCCACCGGCGAGCCGCAGCCGGAGCAGGCGGCTATCTTATCGCGTTT
ACGTGAAATGCCGCCCGGCGTGGCGACGGTGATTGCCCCCCGTGGGCGCGGCAAATCGGCGCTGGCCGGGCAATTCATCT
CCCGGATGGCGGGCACGGCTATCGTGACCGCACCGGCGAAAACGGCAACGGATATCCTGGCAGCGTTTGCCGGTGAGCGG
TTCTGCTTTATGGCGCCGGATGCGTTGCTGGCGAGCGGGGCAAGAGCCGACTGGCTGGTAGTTGACGAGGCGGCGGCAAT
CCCCTCGCCGCTGCTGCTGCAACTGGTTTCGCGCTTTCCCCGCATACTACTCACCACCACCGTTCAGGGCTACGAAGGCA
CCGGACGCGGTTTTTTACTTAAGTTTTGCGCCCGTTTTCCGCAGCTTCACCGCTTCACGCTTCGTCAGCCTGTCCGCTGG
GCGCCAGAATGCCCGCTGGAAAATATCGTCAGCGAGGCGCTGATATTCGACGATGAAGCGTTTGCGCAGGCGCCACATGG
CGCGATAGCAATCTCGGCGTTTTACCAACAGGCCTGGGGGGAGACGCCCGCGTTGCCGAGGGCTGTGTATCAGTTACTGT
CGGGGGCGCACTATCGTACTTCGCCGCTGGATCTGCGCCGAATGATGGATGCGCCAGGGCAGCATTTTTTGCAGGCTACG
GCGAATAACCGTGTGGCGGGCGCCCTCTGGCTGGTCGAAGAGGGCGGGCTATCCGCAGAACTCAGTCAGGCTGTATGGGC
CGGTTTCCGGCGTCCGCGTGGAAATCTGGTGGCGCAGTCGCTGGCGGCGCACGGTAGCGACCCTTTAGCCGCCACGCTGG
TCGGGCGTCGCGTAAGCCGTATCGCGGTGCACCCCGCCCGCCAGCGCGAAGGCATCGGTCAGCAGTTGATTGCCTGCGCG
TGCATGCAGGCGGCGCAGTGTGATTATCTTTCCGTCAGCTTCGGCTATACGCCGGAGCTGTGGCGTTTCTGGCAACGCTG
CGGCTTTGTACTGGTACGGATGGGCAACCATCGGGAGGCGAGCAGCGGTTGCTATACGGCGATGGCGTTATTGCCGCTGA
GCGACGCGGGAAAACGGCTGGCGCAGCAGGAACACCGACGTTTGCGCCGCGATGCGGATATCCTGACGCAGTGGAACGGC
GAGGCGATACCGCTGGCGGCGTTAGATGAACAGGCGCTTAATGATGAAGACTGGCGTGAGCTGGTCGGTTTTGCGTTCGC
GCACCGCCCGCTACTGACATCGTTAGGTTGCCTGCATCGTTTACTGCAATACAGCGCATTGCCATTACCGGCGCTGAGAG
GGCGGCTGGAAGAAAAAGCCAGCGATGCCGAACTGTGCGCCCGGCTACGCATTTCAGGCCGTAAAGCTCTGCTGGCGTTG
CAGCGTGTGCAGACGGCGCAGGCGCTGATTGCGCTGGATGCCGGACGAACGCAGCGTTTGCGCGACGTAATGCCCGGCGG
TGGGGACCATGCCGGATAG

Upstream 100 bases:

>100_bases
CTCAGAACAGCGCTACAGCTGGTTTAAGCGTGGATTTGACAGCGGTGACCCGGCGCAATGTAATACGTTTGGCAAAAACT
TTTGATAAACCGGGGCAGGG

Downstream 100 bases:

>100_bases
CGATACCTGTCCGGCATGTTATCCGGTTACTTTTTCGGCTGATCTTTCTTCGGCCAGTCTTCTTCATCGTCCCACTTATC
GTTAAAATCGCGATGCGGGG

Product: acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSDIDALQALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAALPGDWLWVAPDAPAQPRCTPQALQTLLGREFRHAIFDA
WQGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCW
PSYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISRMAGTAIVTAPAKTATDILAAFAGER
FCFMAPDALLASGARADWLVVDEAAAIPSPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRW
APECPLENIVSEALIFDDEAFAQAPHGAIAISAFYQQAWGETPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQAT
ANNRVAGALWLVEEGGLSAELSQAVWAGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACA
CMQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPLSDAGKRLAQQEHRRLRRDADILTQWNG
EAIPLAALDEQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLAL
QRVQTAQALIALDAGRTQRLRDVMPGGGDHAG

Sequences:

>Translated_672_residues
MSDIDALQALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAALPGDWLWVAPDAPAQPRCTPQALQTLLGREFRHAIFDA
WQGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCW
PSYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISRMAGTAIVTAPAKTATDILAAFAGER
FCFMAPDALLASGARADWLVVDEAAAIPSPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRW
APECPLENIVSEALIFDDEAFAQAPHGAIAISAFYQQAWGETPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQAT
ANNRVAGALWLVEEGGLSAELSQAVWAGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACA
CMQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPLSDAGKRLAQQEHRRLRRDADILTQWNG
EAIPLAALDEQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLAL
QRVQTAQALIALDAGRTQRLRDVMPGGGDHAG
>Mature_671_residues
SDIDALQALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAALPGDWLWVAPDAPAQPRCTPQALQTLLGREFRHAIFDAW
QGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWP
SYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISRMAGTAIVTAPAKTATDILAAFAGERF
CFMAPDALLASGARADWLVVDEAAAIPSPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRWA
PECPLENIVSEALIFDDEAFAQAPHGAIAISAFYQQAWGETPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATA
NNRVAGALWLVEEGGLSAELSQAVWAGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACAC
MQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPLSDAGKRLAQQEHRRLRRDADILTQWNGE
AIPLAALDEQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQ
RVQTAQALIALDAGRTQRLRDVMPGGGDHAG

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=662, Percent_Identity=72.2054380664652, Blast_Score=969, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640662, Length=244, Percent_Identity=27.0491803278689, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 74080; Mature: 73949

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIDALQALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAALPGDWLWVAPDAPAQPRC
CCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
TPQALQTLLGREFRHAIFDAWQGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDS
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCC
LRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWPSYPSRERWRPATGEPQPEQ
CCHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAILSRLREMPPGVATVIAPRGRGKSALAGQFISRMAGTAIVTAPAKTATDILAAFAGER
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCC
FCFMAPDALLASGARADWLVVDEAAAIPSPLLLQLVSRFPRILLTTTVQGYEGTGRGFLL
EEEECCHHHHHCCCCCCEEEEECHHHCCCHHHHHHHHHCCCEEEHEEECCCCCCCCHHHH
KFCARFPQLHRFTLRQPVRWAPECPLENIVSEALIFDDEAFAQAPHGAIAISAFYQQAWG
HHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCC
ETPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATANNRVAGALWLVEEGGLSAE
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCHH
LSQAVWAGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACA
HHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHH
CMQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPLSDAGKRL
HHHHHCCCEEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHH
AQQEHRRLRRDADILTQWNGEAIPLAALDEQALNDEDWRELVGFAFAHRPLLTSLGCLHR
HHHHHHHHHHHHHHHHCCCCCEEEHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQRVQTAQALIALDAGRTQRL
HHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
RDVMPGGGDHAG
HHHCCCCCCCCC
>Mature Secondary Structure 
SDIDALQALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAALPGDWLWVAPDAPAQPRC
CHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
TPQALQTLLGREFRHAIFDAWQGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDS
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCC
LRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWPSYPSRERWRPATGEPQPEQ
CCHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAILSRLREMPPGVATVIAPRGRGKSALAGQFISRMAGTAIVTAPAKTATDILAAFAGER
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCC
FCFMAPDALLASGARADWLVVDEAAAIPSPLLLQLVSRFPRILLTTTVQGYEGTGRGFLL
EEEECCHHHHHCCCCCCEEEEECHHHCCCHHHHHHHHHCCCEEEHEEECCCCCCCCHHHH
KFCARFPQLHRFTLRQPVRWAPECPLENIVSEALIFDDEAFAQAPHGAIAISAFYQQAWG
HHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCC
ETPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATANNRVAGALWLVEEGGLSAE
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCHH
LSQAVWAGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACA
HHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHH
CMQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPLSDAGKRL
HHHHHCCCEEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHH
AQQEHRRLRRDADILTQWNGEAIPLAALDEQALNDEDWRELVGFAFAHRPLLTSLGCLHR
HHHHHHHHHHHHHHHHCCCCCEEEHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQRVQTAQALIALDAGRTQRL
HHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
RDVMPGGGDHAG
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]