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The map label for this gene is aegA [H]

Identifier: 194737239

GI number: 194737239

Start: 2589296

End: 2591257

Strand: Reverse

Name: aegA [H]

Synonym: SeSA_A2712

Alternate gene names: 194737239

Gene position: 2591257-2589296 (Counterclockwise)

Preceding gene: 194734085

Following gene: 194734362

Centisome position: 55.03

GC content: 58.56

Gene sequence:

>1962_bases
ATGAATCGTTTTATTATGGCCAATAGCCAGCAGTGTCTGGGCTGCCATGCCTGCGAGGTCGCCTGCGTAATGGCTCACAA
TGATGAGCGACATGTCCTGACGTCACAGCGCTATCAGCCCCGAATTACTGTCATCAAACATCAGCACCAGCGCAGCGCGG
TCACATGTCACCATTGCGAAGATGCGCCCTGCGCCCGTAGCTGTCCGAACGGCGCGATCGCGCATATTAACAACAGCGTG
CAGGTCAATGCGCAGAAGTGCATCGGCTGTAAATCCTGCGTCGTCGCCTGCCCATTCGGCACCATGCAGATGGTATTGAC
GCCCGTCGCGCCAAACCAGTTCAAAGCCAGCGCGCATAAATGCGATCTGTGTCAGGGACGTGAACAGGGTCCGGCCTGCG
TGGAAAATTGCCCGGCGGATGCGCTGCAACTGGTCACCGAAGACTCGTTGACCCGTCTGGCTAAAACGCGACGGCTGCGT
ACCGCCCGGCAGGAGATTCGCCCCTGGCATACCGTGGATACACAACACAGTGGGACAGCAAGCAGCAAAGTCGAGCGTAT
GCAGGCGACGCCGCCACGCGGCGAACCGGATAAACTGGCGATTGAAGCGCGTAAAACCACCTTTGAGGAAATTTATCTGC
CGTTTCGCGCCGCGCAGGCCGAGCGTGAAGCGTCCCGCTGCCTCACATGCGGGGAACACAGTATCTGCGAATGGACCTGT
CCTCTGCATAACCATATTCCCCAGTGGATCGAACTGGTGAAAGCCGGCGATATTGATGCGGCGGTAGAGCTTTCCCACCA
GACCAACTGCCTGCCGGAAATTACCGGGCGCGTCTGTCCGCAGGACCGGCTATGCGAAGGCGCGTGTACACTCCGCGATG
AGTATGGCGCGGTTACCATCGGCAACATTGAGCGCTATATCTCCGATCGCGCTCTGAGCAAAGGCTGGCGTCCCGACCTG
TCGGACGTACAGAAGAGCGATAAGCGCGTGGCGATTATCGGCGCGGGGCCGGCAGGTCTTGCCTGCGCTGACGTGCTGGC
GCGCCATGGCGTAAGCGCCACCGTCTACGATCGCCACCCGGAAATCGGCGGTTTGCTCACCTTTGGTATTCCGGCTTTCA
AACTGGATAAATCTCTGCTGGCGCGCCGTCGGGAAATCTTCAGCGCGATGGGGATTCGTTTCGAGCTTAACTGCGAAGTA
GGGAAAGATATTTCTCTGGAGACGCTGCTGGAGAGTTATGACGCCGTCTTTGTCGGGGTAGGAACCTACCGTTCCATGAA
GGCTGATTTACCGAATGAAGACGCGCCGGGGGTATATGATGCGTTGCCATTCCTCATCGCCAATACCAAACAGGTGATGG
GGCTTCCGGCGTTGCCTGACGAGCCGTTTATTGATACTGCGGGCCTTAACGTGGTTGTGCTGGGCGGCGGTGACACCGCA
ATGGACTGCGTACGTACGGCGCTGCGTCATGGCGCTGCCAACGTCACCTGCGCTTATCGCCGTGATGAGGCCAATATGCC
GGGGTCGAAAAAAGAGGTGAAAAACGCGCGGGAAGAGGGCGCGAACTTTGAATTTAACGTTCAGCCGGTTGAGTTGGTGC
TGGATACGCACGGGCGCGTCAGCGGTATTCGCTTTTTGCGTACGCGGCTTGGCGAACCGGATGGTCAGGGGCGACGCCGT
CCGGTACCTGTACCGGACAGCGAGTTCGTGATGCCGGCGGATGCGGTCATTATGGCGTTTGGTTTTCATCCGCATGGTAT
GTCGTGGCTGGAATCGCATGGCGTGAAGGTGGATAACTGGGGACGTATTGCCGCCAGCGTCGAGAGCGAGTTTCGTTACC
AGACGTCCAACCCGAAAATTTTCGCCGGCGGCGATGCGGTGCGCGGCGCCGATCTGGTGGTGACGGCGATGGCAGAAGGC
CGACATGCCGCGCAGGGGATACTCGACTGGTTAGCTAAATAA

Upstream 100 bases:

>100_bases
TGCTTCCTGGGCAGATGAACATTGCCGACCCCGCCTTCGTCAGTTAATAACAATGCTCATATAAAGAATAAGGTTTTTAC
AACCAAAACAGAAGGATGCC

Downstream 100 bases:

>100_bases
GCGTATTTGTAGGCCGGTTAAGGCCTGGAACGGTTAAATGATTGAGTGATAAAAAATCTTAAACTTATTGGCTAACCTTA
CTCCGTTTGCAGAAATGTTG

Product: putative oxidoreductase Fe-S binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTSQRYQPRITVIKHQHQRSAVTCHHCEDAPCARSCPNGAIAHINNSV
QVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
TARQEIRPWHTVDTQHSGTASSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREASRCLTCGEHSICEWTC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDL
SDVQKSDKRVAIIGAGPAGLACADVLARHGVSATVYDRHPEIGGLLTFGIPAFKLDKSLLARRREIFSAMGIRFELNCEV
GKDISLETLLESYDAVFVGVGTYRSMKADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTA
MDCVRTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRVSGIRFLRTRLGEPDGQGRRR
PVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEG
RHAAQGILDWLAK

Sequences:

>Translated_653_residues
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTSQRYQPRITVIKHQHQRSAVTCHHCEDAPCARSCPNGAIAHINNSV
QVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
TARQEIRPWHTVDTQHSGTASSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREASRCLTCGEHSICEWTC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDL
SDVQKSDKRVAIIGAGPAGLACADVLARHGVSATVYDRHPEIGGLLTFGIPAFKLDKSLLARRREIFSAMGIRFELNCEV
GKDISLETLLESYDAVFVGVGTYRSMKADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTA
MDCVRTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRVSGIRFLRTRLGEPDGQGRRR
PVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEG
RHAAQGILDWLAK
>Mature_653_residues
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTSQRYQPRITVIKHQHQRSAVTCHHCEDAPCARSCPNGAIAHINNSV
QVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
TARQEIRPWHTVDTQHSGTASSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREASRCLTCGEHSICEWTC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDL
SDVQKSDKRVAIIGAGPAGLACADVLARHGVSATVYDRHPEIGGLLTFGIPAFKLDKSLLARRREIFSAMGIRFELNCEV
GKDISLETLLESYDAVFVGVGTYRSMKADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTA
MDCVRTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRVSGIRFLRTRLGEPDGQGRRR
PVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEG
RHAAQGILDWLAK

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=503, Percent_Identity=29.2246520874751, Blast_Score=167, Evalue=4e-41,
Organism=Escherichia coli, GI1788811, Length=652, Percent_Identity=85.1226993865031, Blast_Score=1170, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=649, Percent_Identity=54.6995377503852, Blast_Score=723, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=459, Percent_Identity=65.5773420479303, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1788468, Length=459, Percent_Identity=30.2832244008715, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1789067, Length=172, Percent_Identity=48.8372093023256, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1789243, Length=420, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI87082179, Length=157, Percent_Identity=45.859872611465, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI2367245, Length=154, Percent_Identity=48.0519480519481, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1789079, Length=207, Percent_Identity=36.7149758454106, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI87082114, Length=188, Percent_Identity=36.1702127659575, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1787122, Length=161, Percent_Identity=31.6770186335404, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790326, Length=168, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787749, Length=174, Percent_Identity=28.1609195402299, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI2367345, Length=155, Percent_Identity=33.5483870967742, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787872, Length=153, Percent_Identity=31.3725490196078, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789370, Length=201, Percent_Identity=28.3582089552239, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI226510944, Length=100, Percent_Identity=40, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17570289, Length=476, Percent_Identity=33.1932773109244, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI71984108, Length=447, Percent_Identity=31.5436241610738, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17543860, Length=162, Percent_Identity=32.0987654320988, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320030, Length=471, Percent_Identity=33.9702760084926, Blast_Score=223, Evalue=5e-59,
Organism=Drosophila melanogaster, GI28574881, Length=468, Percent_Identity=36.3247863247863, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI24665539, Length=468, Percent_Identity=36.3247863247863, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI24665547, Length=468, Percent_Identity=36.3247863247863, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24665543, Length=468, Percent_Identity=36.3247863247863, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24640763, Length=461, Percent_Identity=29.7180043383948, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI18858217, Length=461, Percent_Identity=29.7180043383948, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 71504; Mature: 71504

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTSQRYQPRITVIKHQHQRSAVTCHHCE
CCCEEECCCCCCCCCHHHEEEEEEECCCCCCEECCCCCCCEEEEEEECCCCCCEEEECCC
DAPCARSCPNGAIAHINNSVQVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHK
CCCHHHCCCCCCEEEECCCEEECHHHHCCCCHHEEECCCCCEEEEEECCCCCCCCCCCCC
CDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLRTARQEIRPWHTVDTQHSGTA
CHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
SSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREASRCLTCGEHSICEWTC
HHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTI
CHHHCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCHHHHCCCHHEEECCCCEEEE
GNIERYISDRALSKGWRPDLSDVQKSDKRVAIIGAGPAGLACADVLARHGVSATVYDRHP
CCHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCC
EIGGLLTFGIPAFKLDKSLLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGV
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCEEEEEC
GTYRSMKADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTA
CCCHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCEECCCCEEEEECCCCHH
MDCVRTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRV
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCEEEEEEECCCCH
SGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNW
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCHHHHHCCCEECCC
GRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK
CHHHHHHHHHHEEECCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTSQRYQPRITVIKHQHQRSAVTCHHCE
CCCEEECCCCCCCCCHHHEEEEEEECCCCCCEECCCCCCCEEEEEEECCCCCCEEEECCC
DAPCARSCPNGAIAHINNSVQVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHK
CCCHHHCCCCCCEEEECCCEEECHHHHCCCCHHEEECCCCCEEEEEECCCCCCCCCCCCC
CDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLRTARQEIRPWHTVDTQHSGTA
CHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
SSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREASRCLTCGEHSICEWTC
HHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTI
CHHHCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCHHHHCCCHHEEECCCCEEEE
GNIERYISDRALSKGWRPDLSDVQKSDKRVAIIGAGPAGLACADVLARHGVSATVYDRHP
CCHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCC
EIGGLLTFGIPAFKLDKSLLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGV
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCEEEEEC
GTYRSMKADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTA
CCCHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCEECCCCEEEEECCCCHH
MDCVRTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRV
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCEEEEEEECCCCH
SGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNW
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCHHHHHCCCEECCC
GRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK
CHHHHHHHHHHEEECCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]