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The map label for this gene is mraY

Identifier: 194335054

GI number: 194335054

Start: 2444635

End: 2445741

Strand: Reverse

Name: mraY

Synonym: Paes_2266

Alternate gene names: 194335054

Gene position: 2445741-2444635 (Counterclockwise)

Preceding gene: 194335055

Following gene: 194335053

Centisome position: 97.33

GC content: 51.04

Gene sequence:

>1107_bases
ATGCTCTATTACCTGTTACAGTATATCAACGACGTTTTTGATCCACCGGGTTTCGGTGTTGTCGAATATATCACCTTCAG
GGCCAGCGCGGCCGCTATTACCTCCCTGCTTATCACGATCTTTGTCGGTCCGAGGCTGATCGCCTACCTGAAGAGAAAAT
ATATTGAACCGATCAAGGAGGAGGCTCCCCCGGAACATCGCAAGAAGAAAGAGCTTCCTACGATGGGAGGGACGCTGATT
ATTTTTTCCATTCTTGTTTCAGGGCTGCTCTGGTCGCGTTTCAATGACCCGTATGTCTGGCTTATTCTTCTGGCTATTCT
CTGGATGGGGACTATCGGTTTTATTGACGACTACCGCAAGGTGGTTCTGAAAATCAAAGGGGGGCTTGCTGCCCGCTACA
AACTGATCGGGCAGGTGTCGCTTGGCCTGGTGGTTGGTCTCTATACCTGGTATGACCCGGCTTTTTCAGTACTTCAGTCG
CAGACGACGGTTCCTTTTTTTAAGAATCTGACGATCAACTACGGGATTTTCTATATCCCTCTGGTCGTGTTTATTATCAC
AGCGGTATCCAACGCGGTCAACCTGACCGACGGACTTGACGGCCTGGCTTCCGGAGTTTCGGGTATCGTGGTCTTTGCCC
TTGGCGGATTTGCCTATCTTACAGGCAATACGGTGTATGCCGACTACCTCAATATCAATTACATTTCCGGTGCCGGCGAG
GTGGCGATCCTCAGCATGGCGATTGCAATGTCGTGCGTCGGATTTCTCTGGTTCAATTCGCACCCTGCAGAGATTATCAT
GGGCGATACGGGATCGCTTGCTCTCGGAAGTGCTATCGCGGTCATCGCTCTTCTTATCAAGCAGGAGCTGCTTCTGCCCG
TGCTTGCCGGAACCTTTCTTCTCGAAACTCTTTCGGTTTCGCTCCAGGTGGCATGGTTCAAGTTCACCCGCTGGCGTTTC
GGAGAGGGGCGCAGGATTTTCCTGATGGCGCCGCTGCACCATCATTTTCAGCTCAAAGGATGGGCTGAGGAGAAAATCGT
CATTCGTTTCTGGATCATCACCCTGTTGTTTTTTCTCACCAGTCTTATGACGCTGAAACTGCGCTGA

Upstream 100 bases:

>100_bases
CCTTCTTAAAGGGTCGAGAGGGATGAGGCTCGAACTGATAGCTGAAGGCCTTCGAGCCACCGACAAGTAGAAAGAATTAT
TTTTTCAGAAAATCTCTATC

Downstream 100 bases:

>100_bases
TGCATACTGCTCCGCTACAGATCGAGGGTGCCAGGGTAAGCGTCATCGGCGCCCGGCGCAGCGGCATCGCAGCTGCTCTG
CTCATGCGTGAACAGGGTGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MLYYLLQYINDVFDPPGFGVVEYITFRASAAAITSLLITIFVGPRLIAYLKRKYIEPIKEEAPPEHRKKKELPTMGGTLI
IFSILVSGLLWSRFNDPYVWLILLAILWMGTIGFIDDYRKVVLKIKGGLAARYKLIGQVSLGLVVGLYTWYDPAFSVLQS
QTTVPFFKNLTINYGIFYIPLVVFIITAVSNAVNLTDGLDGLASGVSGIVVFALGGFAYLTGNTVYADYLNINYISGAGE
VAILSMAIAMSCVGFLWFNSHPAEIIMGDTGSLALGSAIAVIALLIKQELLLPVLAGTFLLETLSVSLQVAWFKFTRWRF
GEGRRIFLMAPLHHHFQLKGWAEEKIVIRFWIITLLFFLTSLMTLKLR

Sequences:

>Translated_368_residues
MLYYLLQYINDVFDPPGFGVVEYITFRASAAAITSLLITIFVGPRLIAYLKRKYIEPIKEEAPPEHRKKKELPTMGGTLI
IFSILVSGLLWSRFNDPYVWLILLAILWMGTIGFIDDYRKVVLKIKGGLAARYKLIGQVSLGLVVGLYTWYDPAFSVLQS
QTTVPFFKNLTINYGIFYIPLVVFIITAVSNAVNLTDGLDGLASGVSGIVVFALGGFAYLTGNTVYADYLNINYISGAGE
VAILSMAIAMSCVGFLWFNSHPAEIIMGDTGSLALGSAIAVIALLIKQELLLPVLAGTFLLETLSVSLQVAWFKFTRWRF
GEGRRIFLMAPLHHHFQLKGWAEEKIVIRFWIITLLFFLTSLMTLKLR
>Mature_368_residues
MLYYLLQYINDVFDPPGFGVVEYITFRASAAAITSLLITIFVGPRLIAYLKRKYIEPIKEEAPPEHRKKKELPTMGGTLI
IFSILVSGLLWSRFNDPYVWLILLAILWMGTIGFIDDYRKVVLKIKGGLAARYKLIGQVSLGLVVGLYTWYDPAFSVLQS
QTTVPFFKNLTINYGIFYIPLVVFIITAVSNAVNLTDGLDGLASGVSGIVVFALGGFAYLTGNTVYADYLNINYISGAGE
VAILSMAIAMSCVGFLWFNSHPAEIIMGDTGSLALGSAIAVIALLIKQELLLPVLAGTFLLETLSVSLQVAWFKFTRWRF
GEGRRIFLMAPLHHHFQLKGWAEEKIVIRFWIITLLFFLTSLMTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=374, Percent_Identity=45.4545454545455, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PROA2 (B4S6R2)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016914.1
- GeneID:   6459566
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2266
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 41062; Mature: 41062

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f3443a4)-; HASH(0x1f4ed738)-; HASH(0x1f4e817c)-; HASH(0x1f078b98)-; HASH(0x1d5fe4c4)-; HASH(0x1e6c9c78)-; HASH(0x1f479aa0)-; HASH(0x1f4d56f4)-; HASH(0x1f484788)-; HASH(0x1f4fce94)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYLLQYINDVFDPPGFGVVEYITFRASAAAITSLLITIFVGPRLIAYLKRKYIEPIKE
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EAPPEHRKKKELPTMGGTLIIFSILVSGLLWSRFNDPYVWLILLAILWMGTIGFIDDYRK
CCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVLKIKGGLAARYKLIGQVSLGLVVGLYTWYDPAFSVLQSQTTVPFFKNLTINYGIFYIP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEECCHHHHHH
LVVFIITAVSNAVNLTDGLDGLASGVSGIVVFALGGFAYLTGNTVYADYLNINYISGAGE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEEEEEEECCCCH
VAILSMAIAMSCVGFLWFNSHPAEIIMGDTGSLALGSAIAVIALLIKQELLLPVLAGTFL
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LETLSVSLQVAWFKFTRWRFGEGRRIFLMAPLHHHFQLKGWAEEKIVIRFWIITLLFFLT
HHHHHHHHEEEEEEEEHEEECCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
SLMTLKLR
HHHHHCCH
>Mature Secondary Structure
MLYYLLQYINDVFDPPGFGVVEYITFRASAAAITSLLITIFVGPRLIAYLKRKYIEPIKE
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EAPPEHRKKKELPTMGGTLIIFSILVSGLLWSRFNDPYVWLILLAILWMGTIGFIDDYRK
CCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVLKIKGGLAARYKLIGQVSLGLVVGLYTWYDPAFSVLQSQTTVPFFKNLTINYGIFYIP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEECCHHHHHH
LVVFIITAVSNAVNLTDGLDGLASGVSGIVVFALGGFAYLTGNTVYADYLNINYISGAGE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEEEEEEECCCCH
VAILSMAIAMSCVGFLWFNSHPAEIIMGDTGSLALGSAIAVIALLIKQELLLPVLAGTFL
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LETLSVSLQVAWFKFTRWRFGEGRRIFLMAPLHHHFQLKGWAEEKIVIRFWIITLLFFLT
HHHHHHHHEEEEEEEEHEEECCCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
SLMTLKLR
HHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA