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The map label for this gene is atpF2

Identifier: 194335033

GI number: 194335033

Start: 2424288

End: 2424815

Strand: Reverse

Name: atpF2

Synonym: Paes_2245

Alternate gene names: 194335033

Gene position: 2424815-2424288 (Counterclockwise)

Preceding gene: 194335034

Following gene: 194335032

Centisome position: 96.49

GC content: 45.64

Gene sequence:

>528_bases
ATGCTTACGTCAGGAATTGTCATCCTCAGCGGAGGTCTGTTAGACCCTAATCCGGGATTGATTTTCTGGACAGCCGTTAC
TTTTGTTATCGTGCTCCTTATTCTTAAAAAGTTTGCATGGGGACCGATACTTGGTGCTCTTGAAGAGCGCGAAAAAGCAA
TCCAGTCGTCAATTGACAGGGCGCATACCGCAAAAGATGAAGCTGAAGCAGCTCTGAGAAAAAACAAGGAACTGCTTACC
AAAGCGGATGCCGAGGCAGAAAAGATTCTGCGCGAAGGTAAAGAATACGGTGAGAAGCTTCGTGCCGATATTGTTGAAAA
GGCTCATTCTGAAGCGACGAAAATGATTTCATCGGCTAAAGAGGAAATTGAGCAGGAAAAACGCCGTGCACTGGACGAAT
TGAGAAACGAGGTTGCTGATCTTGCTGTACAGGGTGCCGAGAAAATTCTTATGGCCAACCTTGATGCCGACAAGCAGAAA
GCTATTGTCAGCAGTATGATCCAGGATCTTTCAAAACATCGTAACTGA

Upstream 100 bases:

>100_bases
CTTGAAGTAAGCGTATACCATCTATATCTAAGAATCCGGTTGCCGAACGGCGAGTTCTGCAACCGGGCTTTATTTAATCG
ATAAAGGAGAAAAGTATTCC

Downstream 100 bases:

>100_bases
AAACGCTCGGGAAATGTCAAGTGCAATAGCTAGCCGGCGCTACGCCGCAGCCTTACTGGATGTCGCTGAAGATAGCGGTG
TGGTTGAACAAGTAGACACT

Product: F0F1 ATP synthase subunit B

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit b 2; ATPase subunit I 2; F-type ATPase subunit b 2; F-ATPase subunit b 2

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MLTSGIVILSGGLLDPNPGLIFWTAVTFVIVLLILKKFAWGPILGALEEREKAIQSSIDRAHTAKDEAEAALRKNKELLT
KADAEAEKILREGKEYGEKLRADIVEKAHSEATKMISSAKEEIEQEKRRALDELRNEVADLAVQGAEKILMANLDADKQK
AIVSSMIQDLSKHRN

Sequences:

>Translated_175_residues
MLTSGIVILSGGLLDPNPGLIFWTAVTFVIVLLILKKFAWGPILGALEEREKAIQSSIDRAHTAKDEAEAALRKNKELLT
KADAEAEKILREGKEYGEKLRADIVEKAHSEATKMISSAKEEIEQEKRRALDELRNEVADLAVQGAEKILMANLDADKQK
AIVSSMIQDLSKHRN
>Mature_175_residues
MLTSGIVILSGGLLDPNPGLIFWTAVTFVIVLLILKKFAWGPILGALEEREKAIQSSIDRAHTAKDEAEAALRKNKELLT
KADAEAEKILREGKEYGEKLRADIVEKAHSEATKMISSAKEEIEQEKRRALDELRNEVADLAVQGAEKILMANLDADKQK
AIVSSMIQDLSKHRN

Specific function: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)

COG id: COG0711

COG function: function code C; F0F1-type ATP synthase, subunit b

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase B chain family

Homologues:

Organism=Escherichia coli, GI1790174, Length=157, Percent_Identity=38.2165605095541, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPF2_PROA2 (B4S6E4)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016893.1
- GeneID:   6459631
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_2245
- HOGENOM:   HBG617328
- OMA:   NPGLIFW
- ProtClustDB:   PRK14472
- HAMAP:   MF_01398
- InterPro:   IPR002146
- InterPro:   IPR005864
- TIGRFAMs:   TIGR01144

Pfam domain/function: PF00430 ATP-synt_B

EC number: 3.6.3.14

Molecular weight: Translated: 19373; Mature: 19373

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f319464)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSGIVILSGGLLDPNPGLIFWTAVTFVIVLLILKKFAWGPILGALEEREKAIQSSIDR
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHTAKDEAEAALRKNKELLTKADAEAEKILREGKEYGEKLRADIVEKAHSEATKMISSAK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEIEQEKRRALDELRNEVADLAVQGAEKILMANLDADKQKAIVSSMIQDLSKHRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLTSGIVILSGGLLDPNPGLIFWTAVTFVIVLLILKKFAWGPILGALEEREKAIQSSIDR
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHTAKDEAEAALRKNKELLTKADAEAEKILREGKEYGEKLRADIVEKAHSEATKMISSAK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEIEQEKRRALDELRNEVADLAVQGAEKILMANLDADKQKAIVSSMIQDLSKHRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA