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The map label for this gene is bioC [H]

Identifier: 194334976

GI number: 194334976

Start: 2360072

End: 2360878

Strand: Reverse

Name: bioC [H]

Synonym: Paes_2187

Alternate gene names: 194334976

Gene position: 2360878-2360072 (Counterclockwise)

Preceding gene: 194334977

Following gene: 194334975

Centisome position: 93.95

GC content: 54.65

Gene sequence:

>807_bases
ATGCAGCAGTTGAACAAGACATTGATCCGGCAGCGTTTCGGGCGTCAGCTGCATGGTTATAACCGACACGCATTTATCCA
GAAGAAGATGGCCGGGCATCTGGCCGATATGGTGAGCGCATCGCTTGCATCGTCTGAGGTCGGTCGTTTGTTTGAAATAG
GCGTCGGCTCTGCTGCATTGACAGACGCGCTGCTCCATCGTTTGCGTATCGACCGTTACTATGCCAATGATCTGGTTCCG
CAATGCCGACAGATGGTGGAAACAGTTACTGCGCTTCATGGCGTAGATTCTGCCGAGTTTCTTGATGGCGATATAGAGGC
GCTTCGGGAGATTCCCGGAGATCTTGATGTCATTGTTTCCGGGGCGACCGTTCAGTGGCTTGAAGACCTGCCAGGGTTTT
TCCATCGTATGGCAGGCGCGCTCAAGCCCGGGGGAGTGCTTGCTTTCAGCACTTTCGGACATGATAATATGCAGGAGATT
CGCGCGCTTGAATCTGTTGGCTTGCACTACCATACCCTGGCAGAGATGCAGGCAATGGCAGGAGAGCTCTATGAGGTTAC
CGGTATGGAGGAGGAGCGCCATCAGCTTGATTTCACTGGTCCGGAAGCAGTACTTCGCCATATCAGTCGGACTGGCGTCA
ATGGTCTTGATGGCCGCGCATGGACGAAGAGCCGCCACAGGGCTTTTATCGATCGCTACCGGCGTGCGTTTTCGTCGGGC
GATGGCGTGCGCCTGACCTATCATACGATGTATTGCTGTTTCAGGAAATGCCCTGCTTCGGCTGGCGTTGAAGCGACGTG
CTGCTGA

Upstream 100 bases:

>100_bases
ATGCCCAGAAAAGGGCGTGGCGTGATCTGCCGTTGACCGTTGTGGAGACAATGCCGCATGTTCCGTTTTTCCATCTCAAA
GGCTGGCACGAGGTGATGGC

Downstream 100 bases:

>100_bases
TGTCGCCATGCCGGGTTCAGAAATTCAATAAATCAACAGTTCAACATGTTTCAATGATCATAGCGGTCAGTGGTATCGAT
ACAGGGATAGGAAAGACCAT

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQQLNKTLIRQRFGRQLHGYNRHAFIQKKMAGHLADMVSASLASSEVGRLFEIGVGSAALTDALLHRLRIDRYYANDLVP
QCRQMVETVTALHGVDSAEFLDGDIEALREIPGDLDVIVSGATVQWLEDLPGFFHRMAGALKPGGVLAFSTFGHDNMQEI
RALESVGLHYHTLAEMQAMAGELYEVTGMEEERHQLDFTGPEAVLRHISRTGVNGLDGRAWTKSRHRAFIDRYRRAFSSG
DGVRLTYHTMYCCFRKCPASAGVEATCC

Sequences:

>Translated_268_residues
MQQLNKTLIRQRFGRQLHGYNRHAFIQKKMAGHLADMVSASLASSEVGRLFEIGVGSAALTDALLHRLRIDRYYANDLVP
QCRQMVETVTALHGVDSAEFLDGDIEALREIPGDLDVIVSGATVQWLEDLPGFFHRMAGALKPGGVLAFSTFGHDNMQEI
RALESVGLHYHTLAEMQAMAGELYEVTGMEEERHQLDFTGPEAVLRHISRTGVNGLDGRAWTKSRHRAFIDRYRRAFSSG
DGVRLTYHTMYCCFRKCPASAGVEATCC
>Mature_268_residues
MQQLNKTLIRQRFGRQLHGYNRHAFIQKKMAGHLADMVSASLASSEVGRLFEIGVGSAALTDALLHRLRIDRYYANDLVP
QCRQMVETVTALHGVDSAEFLDGDIEALREIPGDLDVIVSGATVQWLEDLPGFFHRMAGALKPGGVLAFSTFGHDNMQEI
RALESVGLHYHTLAEMQAMAGELYEVTGMEEERHQLDFTGPEAVLRHISRTGVNGLDGRAWTKSRHRAFIDRYRRAFSSG
DGVRLTYHTMYCCFRKCPASAGVEATCC

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29873; Mature: 29873

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLNKTLIRQRFGRQLHGYNRHAFIQKKMAGHLADMVSASLASSEVGRLFEIGVGSAAL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TDALLHRLRIDRYYANDLVPQCRQMVETVTALHGVDSAEFLDGDIEALREIPGDLDVIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHCCCCCEEEEC
GATVQWLEDLPGFFHRMAGALKPGGVLAFSTFGHDNMQEIRALESVGLHYHTLAEMQAMA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
GELYEVTGMEEERHQLDFTGPEAVLRHISRTGVNGLDGRAWTKSRHRAFIDRYRRAFSSG
HHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DGVRLTYHTMYCCFRKCPASAGVEATCC
CCCEEHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQQLNKTLIRQRFGRQLHGYNRHAFIQKKMAGHLADMVSASLASSEVGRLFEIGVGSAAL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TDALLHRLRIDRYYANDLVPQCRQMVETVTALHGVDSAEFLDGDIEALREIPGDLDVIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHCCCCCEEEEC
GATVQWLEDLPGFFHRMAGALKPGGVLAFSTFGHDNMQEIRALESVGLHYHTLAEMQAMA
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
GELYEVTGMEEERHQLDFTGPEAVLRHISRTGVNGLDGRAWTKSRHRAFIDRYRRAFSSG
HHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DGVRLTYHTMYCCFRKCPASAGVEATCC
CCCEEHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]