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The map label for this gene is gmhB [H]

Identifier: 194334816

GI number: 194334816

Start: 2217043

End: 2217639

Strand: Reverse

Name: gmhB [H]

Synonym: Paes_2019

Alternate gene names: 194334816

Gene position: 2217639-2217043 (Counterclockwise)

Preceding gene: 194334817

Following gene: 194334815

Centisome position: 88.25

GC content: 51.59

Gene sequence:

>597_bases
GTGCTCAGAAAGATTAAGGTCTTATTTCTTGACAGAGACGGTACGATCAATCACGATATCGGAACCTATGTTACATCGCG
CCAGCAGTTTCGTCTGATCGACAGGGCTGCTGAAGCGGTCAGGGTGGCAAAAGCTGCTGGTTTTGAGATCGTGATTGTGA
CTAATCAGGCAGGGATTGCAAAGGGGATCGTCACTCCTGAAGCGATTGATGATGTTCATGAGTACATGCGGGATTTGTTT
TGCCTCGACAACGCCTCGTTCGACAGGGTGTATTACTGCCCATCCCATCCGGACTATCCTCATCCGCTCTACGATCGTTT
CAGCGACTGTCGGAAACCCGGAACCGGTATGGTTGAGCGTGCAATTGCCGAATACCGGGCGTGCGGTTGTGAGGTGGACC
TTGGCCATTCGTTTTTCATAGGCGACAAAACTATCGATGTCGAATGTGCTCTGCGTGCAGGGCTCCGGCCTGTTCTCGTG
AGGACCGGTCATGGAGAGGAGTCGCTCTGCAGGGAGAAAAACCTTCTTCCCGAATATGTTGCCGATGACCTTTACGATGC
CGTTGCCGGTTATATCCTTTCACAACAGCTCACTTGA

Upstream 100 bases:

>100_bases
CGCATTGTTACCGGTAATATGGTCCGGGACCTGACATGGAAAAATTCCGCTGCAAAGTACAATGAGCTCTATCAGGGGGT
TCGCGGGGGTGAGTGATCAG

Downstream 100 bases:

>100_bases
CTCGCCTGACACTCCCGGGATGCTTCACTGTTACGTCCATATTCCTTTCTGCAGAAACCGCTGCAGCTACTGTGACTTTT
TCCTGATAACCCGCGAGGGA

Product: histidinol-phosphate phosphatase family protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MLRKIKVLFLDRDGTINHDIGTYVTSRQQFRLIDRAAEAVRVAKAAGFEIVIVTNQAGIAKGIVTPEAIDDVHEYMRDLF
CLDNASFDRVYYCPSHPDYPHPLYDRFSDCRKPGTGMVERAIAEYRACGCEVDLGHSFFIGDKTIDVECALRAGLRPVLV
RTGHGEESLCREKNLLPEYVADDLYDAVAGYILSQQLT

Sequences:

>Translated_198_residues
MLRKIKVLFLDRDGTINHDIGTYVTSRQQFRLIDRAAEAVRVAKAAGFEIVIVTNQAGIAKGIVTPEAIDDVHEYMRDLF
CLDNASFDRVYYCPSHPDYPHPLYDRFSDCRKPGTGMVERAIAEYRACGCEVDLGHSFFIGDKTIDVECALRAGLRPVLV
RTGHGEESLCREKNLLPEYVADDLYDAVAGYILSQQLT
>Mature_198_residues
MLRKIKVLFLDRDGTINHDIGTYVTSRQQFRLIDRAAEAVRVAKAAGFEIVIVTNQAGIAKGIVTPEAIDDVHEYMRDLF
CLDNASFDRVYYCPSHPDYPHPLYDRFSDCRKPGTGMVERAIAEYRACGCEVDLGHSFFIGDKTIDVECALRAGLRPVLV
RTGHGEESLCREKNLLPEYVADDLYDAVAGYILSQQLT

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=187, Percent_Identity=36.3636363636364, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082027, Length=157, Percent_Identity=31.2101910828025, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 22236; Mature: 22236

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKIKVLFLDRDGTINHDIGTYVTSRQQFRLIDRAAEAVRVAKAAGFEIVIVTNQAGIA
CCCEEEEEEEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCH
KGIVTPEAIDDVHEYMRDLFCLDNASFDRVYYCPSHPDYPHPLYDRFSDCRKPGTGMVER
HCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHH
AIAEYRACGCEVDLGHSFFIGDKTIDVECALRAGLRPVLVRTGHGEESLCREKNLLPEYV
HHHHHHHCCCEEECCCEEEECCCEEEHHHHHHCCCCEEEEECCCCHHHHHHHHCCCHHHH
ADDLYDAVAGYILSQQLT
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRKIKVLFLDRDGTINHDIGTYVTSRQQFRLIDRAAEAVRVAKAAGFEIVIVTNQAGIA
CCCEEEEEEEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCH
KGIVTPEAIDDVHEYMRDLFCLDNASFDRVYYCPSHPDYPHPLYDRFSDCRKPGTGMVER
HCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHH
AIAEYRACGCEVDLGHSFFIGDKTIDVECALRAGLRPVLVRTGHGEESLCREKNLLPEYV
HHHHHHHCCCEEECCCEEEECCCEEEHHHHHHCCCCEEEEECCCCHHHHHHHHCCCHHHH
ADDLYDAVAGYILSQQLT
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]