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The map label for this gene is comF [H]

Identifier: 194334811

GI number: 194334811

Start: 2210717

End: 2211409

Strand: Reverse

Name: comF [H]

Synonym: Paes_2014

Alternate gene names: 194334811

Gene position: 2211409-2210717 (Counterclockwise)

Preceding gene: 194334812

Following gene: 194334810

Centisome position: 88.0

GC content: 52.96

Gene sequence:

>693_bases
ATGATGATTCAGGAGCTTTTGCATCTTGTCTATCCCCGCGTGTGCGTCTCCTGTGGAACGCTGCTTCAGCAACCGGAGCA
GTCAATATGTACCACTTGTCTTCGATCGTTTGATGCGTTTCATGACGCAGCAGCTTCAGGAGATGCTGTCCGGGAGGTGC
TGCGTCGCCACTATCCTTCCGCTCCACTGCCTGCTGCTGCAACCGTGCTGTACCGGTTTCATCGCGATGACGGTTTGCAG
ACAGCCCTTCACGCTATGAAGTACAGAGGGGTTTTTCAATTATGCAATCTGTTTGGTGCTCTTCTGGCAACGAAAATTGC
CGGGGATTCGTCGGCAGAAGATATCGGCGCGGTTGTTGCAGTGCCGCTGCACAAGCTGAAAAAAATATCGAGGACCTATA
ATCAGTCCGAGCTTATTGCGCGTGTGATAGGCCGCCAATGTCGGCTTGCGGTCGAGAGCCGTCTGATCGGCAGAACAAAA
TATACTGTTTCGCAGACCGGTCTTTCTGCAAAAGAGCGCCGCACGAATGTTATCGATGCGTTTTCGCCGGCAGGAAAACC
TGTCCCCGCTCATGTGCTTCTTGTCGATGATGTGATGACAACCGGTTCGACGGTTGCCGCGGCGATGGATGTGCTTGCTC
AATGCGGTGCGCAAAAAATTTCTCTTGCAATCGTGGCTCTTGCCACCTCCTGA

Upstream 100 bases:

>100_bases
ATGCATGATGACCTTGAAGTGATCAGAGCGTCATTAGGGAACGATGCCGGAGTCTATGGAGCCGCGGCACTCTGTTTCGA
GAGTCCATAATTCGGGGCTG

Downstream 100 bases:

>100_bases
AAAAAACATGTTATGGATCTTTTCTACACACCGCCGGAATGTATTGATCTGACGGCACGCACGCTTGTTGTCGAGGGAGA
AGAGTTTTTCCATATTGTTC

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MMIQELLHLVYPRVCVSCGTLLQQPEQSICTTCLRSFDAFHDAAASGDAVREVLRRHYPSAPLPAAATVLYRFHRDDGLQ
TALHAMKYRGVFQLCNLFGALLATKIAGDSSAEDIGAVVAVPLHKLKKISRTYNQSELIARVIGRQCRLAVESRLIGRTK
YTVSQTGLSAKERRTNVIDAFSPAGKPVPAHVLLVDDVMTTGSTVAAAMDVLAQCGAQKISLAIVALATS

Sequences:

>Translated_230_residues
MMIQELLHLVYPRVCVSCGTLLQQPEQSICTTCLRSFDAFHDAAASGDAVREVLRRHYPSAPLPAAATVLYRFHRDDGLQ
TALHAMKYRGVFQLCNLFGALLATKIAGDSSAEDIGAVVAVPLHKLKKISRTYNQSELIARVIGRQCRLAVESRLIGRTK
YTVSQTGLSAKERRTNVIDAFSPAGKPVPAHVLLVDDVMTTGSTVAAAMDVLAQCGAQKISLAIVALATS
>Mature_230_residues
MMIQELLHLVYPRVCVSCGTLLQQPEQSICTTCLRSFDAFHDAAASGDAVREVLRRHYPSAPLPAAATVLYRFHRDDGLQ
TALHAMKYRGVFQLCNLFGALLATKIAGDSSAEDIGAVVAVPLHKLKKISRTYNQSELIARVIGRQCRLAVESRLIGRTK
YTVSQTGLSAKERRTNVIDAFSPAGKPVPAHVLLVDDVMTTGSTVAAAMDVLAQCGAQKISLAIVALATS

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=105, Percent_Identity=35.2380952380952, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 24790; Mature: 24790

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIQELLHLVYPRVCVSCGTLLQQPEQSICTTCLRSFDAFHDAAASGDAVREVLRRHYPS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
APLPAAATVLYRFHRDDGLQTALHAMKYRGVFQLCNLFGALLATKIAGDSSAEDIGAVVA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VPLHKLKKISRTYNQSELIARVIGRQCRLAVESRLIGRTKYTVSQTGLSAKERRTNVIDA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
FSPAGKPVPAHVLLVDDVMTTGSTVAAAMDVLAQCGAQKISLAIVALATS
CCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHCCCHHHHHHHEEEECC
>Mature Secondary Structure
MMIQELLHLVYPRVCVSCGTLLQQPEQSICTTCLRSFDAFHDAAASGDAVREVLRRHYPS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
APLPAAATVLYRFHRDDGLQTALHAMKYRGVFQLCNLFGALLATKIAGDSSAEDIGAVVA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VPLHKLKKISRTYNQSELIARVIGRQCRLAVESRLIGRTKYTVSQTGLSAKERRTNVIDA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
FSPAGKPVPAHVLLVDDVMTTGSTVAAAMDVLAQCGAQKISLAIVALATS
CCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHCCCHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]