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The map label for this gene is glcK [H]

Identifier: 194334812

GI number: 194334812

Start: 2211420

End: 2212412

Strand: Reverse

Name: glcK [H]

Synonym: Paes_2015

Alternate gene names: 194334812

Gene position: 2212412-2211420 (Counterclockwise)

Preceding gene: 194334813

Following gene: 194334811

Centisome position: 88.04

GC content: 55.29

Gene sequence:

>993_bases
ATGCGTATGGCGTGGGCGATAGGTATAGATCTTGGCGGTACTGCGGTAAAAATTGCGCTCATTGATCGTCATACCGGTAT
TGCAGACCACGAGCGTCATGCAACCAGACTCGATGCCGGCCCTGAAGGCGTTATTGAGCAGATTGCCGCTCTTGCCTGTG
CAAGCTATCACAGAGGTGTTGATCGGTTTGGCCCGGATAGTTTTGCCGGCATAGGGCTTGGTGCTCCGGGAGGCGTTGAC
AGCACTCGCGGTATCCTCTCCTATCCTCCGAATCTTCCCGGCTGGACCCGCTATCCTCTGCGCGATGCGCTCCGCAAAGC
CCTGGAACAGGAGATCTTGAGTCTGCCCGCGCTCATGGTTGACAACGATGCCAACGCGGCAGCATTAGGAGAGGCATATT
TTGGTGCCGGTCAAACCTTCAGCGATTTTATGCTGGTGACGCTTGGTACGGGTGTTGGTGGCGGCATTATTCTCAATCGG
GCGCTCTATCGCGGTTCTCACGGAACGGCAGGTGAAATCGGTTTTATGACAATCGATTATCGGGGCCAAAGTGTTCATGC
CGGGGTCAGGGGGACGCTTGAAGGTCTTATAGGCAAAGAAAAAATTGTTACGCTTGCCAAAGAGCGCTACCGTGAGCATC
CCCGGAAGCTGTGGTCTCCACAACATCACGGGGAGGATCTCTCCCTGCTTTCCCCAAGGACGCTTGAGCATGCTGCCCAT
TCAGGAGACGCGATTGCCATGTCGATATGGCGGGAAGTCGGTTCAATTCTTGGTGTGGGCCTTGCCGGTGTTGTTGCGCT
TCTCGATATCCGGAAGTTTGTGATTGGCGGTGGTATTTCTGCCGCCGGGGACCTGGTTATTGTACCGGCTCTCGATCGGA
TACGCCACTCCACGCTGCCGTCGATGCATGATGACCTTGAAGTGATCAGAGCGTCATTAGGGAACGATGCCGGAGTCTAT
GGAGCCGCGGCACTCTGTTTCGAGAGTCCATAA

Upstream 100 bases:

>100_bases
CTGTGAAGAAAGTCCTGAACGTGACGAGATATTGGCGTTTTTCGATACCAGTTCGGCCAGAAGAAAGTATATCCGACCCT
ATAATTCTTAACCGTTAGAG

Downstream 100 bases:

>100_bases
TTCGGGGCTGATGATGATTCAGGAGCTTTTGCATCTTGTCTATCCCCGCGTGTGCGTCTCCTGTGGAACGCTGCTTCAGC
AACCGGAGCAGTCAATATGT

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRMAWAIGIDLGGTAVKIALIDRHTGIADHERHATRLDAGPEGVIEQIAALACASYHRGVDRFGPDSFAGIGLGAPGGVD
STRGILSYPPNLPGWTRYPLRDALRKALEQEILSLPALMVDNDANAAALGEAYFGAGQTFSDFMLVTLGTGVGGGIILNR
ALYRGSHGTAGEIGFMTIDYRGQSVHAGVRGTLEGLIGKEKIVTLAKERYREHPRKLWSPQHHGEDLSLLSPRTLEHAAH
SGDAIAMSIWREVGSILGVGLAGVVALLDIRKFVIGGGISAAGDLVIVPALDRIRHSTLPSMHDDLEVIRASLGNDAGVY
GAAALCFESP

Sequences:

>Translated_330_residues
MRMAWAIGIDLGGTAVKIALIDRHTGIADHERHATRLDAGPEGVIEQIAALACASYHRGVDRFGPDSFAGIGLGAPGGVD
STRGILSYPPNLPGWTRYPLRDALRKALEQEILSLPALMVDNDANAAALGEAYFGAGQTFSDFMLVTLGTGVGGGIILNR
ALYRGSHGTAGEIGFMTIDYRGQSVHAGVRGTLEGLIGKEKIVTLAKERYREHPRKLWSPQHHGEDLSLLSPRTLEHAAH
SGDAIAMSIWREVGSILGVGLAGVVALLDIRKFVIGGGISAAGDLVIVPALDRIRHSTLPSMHDDLEVIRASLGNDAGVY
GAAALCFESP
>Mature_330_residues
MRMAWAIGIDLGGTAVKIALIDRHTGIADHERHATRLDAGPEGVIEQIAALACASYHRGVDRFGPDSFAGIGLGAPGGVD
STRGILSYPPNLPGWTRYPLRDALRKALEQEILSLPALMVDNDANAAALGEAYFGAGQTFSDFMLVTLGTGVGGGIILNR
ALYRGSHGTAGEIGFMTIDYRGQSVHAGVRGTLEGLIGKEKIVTLAKERYREHPRKLWSPQHHGEDLSLLSPRTLEHAAH
SGDAIAMSIWREVGSILGVGLAGVVALLDIRKFVIGGGISAAGDLVIVPALDRIRHSTLPSMHDDLEVIRASLGNDAGVY
GAAALCFESP

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=307, Percent_Identity=29.3159609120521, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI190014632, Length=307, Percent_Identity=29.3159609120521, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI298566325, Length=307, Percent_Identity=29.3159609120521, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4885285, Length=307, Percent_Identity=29.3159609120521, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786891, Length=333, Percent_Identity=28.8288288288288, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787878, Length=258, Percent_Identity=28.2945736434109, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787363, Length=328, Percent_Identity=26.5243902439024, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87081733, Length=333, Percent_Identity=27.9279279279279, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34848; Mature: 34848

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMAWAIGIDLGGTAVKIALIDRHTGIADHERHATRLDAGPEGVIEQIAALACASYHRGV
CCEEEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCH
DRFGPDSFAGIGLGAPGGVDSTRGILSYPPNLPGWTRYPLRDALRKALEQEILSLPALMV
HHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DNDANAAALGEAYFGAGQTFSDFMLVTLGTGVGGGIILNRALYRGSHGTAGEIGFMTIDY
ECCCCHHHHHHHHHCCCCCHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEC
RGQSVHAGVRGTLEGLIGKEKIVTLAKERYREHPRKLWSPQHHGEDLSLLSPRTLEHAAH
CCCEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHC
SGDAIAMSIWREVGSILGVGLAGVVALLDIRKFVIGGGISAAGDLVIVPALDRIRHSTLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHCCC
SMHDDLEVIRASLGNDAGVYGAAALCFESP
CHHHHHHHHHHHHCCCCCHHHHHHEEECCC
>Mature Secondary Structure
MRMAWAIGIDLGGTAVKIALIDRHTGIADHERHATRLDAGPEGVIEQIAALACASYHRGV
CCEEEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCH
DRFGPDSFAGIGLGAPGGVDSTRGILSYPPNLPGWTRYPLRDALRKALEQEILSLPALMV
HHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DNDANAAALGEAYFGAGQTFSDFMLVTLGTGVGGGIILNRALYRGSHGTAGEIGFMTIDY
ECCCCHHHHHHHHHCCCCCHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEC
RGQSVHAGVRGTLEGLIGKEKIVTLAKERYREHPRKLWSPQHHGEDLSLLSPRTLEHAAH
CCCEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHC
SGDAIAMSIWREVGSILGVGLAGVVALLDIRKFVIGGGISAAGDLVIVPALDRIRHSTLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHCCC
SMHDDLEVIRASLGNDAGVYGAAALCFESP
CHHHHHHHHHHHHCCCCCHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]