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The map label for this gene is 194334761

Identifier: 194334761

GI number: 194334761

Start: 2143808

End: 2145025

Strand: Reverse

Name: 194334761

Synonym: Paes_1962

Alternate gene names: NA

Gene position: 2145025-2143808 (Counterclockwise)

Preceding gene: 194334765

Following gene: 194334760

Centisome position: 85.36

GC content: 47.78

Gene sequence:

>1218_bases
ATGCGTATTTTAACTTTTACAGGTAAAGGCGGGGTTGGAAAAACCAGTGTTTCAGCAGCGACAGCTGTCCGGCTATCCCA
GCTTGGGTACCGTACTCTGGTACTGTCGACGGATCCTGCCCACAGTCTCTCGGATTCTTTTAATCTTTCTCTGGGGGCTG
AACCTACCAAGATCAAGGAGAATTTGCATGCTATTGAAGTCAATCCCTATGTTGATTTAAAAGAAAACTGGCAGGCTGTC
CAGAAATATTATACCAGAGTGTTTGCGGCTCAGGGCGTTTCGGGCGTTGTTGCTGATGAAATGACGATTCTTCCCGGTAT
GGAAGAACTTTTTTCTCTGCTGAGAATTAAACGATATAAGTCAGCCGGTCTCTACGATGCGCTTGTTCTCGATACTGCTC
CAACCGGTGAAACACTGCGATTGCTCTCCCTTCCGGACACCTTGTCCTGGGGAATGAAAGCGGTGAAAAATGTCAATAAG
TACATTATGAAGCCGCTCAGCAAGCCGCTTTCTAAAATGTCTGACAAGATTGCCTACTATATTCCTCCGGAAGATGCTAT
CGATTCAGTCGATCAGGTTTTCGACGAACTTGAGGATATCCGCGATATTCTTACCGATAATCTCAATTCGACGGTCAGGC
TCGTGATGAACGCCGAAAAAATGTCCATCAAGGAGACTATGCGCGCGCTGACCTATCTGAACCTCTACGGTTTCAATGTC
GATATGGTGCTGGTCAATAAAATGCTCGATACCCAGGAAGACAGCGGTTATCTTGAAAAGTGGAAGAGCATTCAGCAGAA
ATATCTTGGAGAGATTGAAGAAGGGTTCGCGCCGCTTCCTGTCAAGAAGCTGAAGATGTATGATCAGGAAATTGTCGGCC
TGGAGGCTCTTGAACGCTTCGCGAAGGATATGTATGGTGACGATGATCCGTCTGAAGTCGTCTACGACGAGCCGCCGATC
AAGTTCGAGCGCAGCGGTGATATTTATGAGGTGCAGTTGAAGCTCATGTTTGCCAACCCTGTCGATATCGATGTCTGGGT
AACGGGGGATGAACTGTTTGTGCAGATTGGAAGCCAGCGCAAGATTATCACGCTGCCGATCAGTCTCACCGGTCTCGATC
CGGGCGATGCGGTATTCAAGGACAAATGGCTGCATATTCCCTTTGACCTGAACCGTCAGGGGCAGCATCAGAACAGGAAA
GAGTATAACAAAGTGTAG

Upstream 100 bases:

>100_bases
TCTTGTGAAGAAGTTTCACCTTTTGTAGAGTCAGTCGAGAGTTATATCTTGTGTCTTTTCTCTACGGCAAATCGATCTCA
TAAAATCCAATGCTTGGTTC

Downstream 100 bases:

>100_bases
CCTCCAGTTGCCGGTATCGGTCCTGTTTGACATGAAGGCGAATTTTGTTACTTTCATAGAACGTTTTATTGTCATTACTA
AACAACGTAAACTGGCTCTC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSFNLSLGAEPTKIKENLHAIEVNPYVDLKENWQAV
QKYYTRVFAAQGVSGVVADEMTILPGMEELFSLLRIKRYKSAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIMKPLSKPLSKMSDKIAYYIPPEDAIDSVDQVFDELEDIRDILTDNLNSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
DMVLVNKMLDTQEDSGYLEKWKSIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLEALERFAKDMYGDDDPSEVVYDEPPI
KFERSGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGSQRKIITLPISLTGLDPGDAVFKDKWLHIPFDLNRQGQHQNRK
EYNKV

Sequences:

>Translated_405_residues
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSFNLSLGAEPTKIKENLHAIEVNPYVDLKENWQAV
QKYYTRVFAAQGVSGVVADEMTILPGMEELFSLLRIKRYKSAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIMKPLSKPLSKMSDKIAYYIPPEDAIDSVDQVFDELEDIRDILTDNLNSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
DMVLVNKMLDTQEDSGYLEKWKSIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLEALERFAKDMYGDDDPSEVVYDEPPI
KFERSGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGSQRKIITLPISLTGLDPGDAVFKDKWLHIPFDLNRQGQHQNRK
EYNKV
>Mature_405_residues
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSFNLSLGAEPTKIKENLHAIEVNPYVDLKENWQAV
QKYYTRVFAAQGVSGVVADEMTILPGMEELFSLLRIKRYKSAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNK
YIMKPLSKPLSKMSDKIAYYIPPEDAIDSVDQVFDELEDIRDILTDNLNSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
DMVLVNKMLDTQEDSGYLEKWKSIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLEALERFAKDMYGDDDPSEVVYDEPPI
KFERSGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGSQRKIITLPISLTGLDPGDAVFKDKWLHIPFDLNRQGQHQNRK
EYNKV

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=290, Percent_Identity=26.2068965517241, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17557003, Length=304, Percent_Identity=26.3157894736842, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320103, Length=326, Percent_Identity=28.5276073619632, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24586297, Length=306, Percent_Identity=28.7581699346405, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 45789; Mature: 45789

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSFNLSLGAEPTKIKE
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEECCCCCHHHHC
NLHAIEVNPYVDLKENWQAVQKYYTRVFAAQGVSGVVADEMTILPGMEELFSLLRIKRYK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHH
SAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIMKPLSKPLSKMSDKIAYY
CCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IPPEDAIDSVDQVFDELEDIRDILTDNLNSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCC
DMVLVNKMLDTQEDSGYLEKWKSIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLEALERF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AKDMYGDDDPSEVVYDEPPIKFERSGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGSQR
HHHHCCCCCCCCCEECCCCCCEECCCCEEEEEEEEEEECCCEEEEEEECCCEEEEECCCC
KIITLPISLTGLDPGDAVFKDKWLHIPFDLNRQGQHQNRKEYNKV
EEEEEEEEEECCCCCCCHHCCCEEECCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MRILTFTGKGGVGKTSVSAATAVRLSQLGYRTLVLSTDPAHSLSDSFNLSLGAEPTKIKE
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEECCCCCHHHHC
NLHAIEVNPYVDLKENWQAVQKYYTRVFAAQGVSGVVADEMTILPGMEELFSLLRIKRYK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHHHHHHHHHHHH
SAGLYDALVLDTAPTGETLRLLSLPDTLSWGMKAVKNVNKYIMKPLSKPLSKMSDKIAYY
CCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IPPEDAIDSVDQVFDELEDIRDILTDNLNSTVRLVMNAEKMSIKETMRALTYLNLYGFNV
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCC
DMVLVNKMLDTQEDSGYLEKWKSIQQKYLGEIEEGFAPLPVKKLKMYDQEIVGLEALERF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AKDMYGDDDPSEVVYDEPPIKFERSGDIYEVQLKLMFANPVDIDVWVTGDELFVQIGSQR
HHHHCCCCCCCCCEECCCCCCEECCCCEEEEEEEEEEECCCEEEEEEECCCEEEEECCCC
KIITLPISLTGLDPGDAVFKDKWLHIPFDLNRQGQHQNRKEYNKV
EEEEEEEEEECCCCCCCHHCCCEEECCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]