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The map label for this gene is cysQ [H]

Identifier: 194334554

GI number: 194334554

Start: 1909919

End: 1910710

Strand: Reverse

Name: cysQ [H]

Synonym: Paes_1750

Alternate gene names: 194334554

Gene position: 1910710-1909919 (Counterclockwise)

Preceding gene: 194334555

Following gene: 194334553

Centisome position: 76.04

GC content: 53.16

Gene sequence:

>792_bases
ATGAGTGCATCACTGCTGACAGAGTCGCTTGTTCAGACAGCCATAGATGCTGCGCTCAAGGCTGGTGCCGAGATACTGGG
GATATATAGCCGGGATGATCACGGTGTTGAGCTCAAGGGCGATGACTCACCGTTGACGCTGGCTGACAAGGCAGCGCATA
GGGTGATCATGCAGATGCTTCAGGACACAGCTTTGCCGGTGCTGAGTGAAGAGGGGCGCAATATTCCTTATGTTGAGCGT
GCACAGTGGGAACGGTTCTGGATGGTTGATCCCCTTGACGGGACCAAGGAGTTTATTTCCAGGAACGGAGAGTTTACGGT
GAACATTGCGCTGGTCGAGCATGGCAAGCCTGTGATGGGTGTGGTGTATGTGCCGGTACTCGATGAGTTGTATGTTGGTA
AGGCGGGGCGGGGCGCGCTGTTGATTCGCAATGCTGCTGCTGAACCATGGGAAACGGTAACGTTACCTTGTGGTGCTGCT
GGTGATGGTGTGTATCGTGTGGTTGGTAGTCGTTCCCATCTTAATGATGAGACGCTTGCGTTTGTGGAAGAGCTTCGTGC
TGAGCATCCGGAGATTGAGATGGTGCAGCGGGGAAGTTCGCTGAAAATCTGCATGGTGGCAGCCGGTGATGCCGATTGCT
ATCCACGGTTCGGCCTTACCATGGAGTGGGATACTGCGGCTGGGCATGCTGTTGTGAATGCTGCGGGAAAACGAATGGTT
ATTGCCGGCAGTGATGATGAGGTGCGGTATAATAAGGAGGATCTGTTGAATCCGTTTTTTATTGTTAGGTGA

Upstream 100 bases:

>100_bases
ATGATTGTCCTGTTAAGGCTGCTGTTACTGTTGACCAGCGGCATGTCGGGGTTGATCCTGAAGAGGTGGTAAGCTACATG
CTGGCACAGGGGGTGATACG

Downstream 100 bases:

>100_bases
TCTTGATTCAGTAGCCGGTATCCGGTATTCATTTCTCCTGCGTTCTTGTCATTCATTTATTTATCATGCTCTCCTTCGAA
TCCCTCATTGTTTTTTCCGC

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSASLLTESLVQTAIDAALKAGAEILGIYSRDDHGVELKGDDSPLTLADKAAHRVIMQMLQDTALPVLSEEGRNIPYVER
AQWERFWMVDPLDGTKEFISRNGEFTVNIALVEHGKPVMGVVYVPVLDELYVGKAGRGALLIRNAAAEPWETVTLPCGAA
GDGVYRVVGSRSHLNDETLAFVEELRAEHPEIEMVQRGSSLKICMVAAGDADCYPRFGLTMEWDTAAGHAVVNAAGKRMV
IAGSDDEVRYNKEDLLNPFFIVR

Sequences:

>Translated_263_residues
MSASLLTESLVQTAIDAALKAGAEILGIYSRDDHGVELKGDDSPLTLADKAAHRVIMQMLQDTALPVLSEEGRNIPYVER
AQWERFWMVDPLDGTKEFISRNGEFTVNIALVEHGKPVMGVVYVPVLDELYVGKAGRGALLIRNAAAEPWETVTLPCGAA
GDGVYRVVGSRSHLNDETLAFVEELRAEHPEIEMVQRGSSLKICMVAAGDADCYPRFGLTMEWDTAAGHAVVNAAGKRMV
IAGSDDEVRYNKEDLLNPFFIVR
>Mature_262_residues
SASLLTESLVQTAIDAALKAGAEILGIYSRDDHGVELKGDDSPLTLADKAAHRVIMQMLQDTALPVLSEEGRNIPYVERA
QWERFWMVDPLDGTKEFISRNGEFTVNIALVEHGKPVMGVVYVPVLDELYVGKAGRGALLIRNAAAEPWETVTLPCGAAG
DGVYRVVGSRSHLNDETLAFVEELRAEHPEIEMVQRGSSLKICMVAAGDADCYPRFGLTMEWDTAAGHAVVNAAGKRMVI
AGSDDEVRYNKEDLLNPFFIVR

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=218, Percent_Identity=45.4128440366972, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788882, Length=235, Percent_Identity=30.6382978723404, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320493, Length=158, Percent_Identity=30.379746835443, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28744; Mature: 28613

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASLLTESLVQTAIDAALKAGAEILGIYSRDDHGVELKGDDSPLTLADKAAHRVIMQML
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHH
QDTALPVLSEEGRNIPYVERAQWERFWMVDPLDGTKEFISRNGEFTVNIALVEHGKPVMG
HHHCCCHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCEEE
VVYVPVLDELYVGKAGRGALLIRNAAAEPWETVTLPCGAAGDGVYRVVGSRSHLNDETLA
EEEECHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHH
FVEELRAEHPEIEMVQRGSSLKICMVAAGDADCYPRFGLTMEWDTAAGHAVVNAAGKRMV
HHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCEEEECCCCEEE
IAGSDDEVRYNKEDLLNPFFIVR
EECCCCCEEECHHHHCCCEEEEC
>Mature Secondary Structure 
SASLLTESLVQTAIDAALKAGAEILGIYSRDDHGVELKGDDSPLTLADKAAHRVIMQML
CHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHH
QDTALPVLSEEGRNIPYVERAQWERFWMVDPLDGTKEFISRNGEFTVNIALVEHGKPVMG
HHHCCCHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCEEE
VVYVPVLDELYVGKAGRGALLIRNAAAEPWETVTLPCGAAGDGVYRVVGSRSHLNDETLA
EEEECHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHH
FVEELRAEHPEIEMVQRGSSLKICMVAAGDADCYPRFGLTMEWDTAAGHAVVNAAGKRMV
HHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCEEEECCCCEEE
IAGSDDEVRYNKEDLLNPFFIVR
EECCCCCEEECHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]