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The map label for this gene is gmhB [H]

Identifier: 194334548

GI number: 194334548

Start: 1904203

End: 1904766

Strand: Reverse

Name: gmhB [H]

Synonym: Paes_1743

Alternate gene names: 194334548

Gene position: 1904766-1904203 (Counterclockwise)

Preceding gene: 194334549

Following gene: 194334547

Centisome position: 75.8

GC content: 37.94

Gene sequence:

>564_bases
ATGGCATCGAGTGTTAGAGCGGCCTTTATTGATAGAGATGGCGTTATCAACGAGGAGCGTAATTATGTTTATAAAATTCA
GGATTTTGTTCTTCTTCCTGGTGTATTAGAGGCTTTAAAGATTTTTCAGGATACCGGTTTTCTATTAATTGTTGTTACAA
ATCAAGCAGGCATAGCTCGCGGGTATTATGATTCAAAAGCAGTTGAGGAACTCCATTTTTATATGAGATCATTGTTTAGT
GATTCGGGTATTATGATTGATAAAATTTATTATTGCCCGCATCACCGCGAGGGAATAGTAAAGAAATATGCGATTGATTG
TAATTGTCGTAAGCCTGCTCCTGGGATGTTAATTCAGGCAGTAAACGAATTTAATATAAATACAGCTCAAAGTGTTCTGA
TAGGAGATAAAATCAGTGATATTCAGGCAGGGAGGCGTGCAGGTGTAGGATGTAATGTTTTGGTTGAGTCAGGTCATCCA
TTTGAGACTTCGACACGATTTCTTGCGGATTATGTTGTTGCTGATTTGCTTGCTGCTGCTCAACTTTTTTCAATGCGTAG
TTAA

Upstream 100 bases:

>100_bases
GTCAAGAAAGGTAATCTTAAATTCTGTGAGGTCTCAGGTCCATTTGTTGATATTGGTGTTCCTTCAGATTATTATTCTTT
TCAAGCACAACATAAATATT

Downstream 100 bases:

>100_bases
CTATTAAATTTTATAATAATTCAATTATGCCTATTTATCGATCACGCGCTCCTTTACGACTCGGTCTAGCTGGAGGCGGT
ACAGATGTAAGCCCATTTAG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MASSVRAAFIDRDGVINEERNYVYKIQDFVLLPGVLEALKIFQDTGFLLIVVTNQAGIARGYYDSKAVEELHFYMRSLFS
DSGIMIDKIYYCPHHREGIVKKYAIDCNCRKPAPGMLIQAVNEFNINTAQSVLIGDKISDIQAGRRAGVGCNVLVESGHP
FETSTRFLADYVVADLLAAAQLFSMRS

Sequences:

>Translated_187_residues
MASSVRAAFIDRDGVINEERNYVYKIQDFVLLPGVLEALKIFQDTGFLLIVVTNQAGIARGYYDSKAVEELHFYMRSLFS
DSGIMIDKIYYCPHHREGIVKKYAIDCNCRKPAPGMLIQAVNEFNINTAQSVLIGDKISDIQAGRRAGVGCNVLVESGHP
FETSTRFLADYVVADLLAAAQLFSMRS
>Mature_186_residues
ASSVRAAFIDRDGVINEERNYVYKIQDFVLLPGVLEALKIFQDTGFLLIVVTNQAGIARGYYDSKAVEELHFYMRSLFSD
SGIMIDKIYYCPHHREGIVKKYAIDCNCRKPAPGMLIQAVNEFNINTAQSVLIGDKISDIQAGRRAGVGCNVLVESGHPF
ETSTRFLADYVVADLLAAAQLFSMRS

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=176, Percent_Identity=43.75, Blast_Score=163, Evalue=7e-42,
Organism=Escherichia coli, GI87082027, Length=149, Percent_Identity=30.2013422818792, Blast_Score=80, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20823; Mature: 20692

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSVRAAFIDRDGVINEERNYVYKIQDFVLLPGVLEALKIFQDTGFLLIVVTNQAGIAR
CCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
GYYDSKAVEELHFYMRSLFSDSGIMIDKIYYCPHHREGIVKKYAIDCNCRKPAPGMLIQA
CCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHH
VNEFNINTAQSVLIGDKISDIQAGRRAGVGCNVLVESGHPFETSTRFLADYVVADLLAAA
HHHCCCCCHHHEEECCCHHHHHCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QLFSMRS
HHHHCCC
>Mature Secondary Structure 
ASSVRAAFIDRDGVINEERNYVYKIQDFVLLPGVLEALKIFQDTGFLLIVVTNQAGIAR
CCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
GYYDSKAVEELHFYMRSLFSDSGIMIDKIYYCPHHREGIVKKYAIDCNCRKPAPGMLIQA
CCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHH
VNEFNINTAQSVLIGDKISDIQAGRRAGVGCNVLVESGHPFETSTRFLADYVVADLLAAA
HHHCCCCCHHHEEECCCHHHHHCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QLFSMRS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]