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The map label for this gene is mpg1 [H]

Identifier: 194334549

GI number: 194334549

Start: 1904750

End: 1905463

Strand: Reverse

Name: mpg1 [H]

Synonym: Paes_1744

Alternate gene names: 194334549

Gene position: 1905463-1904750 (Counterclockwise)

Preceding gene: 194334550

Following gene: 194334548

Centisome position: 75.83

GC content: 39.5

Gene sequence:

>714_bases
ATGAGTATTCCTTGCATTATTCTTGCTGGTGGTCTGGGTACTCGGTTACGTTCTGCTTTGCCAGATTTACCAAAATGCTT
AGCCCCTGTAGCTGGTCGTCCATTCTTGGAATGGCAGATGAAATCTCTTTTCAGACGAGGTATACATCACTTTGTTTTGG
CATTGGGCTATGGTGCTGATAAGATAATAGAGGTATTACACCAACCTTGGGCAAAGGAGATGTCTATTGATTATGTTATT
GAGAAAGAGCCGCTTGGCACTGGTGGAGCTATACGATTTGCGATGACAGATAAATTGATCGATGAAGTATTGGTTGTTAA
TGGTGATACTTTCTTAAATGGTGATCTTTCATCGCTTCTTGAACCTCTAAATAGAGGATCTGGCGAGTTCATGCGTATGG
CTGCAATTCATGTTTCTGATCGTTCGCGTTATGGTGGGGTTTTAGTTGATCAGGATAAGAACGTACTGGCATTTATAGAG
AAGGGTCGGCATGATTCTGGTTTGATAAATGCTGGAGTATATCACATTCATATTTCTGTTTTTGAGGAATATTTAATGCC
CTCATTTTCACTTGAGGCAGAAGTTATGCCAATATTGGTCAAGAAAGGTAATCTTAAATTCTGTGAGGTCTCAGGTCCAT
TTGTTGATATTGGTGTTCCTTCAGATTATTATTCTTTTCAAGCACAACATAAATATTATGGCATCGAGTGTTAG

Upstream 100 bases:

>100_bases
TTCATACACCGCGTATTCAGGAAAGCCATATTTTAATAGGACATATAATTTGTGCTGAAGTAGAACAACAAATATTTTCT
CATTTAGCACCTTCTCAGAA

Downstream 100 bases:

>100_bases
AGCGGCCTTTATTGATAGAGATGGCGTTATCAACGAGGAGCGTAATTATGTTTATAAAATTCAGGATTTTGTTCTTCTTC
CTGGTGTATTAGAGGCTTTA

Product: Nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSIPCIILAGGLGTRLRSALPDLPKCLAPVAGRPFLEWQMKSLFRRGIHHFVLALGYGADKIIEVLHQPWAKEMSIDYVI
EKEPLGTGGAIRFAMTDKLIDEVLVVNGDTFLNGDLSSLLEPLNRGSGEFMRMAAIHVSDRSRYGGVLVDQDKNVLAFIE
KGRHDSGLINAGVYHIHISVFEEYLMPSFSLEAEVMPILVKKGNLKFCEVSGPFVDIGVPSDYYSFQAQHKYYGIEC

Sequences:

>Translated_237_residues
MSIPCIILAGGLGTRLRSALPDLPKCLAPVAGRPFLEWQMKSLFRRGIHHFVLALGYGADKIIEVLHQPWAKEMSIDYVI
EKEPLGTGGAIRFAMTDKLIDEVLVVNGDTFLNGDLSSLLEPLNRGSGEFMRMAAIHVSDRSRYGGVLVDQDKNVLAFIE
KGRHDSGLINAGVYHIHISVFEEYLMPSFSLEAEVMPILVKKGNLKFCEVSGPFVDIGVPSDYYSFQAQHKYYGIEC
>Mature_236_residues
SIPCIILAGGLGTRLRSALPDLPKCLAPVAGRPFLEWQMKSLFRRGIHHFVLALGYGADKIIEVLHQPWAKEMSIDYVIE
KEPLGTGGAIRFAMTDKLIDEVLVVNGDTFLNGDLSSLLEPLNRGSGEFMRMAAIHVSDRSRYGGVLVDQDKNVLAFIEK
GRHDSGLINAGVYHIHISVFEEYLMPSFSLEAEVMPILVKKGNLKFCEVSGPFVDIGVPSDYYSFQAQHKYYGIEC

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=227, Percent_Identity=30.8370044052863, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI11761619, Length=227, Percent_Identity=30.8370044052863, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI133931050, Length=231, Percent_Identity=30.3030303030303, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17509979, Length=222, Percent_Identity=28.8288288288288, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=227, Percent_Identity=31.7180616740088, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355443, Length=225, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644084, Length=225, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 26304; Mature: 26173

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPCIILAGGLGTRLRSALPDLPKCLAPVAGRPFLEWQMKSLFRRGIHHFVLALGYGAD
CCCCEEEEECCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
KIIEVLHQPWAKEMSIDYVIEKEPLGTGGAIRFAMTDKLIDEVLVVNGDTFLNGDLSSLL
HHHHHHHCCCHHCCCEEEEEECCCCCCCCEEEEEEHHHHHHHEEEECCCEEECCCHHHHH
EPLNRGSGEFMRMAAIHVSDRSRYGGVLVDQDKNVLAFIEKGRHDSGLINAGVYHIHISV
HHHHCCCCCEEEEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCCEEECCEEEEEHHH
FEEYLMPSFSLEAEVMPILVKKGNLKFCEVSGPFVDIGVPSDYYSFQAQHKYYGIEC
HHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCEEEECCCCCHHHEEECCCEECCCC
>Mature Secondary Structure 
SIPCIILAGGLGTRLRSALPDLPKCLAPVAGRPFLEWQMKSLFRRGIHHFVLALGYGAD
CCCEEEEECCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
KIIEVLHQPWAKEMSIDYVIEKEPLGTGGAIRFAMTDKLIDEVLVVNGDTFLNGDLSSLL
HHHHHHHCCCHHCCCEEEEEECCCCCCCCEEEEEEHHHHHHHEEEECCCEEECCCHHHHH
EPLNRGSGEFMRMAAIHVSDRSRYGGVLVDQDKNVLAFIEKGRHDSGLINAGVYHIHISV
HHHHCCCCCEEEEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCCEEECCEEEEEHHH
FEEYLMPSFSLEAEVMPILVKKGNLKFCEVSGPFVDIGVPSDYYSFQAQHKYYGIEC
HHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCEEEECCCCCHHHEEECCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]