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The map label for this gene is corA [H]

Identifier: 194334422

GI number: 194334422

Start: 1758545

End: 1759609

Strand: Reverse

Name: corA [H]

Synonym: Paes_1617

Alternate gene names: 194334422

Gene position: 1759609-1758545 (Counterclockwise)

Preceding gene: 194334423

Following gene: 194334421

Centisome position: 70.02

GC content: 45.54

Gene sequence:

>1065_bases
ATGGCAAAGTTCAGTCGCAACTACTCTCGCAAGATCGGCCTTCCTGCAGGAAGTCTCATTCATCTGGGTGAAAAGAAACA
GGATGAAACCCGCATCAGTGTGATCGATTTCAATGAGGCTCATGTTGAGCGCCGGGAGGTCCGTCGAATCGAGGATTGTC
TGCCATACAAGCAGAGCGTTTCGACGACATGGATCAATATCGACGGTCTTGGCGAGGTTGATGTGATCGCCGATGCCGGG
AGGATTTTCGATATTAACGCTCTCGTTCTGGAAGATATTCTCCATACCGGACAACGTCCTAAAATCGAAGAGTATGAGAA
TATCGTCTTTTGTGTTCTTCGAATGATATCCTACGATGAAGAGCAGCAGAAGGTTTCAGAGGAGCAGTTGAGCCTGGTGC
TTGGCAAGGGTGTTCTTATCTCTTTTCAGGAAAAGCCGGGAGATATTTTCAACTCGCTTCGTGAGCGTCTTGTTCAGGGA
AAATCAAGGATTCGCACAAAAGGGGCTGATTATCTGGCATATGCGTTGATCGATATCGTTATCGATAATTATTTTGATGT
GCTTGACAAGGTTGAACTCAAGCTCGAACGTCTTGACGAAGAGCTTTTCAGCGATTCTTCCATCGAGACGTTCCGGGAGA
TCAGCGATCTGAAAAAAGAGCTGATCCAGCTTCGTAAATCCACCTGGCCTCTGCGCGAAATCGTTAATTCAATAACAAAA
AACGAGTTCAGCGTCATAGATGAGTCTAATCTCATCTATTTCAGAGATGTCTATGATCACACCATTCATGTGATCGATAT
TCTCGAAACCTTGCGTGACATGGTGGCGGCAATGCATGATACCTACATGAACTACGTCAATAATCGGATGAACGAGGTCA
TGAAGGTCCTGACGGTGATAGCAACAATTTTCATTCCCCTGACGTTTATAGCAGGAGTCTATGGTATGAATTTCCGCTAT
ATGCCCGAGCTGGAGTGGCGTTGGGGTTACTTCGGTGCGCTTGGCGTGATGGGACTCATTGTTGTTGGTATGGTGCTCTA
TTTCAAAAAGAAAAAATGGTTTTAA

Upstream 100 bases:

>100_bases
ACCCTGTTGCTTCTGGCGCTCGTTATTTCAGCAAGAACGATTTCCATATAGTTTTCGTCAGCATCTTCGTTGACTATCCA
GGTATTCAAACGGTCAGGTT

Downstream 100 bases:

>100_bases
CCAATCGCTGATTTTGAAACTTATGGGATGGATTAAAGTACTCGATAGTGCCCGGACGCTGCATGAGTCCGGAGTAATGG
AGGTGAATGCCGGCGGCAAG

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MAKFSRNYSRKIGLPAGSLIHLGEKKQDETRISVIDFNEAHVERREVRRIEDCLPYKQSVSTTWINIDGLGEVDVIADAG
RIFDINALVLEDILHTGQRPKIEEYENIVFCVLRMISYDEEQQKVSEEQLSLVLGKGVLISFQEKPGDIFNSLRERLVQG
KSRIRTKGADYLAYALIDIVIDNYFDVLDKVELKLERLDEELFSDSSIETFREISDLKKELIQLRKSTWPLREIVNSITK
NEFSVIDESNLIYFRDVYDHTIHVIDILETLRDMVAAMHDTYMNYVNNRMNEVMKVLTVIATIFIPLTFIAGVYGMNFRY
MPELEWRWGYFGALGVMGLIVVGMVLYFKKKKWF

Sequences:

>Translated_354_residues
MAKFSRNYSRKIGLPAGSLIHLGEKKQDETRISVIDFNEAHVERREVRRIEDCLPYKQSVSTTWINIDGLGEVDVIADAG
RIFDINALVLEDILHTGQRPKIEEYENIVFCVLRMISYDEEQQKVSEEQLSLVLGKGVLISFQEKPGDIFNSLRERLVQG
KSRIRTKGADYLAYALIDIVIDNYFDVLDKVELKLERLDEELFSDSSIETFREISDLKKELIQLRKSTWPLREIVNSITK
NEFSVIDESNLIYFRDVYDHTIHVIDILETLRDMVAAMHDTYMNYVNNRMNEVMKVLTVIATIFIPLTFIAGVYGMNFRY
MPELEWRWGYFGALGVMGLIVVGMVLYFKKKKWF
>Mature_353_residues
AKFSRNYSRKIGLPAGSLIHLGEKKQDETRISVIDFNEAHVERREVRRIEDCLPYKQSVSTTWINIDGLGEVDVIADAGR
IFDINALVLEDILHTGQRPKIEEYENIVFCVLRMISYDEEQQKVSEEQLSLVLGKGVLISFQEKPGDIFNSLRERLVQGK
SRIRTKGADYLAYALIDIVIDNYFDVLDKVELKLERLDEELFSDSSIETFREISDLKKELIQLRKSTWPLREIVNSITKN
EFSVIDESNLIYFRDVYDHTIHVIDILETLRDMVAAMHDTYMNYVNNRMNEVMKVLTVIATIFIPLTFIAGVYGMNFRYM
PELEWRWGYFGALGVMGLIVVGMVLYFKKKKWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=85, Percent_Identity=40, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41224; Mature: 41093

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFSRNYSRKIGLPAGSLIHLGEKKQDETRISVIDFNEAHVERREVRRIEDCLPYKQSV
CCCCCCCCHHCCCCCCCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHCC
STTWINIDGLGEVDVIADAGRIFDINALVLEDILHTGQRPKIEEYENIVFCVLRMISYDE
CEEEEEECCCCCCCEEECCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
EQQKVSEEQLSLVLGKGVLISFQEKPGDIFNSLRERLVQGKSRIRTKGADYLAYALIDIV
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IDNYFDVLDKVELKLERLDEELFSDSSIETFREISDLKKELIQLRKSTWPLREIVNSITK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
NEFSVIDESNLIYFRDVYDHTIHVIDILETLRDMVAAMHDTYMNYVNNRMNEVMKVLTVI
CHHHEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATIFIPLTFIAGVYGMNFRYMPELEWRWGYFGALGVMGLIVVGMVLYFKKKKWF
HHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKFSRNYSRKIGLPAGSLIHLGEKKQDETRISVIDFNEAHVERREVRRIEDCLPYKQSV
CCCCCCCHHCCCCCCCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHCC
STTWINIDGLGEVDVIADAGRIFDINALVLEDILHTGQRPKIEEYENIVFCVLRMISYDE
CEEEEEECCCCCCCEEECCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
EQQKVSEEQLSLVLGKGVLISFQEKPGDIFNSLRERLVQGKSRIRTKGADYLAYALIDIV
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IDNYFDVLDKVELKLERLDEELFSDSSIETFREISDLKKELIQLRKSTWPLREIVNSITK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
NEFSVIDESNLIYFRDVYDHTIHVIDILETLRDMVAAMHDTYMNYVNNRMNEVMKVLTVI
CHHHEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATIFIPLTFIAGVYGMNFRYMPELEWRWGYFGALGVMGLIVVGMVLYFKKKKWF
HHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]