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The map label for this gene is trxB [H]

Identifier: 194334338

GI number: 194334338

Start: 1671197

End: 1672138

Strand: Reverse

Name: trxB [H]

Synonym: Paes_1531

Alternate gene names: 194334338

Gene position: 1672138-1671197 (Counterclockwise)

Preceding gene: 194334343

Following gene: 194334336

Centisome position: 66.54

GC content: 52.12

Gene sequence:

>942_bases
ATGGAGACTCTACATTGTGATGTAGCCATCATAGGCGGAGGCCCTGCGGGCTGTTCTGCGGCGATATATACGGCGAGGGC
TGATCTGGATACGGTTATTATCGACAAGGATCCGCATGCGGGGGCTCTTGGTATGGCCCATATTATCGCGAATTACCCCG
GAATGGGTAACGACATAACCGGTATGGAACTTCTGGAGAGCATGCGGCGCCATGCCGGTTCATTTGGTGCGCGTTTCATG
AAGCAGAAGGTGAATGGAATCGATGTCAGAAATCCTGAAAAAACCGTCTTTACCACCTCAGGAACAATGTTCAAGGCAAA
AGCATTGATTCTCGCGACCGGTTCCATGGGTAAAAGCCGCGAACTTCCCGGTGAAAAAGAGTTGCTTGGCGCAGGGGTGA
GTTATTGTGCGACCTGTGATGCCGCGTTTTATCGACAGAAAGTTGTCGCTGTTGCCGGCAGGACCCGTGAGGCTGTCGAA
GAGGCTCTTGTGCTATCGCGTTTTGCGTCAAAAGTGTATCTCTTCTGCCCGACGGCGTCTTTGACAGCTCCACCTGAGGA
TATCCATATGCTTCAGGAGCAGAAGAATATCGAGGTGTTTTACAGCAGGCGGCTTGATGCAATCAACGGCGGGAAGTTCG
TTGAATCTGTGACGCTTGGGGCACCTGAAGAGGTTGTTGCGGTTGACGGTGTATTCCTCTATCTGACAGGATCGGCTCCG
GTACTGGATTTTACCGGAGGGCAGTTGGATGTTTGTCAGAGCGGCTGCTTGCAGGTCGATAAGGATTTTATGACCTCTGT
TCCCGGTGTTTTCGCCGCAGGTGATATTTTGTGCAAGGAGGTTAAACAGGCCGTCATCGTGGCTTCAGAAGGGTGTCGCG
CAGCATTGCAGGTCGATAAATTTCTTCGTGGCCGCGACAGGGCAAGAAGTGACTACCAGTGA

Upstream 100 bases:

>100_bases
TAAGTGTATGAATGACCCGACATATCAAATTATCTGCCCTGCCGGTAATAGTCAAGGATAAAATTGTTGAAATGACTTTG
TAATTTAAATTGATGTTTTC

Downstream 100 bases:

>100_bases
TTGCTGTCAGCAGAAGAGGTTGCTGAAATTTCTGACTCCCGCAGGAGATGAAAGAAGAAACCCTTCACCATACAATGTGC
CGATCTGTTCTCCGAGGTAG

Product: Thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
METLHCDVAIIGGGPAGCSAAIYTARADLDTVIIDKDPHAGALGMAHIIANYPGMGNDITGMELLESMRRHAGSFGARFM
KQKVNGIDVRNPEKTVFTTSGTMFKAKALILATGSMGKSRELPGEKELLGAGVSYCATCDAAFYRQKVVAVAGRTREAVE
EALVLSRFASKVYLFCPTASLTAPPEDIHMLQEQKNIEVFYSRRLDAINGGKFVESVTLGAPEEVVAVDGVFLYLTGSAP
VLDFTGGQLDVCQSGCLQVDKDFMTSVPGVFAAGDILCKEVKQAVIVASEGCRAALQVDKFLRGRDRARSDYQ

Sequences:

>Translated_313_residues
METLHCDVAIIGGGPAGCSAAIYTARADLDTVIIDKDPHAGALGMAHIIANYPGMGNDITGMELLESMRRHAGSFGARFM
KQKVNGIDVRNPEKTVFTTSGTMFKAKALILATGSMGKSRELPGEKELLGAGVSYCATCDAAFYRQKVVAVAGRTREAVE
EALVLSRFASKVYLFCPTASLTAPPEDIHMLQEQKNIEVFYSRRLDAINGGKFVESVTLGAPEEVVAVDGVFLYLTGSAP
VLDFTGGQLDVCQSGCLQVDKDFMTSVPGVFAAGDILCKEVKQAVIVASEGCRAALQVDKFLRGRDRARSDYQ
>Mature_313_residues
METLHCDVAIIGGGPAGCSAAIYTARADLDTVIIDKDPHAGALGMAHIIANYPGMGNDITGMELLESMRRHAGSFGARFM
KQKVNGIDVRNPEKTVFTTSGTMFKAKALILATGSMGKSRELPGEKELLGAGVSYCATCDAAFYRQKVVAVAGRTREAVE
EALVLSRFASKVYLFCPTASLTAPPEDIHMLQEQKNIEVFYSRRLDAINGGKFVESVTLGAPEEVVAVDGVFLYLTGSAP
VLDFTGGQLDVCQSGCLQVDKDFMTSVPGVFAAGDILCKEVKQAVIVASEGCRAALQVDKFLRGRDRARSDYQ

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=36.7088607594937, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87081763, Length=214, Percent_Identity=30.3738317757009, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321898, Length=319, Percent_Identity=33.8557993730408, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=34.2857142857143, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33461; Mature: 33461

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLHCDVAIIGGGPAGCSAAIYTARADLDTVIIDKDPHAGALGMAHIIANYPGMGNDIT
CCCEEEEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCC
GMELLESMRRHAGSFGARFMKQKVNGIDVRNPEKTVFTTSGTMFKAKALILATGSMGKSR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCCCC
ELPGEKELLGAGVSYCATCDAAFYRQKVVAVAGRTREAVEEALVLSRFASKVYLFCPTAS
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEECCCC
LTAPPEDIHMLQEQKNIEVFYSRRLDAINGGKFVESVTLGAPEEVVAVDGVFLYLTGSAP
CCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEECCEEEEEECCCC
VLDFTGGQLDVCQSGCLQVDKDFMTSVPGVFAAGDILCKEVKQAVIVASEGCRAALQVDK
EEEECCCCHHHHHHCHHHCCHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHH
FLRGRDRARSDYQ
HHHHHHCCCCCCC
>Mature Secondary Structure
METLHCDVAIIGGGPAGCSAAIYTARADLDTVIIDKDPHAGALGMAHIIANYPGMGNDIT
CCCEEEEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCC
GMELLESMRRHAGSFGARFMKQKVNGIDVRNPEKTVFTTSGTMFKAKALILATGSMGKSR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCCCC
ELPGEKELLGAGVSYCATCDAAFYRQKVVAVAGRTREAVEEALVLSRFASKVYLFCPTAS
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEECCCC
LTAPPEDIHMLQEQKNIEVFYSRRLDAINGGKFVESVTLGAPEEVVAVDGVFLYLTGSAP
CCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEECCEEEEEECCCC
VLDFTGGQLDVCQSGCLQVDKDFMTSVPGVFAAGDILCKEVKQAVIVASEGCRAALQVDK
EEEECCCCHHHHHHCHHHCCHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHH
FLRGRDRARSDYQ
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]