Click here to switch to the map view.

The map label for this gene is lrp [C]

Identifier: 194334329

GI number: 194334329

Start: 1663405

End: 1663929

Strand: Reverse

Name: lrp [C]

Synonym: Paes_1522

Alternate gene names: 194334329

Gene position: 1663929-1663405 (Counterclockwise)

Preceding gene: 194334336

Following gene: 194334328

Centisome position: 66.21

GC content: 44.76

Gene sequence:

>525_bases
ATGTCTGGAAATCTGGACCTTATCGACTTGAAAATAGTGGAGACCATGGGGGATAACGCCCGCATTCGGTTGAGCGAGCT
TGCCGAAATTGTTGGTTTATCCATTCCGTCAGTCAGTGAACGTCTCGACAAGCTTCAGAAAAAGGGGATTATTCAAAAGT
TCACGACGGTTGTCGATGAACGGCAGCTGGGCTTCGATATTCAGGCTTTTGTTCGCGTGAGGATTGATTCCTCAAAGCAC
TATAAATCCTTTATGGAGCACGTGCTTCGTGAGGAGGAAATTATGGAGTGTTATTCTGTTACCGGAGACGGTTCTCATAT
ACTCAAGGTTATGACCCACAATACGGCTTCACTTGAACAGTTTTTATCCAGAATTCAGAGCTGGCCGGGAATATTGGGGA
CTAATACAAGTTTTGTGTTGTCAGAAATCAAGAGAAATACCCGTCTGAGTTCTGAGATTGTCAAGAAAAACCTGCTCGAC
CGGCAGGTGCTTATCAGTTTTGACGAAAAGAAGTCCCGGAAATAG

Upstream 100 bases:

>100_bases
AAGGCCTGAGTTGTTCAGGTGATGGTTTTTTTGGAAAAAGCTTGTGTCAGTCTTATTTTTTTTGTAATCTTGAGTGGTAA
AAATACAAAATTGTAGGTTT

Downstream 100 bases:

>100_bases
GTTTTGTATTTATTACTGTGATTCGTTTCATGAAAAATCATAAGGAGGATAACCTTTGGAAAATGTTAACAAAAAAGCGG
TATCATCGTATTTTGGCGCT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSGNLDLIDLKIVETMGDNARIRLSELAEIVGLSIPSVSERLDKLQKKGIIQKFTTVVDERQLGFDIQAFVRVRIDSSKH
YKSFMEHVLREEEIMECYSVTGDGSHILKVMTHNTASLEQFLSRIQSWPGILGTNTSFVLSEIKRNTRLSSEIVKKNLLD
RQVLISFDEKKSRK

Sequences:

>Translated_174_residues
MSGNLDLIDLKIVETMGDNARIRLSELAEIVGLSIPSVSERLDKLQKKGIIQKFTTVVDERQLGFDIQAFVRVRIDSSKH
YKSFMEHVLREEEIMECYSVTGDGSHILKVMTHNTASLEQFLSRIQSWPGILGTNTSFVLSEIKRNTRLSSEIVKKNLLD
RQVLISFDEKKSRK
>Mature_173_residues
SGNLDLIDLKIVETMGDNARIRLSELAEIVGLSIPSVSERLDKLQKKGIIQKFTTVVDERQLGFDIQAFVRVRIDSSKHY
KSFMEHVLREEEIMECYSVTGDGSHILKVMTHNTASLEQFLSRIQSWPGILGTNTSFVLSEIKRNTRLSSEIVKKNLLDR
QVLISFDEKKSRK

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=30.2013422818792, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790182, Length=137, Percent_Identity=32.8467153284672, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=27.1523178807947, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR001845
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 19883; Mature: 19752

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNLDLIDLKIVETMGDNARIRLSELAEIVGLSIPSVSERLDKLQKKGIIQKFTTVVDE
CCCCCEEEEHHEEECCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQLGFDIQAFVRVRIDSSKHYKSFMEHVLREEEIMECYSVTGDGSHILKVMTHNTASLEQ
HHCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHH
FLSRIQSWPGILGTNTSFVLSEIKRNTRLSSEIVKKNLLDRQVLISFDEKKSRK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCC
>Mature Secondary Structure 
SGNLDLIDLKIVETMGDNARIRLSELAEIVGLSIPSVSERLDKLQKKGIIQKFTTVVDE
CCCCEEEEHHEEECCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQLGFDIQAFVRVRIDSSKHYKSFMEHVLREEEIMECYSVTGDGSHILKVMTHNTASLEQ
HHCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHH
FLSRIQSWPGILGTNTSFVLSEIKRNTRLSSEIVKKNLLDRQVLISFDEKKSRK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]