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The map label for this gene is btuC [H]

Identifier: 194334110

GI number: 194334110

Start: 1417600

End: 1418688

Strand: Reverse

Name: btuC [H]

Synonym: Paes_1298

Alternate gene names: 194334110

Gene position: 1418688-1417600 (Counterclockwise)

Preceding gene: 194334111

Following gene: 194334109

Centisome position: 56.46

GC content: 57.21

Gene sequence:

>1089_bases
ATGAGTGTTGATGATACCGCTTCCGGGGGCGCGCATCCCTGGCCCCGGCTTACCTTGCGGCTTCCTCTCGTGATGCTGCT
TCTGGCACTGGTGCTTTTCTTTTTTCTGCTGGACCTCGTGCTTGGCTCGGTGAGGATCCCTTTACCGAGTGTGGTCTCTA
TTCTTATGGGCAACGGCTCGGATATCGAGGCCTGGGACAAGATCGTTACCTATATCAGATTGCCGAAAGCCCTGACCGCC
GTGCTGGCGGGGGCAGCTCTTTCGGTGAGTGGGCTGCAGATGCAGACACTGTTCCGCAACCCGCTTGCAGGTCCTTCGGT
ACTCGGTATTTCAGCCGGCGCCAGTCTCGGGGTGGCGATGGTGATGCTTGCCTCCGGTTCCGCAGCCAATGCGTTTGCCA
TCCGACAGCTCGGGCTCGGGGGGAGCTGGCTGATTGTGATCTCCGCTACGCTCGGTGCGGCTTGCGTGCTGCTGGTCGTT
CTGGCAATAGCGGTCAGGATCAAGGATAATATCGTGCTTCTGATCGTAGGTATCATGGTAGGAAACATGACGGTTTCCCT
TATCAGTATATGGCAGTATTTCAGCGAACCGGAAGAGATACAGGACTACCTTATCTGGACCTTCGGCAGCCTCGGGGGGG
TGCTTGGCAATCAGCTCTGGGTGCTCGCGGCGGTCATCGGTATCGGTCTCCTGGTCTCTTTTGCGGCATCGAAGTCCCTC
AATGTCATGCTGCTCGGTGAGAATTATGCCCGAAGCCTCGGCATGAGCACGTTTTACGTCAGGGTGACGGTCATCGCGGC
AACCAGCCTGCTTGCCGGGAGCGTGACCGGTTTCTGCGGTCCGATCGGTTTCATCGGTATTGCCGTGCCGCACCTGACAC
GCTCGATACTCGATACCTCGGATCACCGTTTCCTGATGCCGGGTGTCTGCCTGATGGGGGCCCTTGTGATGCTGGTGTGT
GACATTATCGCCCAGATGCCGGGAAGCCAGACGACGCTGCCGATCAACGCCGTTACGGCGCTTATCGGTTCGCCTGTAGT
GATCTGGGTTATTATGAAAAACAGAAACCTGAAGTCTTCATTCTCATGA

Upstream 100 bases:

>100_bases
CGGATTCTCAAGGACCTGATCATGATCCTGCACCCTGACATTGCGGAGCGTGAAGGGTTTCAGGATGATTCTCTAACGTT
TTACCATCTTATCGATTGAC

Downstream 100 bases:

>100_bases
ACAGTGTTCTATTGCAGACCCGGGATCTTGAAATCGGCTACAAGATTCGCCGGCCCGCTTCGGCTGCAGCCACGCATGGC
CACAGGTACATGGCCAGGGT

Product: transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSVDDTASGGAHPWPRLTLRLPLVMLLLALVLFFFLLDLVLGSVRIPLPSVVSILMGNGSDIEAWDKIVTYIRLPKALTA
VLAGAALSVSGLQMQTLFRNPLAGPSVLGISAGASLGVAMVMLASGSAANAFAIRQLGLGGSWLIVISATLGAACVLLVV
LAIAVRIKDNIVLLIVGIMVGNMTVSLISIWQYFSEPEEIQDYLIWTFGSLGGVLGNQLWVLAAVIGIGLLVSFAASKSL
NVMLLGENYARSLGMSTFYVRVTVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILDTSDHRFLMPGVCLMGALVMLVC
DIIAQMPGSQTTLPINAVTALIGSPVVIWVIMKNRNLKSSFS

Sequences:

>Translated_362_residues
MSVDDTASGGAHPWPRLTLRLPLVMLLLALVLFFFLLDLVLGSVRIPLPSVVSILMGNGSDIEAWDKIVTYIRLPKALTA
VLAGAALSVSGLQMQTLFRNPLAGPSVLGISAGASLGVAMVMLASGSAANAFAIRQLGLGGSWLIVISATLGAACVLLVV
LAIAVRIKDNIVLLIVGIMVGNMTVSLISIWQYFSEPEEIQDYLIWTFGSLGGVLGNQLWVLAAVIGIGLLVSFAASKSL
NVMLLGENYARSLGMSTFYVRVTVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILDTSDHRFLMPGVCLMGALVMLVC
DIIAQMPGSQTTLPINAVTALIGSPVVIWVIMKNRNLKSSFS
>Mature_361_residues
SVDDTASGGAHPWPRLTLRLPLVMLLLALVLFFFLLDLVLGSVRIPLPSVVSILMGNGSDIEAWDKIVTYIRLPKALTAV
LAGAALSVSGLQMQTLFRNPLAGPSVLGISAGASLGVAMVMLASGSAANAFAIRQLGLGGSWLIVISATLGAACVLLVVL
AIAVRIKDNIVLLIVGIMVGNMTVSLISIWQYFSEPEEIQDYLIWTFGSLGGVLGNQLWVLAAVIGIGLLVSFAASKSLN
VMLLGENYARSLGMSTFYVRVTVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILDTSDHRFLMPGVCLMGALVMLVCD
IIAQMPGSQTTLPINAVTALIGSPVVIWVIMKNRNLKSSFS

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=37.3702422145329, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790741, Length=292, Percent_Identity=31.1643835616438, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790740, Length=320, Percent_Identity=29.6875, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786347, Length=289, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=30.9904153354633, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786804, Length=260, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37992; Mature: 37861

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDDTASGGAHPWPRLTLRLPLVMLLLALVLFFFLLDLVLGSVRIPLPSVVSILMGNGS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
DIEAWDKIVTYIRLPKALTAVLAGAALSVSGLQMQTLFRNPLAGPSVLGISAGASLGVAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCHHHHHHH
VMLASGSAANAFAIRQLGLGGSWLIVISATLGAACVLLVVLAIAVRIKDNIVLLIVGIMV
HHHHCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GNMTVSLISIWQYFSEPEEIQDYLIWTFGSLGGVLGNQLWVLAAVIGIGLLVSFAASKSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVMLLGENYARSLGMSTFYVRVTVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILDTS
EEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHRFLMPGVCLMGALVMLVCDIIAQMPGSQTTLPINAVTALIGSPVVIWVIMKNRNLKSS
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCC
FS
CC
>Mature Secondary Structure 
SVDDTASGGAHPWPRLTLRLPLVMLLLALVLFFFLLDLVLGSVRIPLPSVVSILMGNGS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
DIEAWDKIVTYIRLPKALTAVLAGAALSVSGLQMQTLFRNPLAGPSVLGISAGASLGVAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCHHHHHHH
VMLASGSAANAFAIRQLGLGGSWLIVISATLGAACVLLVVLAIAVRIKDNIVLLIVGIMV
HHHHCCCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GNMTVSLISIWQYFSEPEEIQDYLIWTFGSLGGVLGNQLWVLAAVIGIGLLVSFAASKSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVMLLGENYARSLGMSTFYVRVTVIAATSLLAGSVTGFCGPIGFIGIAVPHLTRSILDTS
EEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DHRFLMPGVCLMGALVMLVCDIIAQMPGSQTTLPINAVTALIGSPVVIWVIMKNRNLKSS
CCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCC
FS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA