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The map label for this gene is 194334106

Identifier: 194334106

GI number: 194334106

Start: 1412688

End: 1414190

Strand: Reverse

Name: 194334106

Synonym: Paes_1294

Alternate gene names: NA

Gene position: 1414190-1412688 (Counterclockwise)

Preceding gene: 194334107

Following gene: 194334105

Centisome position: 56.28

GC content: 58.55

Gene sequence:

>1503_bases
ATGGAAAGAGTGACAATCGCACTGGTTCATGCCGATATCCGGCATCGTGATGTTGCGGCAAACCGTCGCGAACTTCTGAA
CCTCAACCGTGAGGCGGCAGGAAACGGGGCGGATATTATCGTGAATACCGAGCTGGGGCTCACCGGCTACAGCTTCCGTT
CACGGGAGGATATCGCTCCGCTGGTCGAAGAGTATGACGGCCCTGTGGTGCAGGAGCTCTCGCTGATCGCTTCCCGCTAT
GGATGTTATATCGTCTTCGGCTATGCCGAAAAAGACGCAGGGACGGATATTTACTACAATGCAGCGGCTGTGATCGGTCC
TGACGGCAGGCTCTTGTTGAATTACCGTAAGGTGACAGCCGAGGTGCGCTGGGCATGTGCAGGAAGTCCCGGCCAGCCCA
ATACCTTCGATACACCCTGGGGCCGGATCGCTGTCGTGATCTGCTCCGATACCTATTACGGGTCTCTTGCCCGGATGTCG
GCGCTCAGGGGGGCCGATCTTCTGCTTGTTCCTGCTAACTGGCCGGCGGGGTCGCTGGACCCGAGGGAACTGTGGCAGGT
GCGTGCGCGGGAAAACGGGGTGTACCTTGCCGCCTGCAATCGTGGAGGTCACGACAGGACCATGTCGTGCGAGGATGCAT
GGAGCTCTGTGTACTCGCCCGATGGCGAGGAACTCTTCGCGGCAAGCAGCTGTAACTCCAGGGTTTTTTCCGTGCAAATC
CCCCTTGAAAATGGAATGATCCCGTCGAAAAGAGCCCGGCGGCTGGCATCGAGGACTCCCGCGAGGTATGCGCCGATCTA
CCTGGATATGCGCTACGCAACGGATATGACCTCCTACTGCAACCTGCCCGAGCCTGGCCCCCTGACTGTCACCTGCCTGC
CAGCCGATCCGCACGATCTTTTTATACAAGGCAGGCTCGATATGCTGCTTGACGAGCAGGCCGGACAGCGCCCTGATCTC
CTGGTCCTGCCTGCCGGTGAGACGGCAGACAGGGAGCGGACGGCAGGGCTCGTCAGCGGCATGGCATCACGTTTGAGGGT
GGCTGTATGCACCGCAATCCCTGGCCCGGAAGGATTCAGCATGCTCTGCGCGGAGGCCAGCGGCCAGCTGCATGTCGTCA
GGGAGGGGTGTCCGGAAAGCGTGATGATTGACCTCGACAAAGCGCGCATTGCTCTTGCAGGCAGGGAGGAGCTCTATCAT
CCTGAATATGTGACAGCCCTTGCCAAGCAGGGGTGTGATCTGGTCGTGTGTTCCACTCGCTCCTGTAATGCCCTCGATCG
CAGTGTCCTCGGTTCGAGGTCGATAGAGCAGGTGGCGGTAGCGGTCTGCTCTCCTGACAACGCCTTTATCTGCAAACCTC
CCATCGGTCACTACCGTTGGGAAGAGGTTTACACGGTATCCGCAAGTCATCCCTGTACAGCCGAGCTCGATATCTCCCTG
CTGCGCAACAAGCATTTTTATGACAGGCTGGAGTTCGATCTCCTCCTTGGAAAACAGAATTAA

Upstream 100 bases:

>100_bases
GCCGTTATGCCGGCCAGCTCGAGCATGAAGCCGCGGGAACAGGTAACGACGAATTTCTTAAATTTCTTTTTGCGTGCTGC
GCGCTGGGGTACAGTGAAAA

Downstream 100 bases:

>100_bases
GAACGATGTATCATGTCTGAAACACACAACGGGGGACGGGTGGTGATTGCCGGTGCAGGCCCGGGAGATCCGGAGTTGCT
GACCGTGAAGGCCGCCAGAC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MERVTIALVHADIRHRDVAANRRELLNLNREAAGNGADIIVNTELGLTGYSFRSREDIAPLVEEYDGPVVQELSLIASRY
GCYIVFGYAEKDAGTDIYYNAAAVIGPDGRLLLNYRKVTAEVRWACAGSPGQPNTFDTPWGRIAVVICSDTYYGSLARMS
ALRGADLLLVPANWPAGSLDPRELWQVRARENGVYLAACNRGGHDRTMSCEDAWSSVYSPDGEELFAASSCNSRVFSVQI
PLENGMIPSKRARRLASRTPARYAPIYLDMRYATDMTSYCNLPEPGPLTVTCLPADPHDLFIQGRLDMLLDEQAGQRPDL
LVLPAGETADRERTAGLVSGMASRLRVAVCTAIPGPEGFSMLCAEASGQLHVVREGCPESVMIDLDKARIALAGREELYH
PEYVTALAKQGCDLVVCSTRSCNALDRSVLGSRSIEQVAVAVCSPDNAFICKPPIGHYRWEEVYTVSASHPCTAELDISL
LRNKHFYDRLEFDLLLGKQN

Sequences:

>Translated_500_residues
MERVTIALVHADIRHRDVAANRRELLNLNREAAGNGADIIVNTELGLTGYSFRSREDIAPLVEEYDGPVVQELSLIASRY
GCYIVFGYAEKDAGTDIYYNAAAVIGPDGRLLLNYRKVTAEVRWACAGSPGQPNTFDTPWGRIAVVICSDTYYGSLARMS
ALRGADLLLVPANWPAGSLDPRELWQVRARENGVYLAACNRGGHDRTMSCEDAWSSVYSPDGEELFAASSCNSRVFSVQI
PLENGMIPSKRARRLASRTPARYAPIYLDMRYATDMTSYCNLPEPGPLTVTCLPADPHDLFIQGRLDMLLDEQAGQRPDL
LVLPAGETADRERTAGLVSGMASRLRVAVCTAIPGPEGFSMLCAEASGQLHVVREGCPESVMIDLDKARIALAGREELYH
PEYVTALAKQGCDLVVCSTRSCNALDRSVLGSRSIEQVAVAVCSPDNAFICKPPIGHYRWEEVYTVSASHPCTAELDISL
LRNKHFYDRLEFDLLLGKQN
>Mature_500_residues
MERVTIALVHADIRHRDVAANRRELLNLNREAAGNGADIIVNTELGLTGYSFRSREDIAPLVEEYDGPVVQELSLIASRY
GCYIVFGYAEKDAGTDIYYNAAAVIGPDGRLLLNYRKVTAEVRWACAGSPGQPNTFDTPWGRIAVVICSDTYYGSLARMS
ALRGADLLLVPANWPAGSLDPRELWQVRARENGVYLAACNRGGHDRTMSCEDAWSSVYSPDGEELFAASSCNSRVFSVQI
PLENGMIPSKRARRLASRTPARYAPIYLDMRYATDMTSYCNLPEPGPLTVTCLPADPHDLFIQGRLDMLLDEQAGQRPDL
LVLPAGETADRERTAGLVSGMASRLRVAVCTAIPGPEGFSMLCAEASGQLHVVREGCPESVMIDLDKARIALAGREELYH
PEYVTALAKQGCDLVVCSTRSCNALDRSVLGSRSIEQVAVAVCSPDNAFICKPPIGHYRWEEVYTVSASHPCTAELDISL
LRNKHFYDRLEFDLLLGKQN

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=250, Percent_Identity=31.6, Blast_Score=88, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322522, Length=119, Percent_Identity=36.9747899159664, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: NA

Molecular weight: Translated: 54888; Mature: 54888

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVTIALVHADIRHRDVAANRRELLNLNREAAGNGADIIVNTELGLTGYSFRSREDIAP
CCEEEEEEEECCCHHHHHHHCHHHHHCCCHHCCCCCCEEEEEECCCCCCCCCCCCCHHHH
LVEEYDGPVVQELSLIASRYGCYIVFGYAEKDAGTDIYYNAAAVIGPDGRLLLNYRKVTA
HHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEEEEECCCCEEEEEEEEEEE
EVRWACAGSPGQPNTFDTPWGRIAVVICSDTYYGSLARMSALRGADLLLVPANWPAGSLD
EEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCC
PRELWQVRARENGVYLAACNRGGHDRTMSCEDAWSSVYSPDGEELFAASSCNSRVFSVQI
HHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEEE
PLENGMIPSKRARRLASRTPARYAPIYLDMRYATDMTSYCNLPEPGPLTVTCLPADPHDL
ECCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHCCHHHHCCCCCCCCEEEEEECCCCCEE
FIQGRLDMLLDEQAGQRPDLLVLPAGETADRERTAGLVSGMASRLRVAVCTAIPGPEGFS
EEECCHHEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCE
MLCAEASGQLHVVREGCPESVMIDLDKARIALAGREELYHPEYVTALAKQGCDLVVCSTR
EEEECCCCCEEEEECCCCCCEEEEECCCEEEEECCHHCCCHHHHHHHHHCCCCEEEECCC
SCNALDRSVLGSRSIEQVAVAVCSPDNAFICKPPIGHYRWEEVYTVSASHPCTAELDISL
CCCHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCEEEEHHH
LRNKHFYDRLEFDLLLGKQN
HHCCCHHHHEEEEEEEECCC
>Mature Secondary Structure
MERVTIALVHADIRHRDVAANRRELLNLNREAAGNGADIIVNTELGLTGYSFRSREDIAP
CCEEEEEEEECCCHHHHHHHCHHHHHCCCHHCCCCCCEEEEEECCCCCCCCCCCCCHHHH
LVEEYDGPVVQELSLIASRYGCYIVFGYAEKDAGTDIYYNAAAVIGPDGRLLLNYRKVTA
HHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEEEEECCCCEEEEEEEEEEE
EVRWACAGSPGQPNTFDTPWGRIAVVICSDTYYGSLARMSALRGADLLLVPANWPAGSLD
EEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCC
PRELWQVRARENGVYLAACNRGGHDRTMSCEDAWSSVYSPDGEELFAASSCNSRVFSVQI
HHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEEE
PLENGMIPSKRARRLASRTPARYAPIYLDMRYATDMTSYCNLPEPGPLTVTCLPADPHDL
ECCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHCCHHHHCCCCCCCCEEEEEECCCCCEE
FIQGRLDMLLDEQAGQRPDLLVLPAGETADRERTAGLVSGMASRLRVAVCTAIPGPEGFS
EEECCHHEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCE
MLCAEASGQLHVVREGCPESVMIDLDKARIALAGREELYHPEYVTALAKQGCDLVVCSTR
EEEECCCCCEEEEECCCCCCEEEEECCCEEEEECCHHCCCHHHHHHHHHCCCCEEEECCC
SCNALDRSVLGSRSIEQVAVAVCSPDNAFICKPPIGHYRWEEVYTVSASHPCTAELDISL
CCCHHHHHHHCCCCCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCEEEEHHH
LRNKHFYDRLEFDLLLGKQN
HHCCCHHHHEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]