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The map label for this gene is cobT

Identifier: 194334067

GI number: 194334067

Start: 1356554

End: 1357615

Strand: Reverse

Name: cobT

Synonym: Paes_1254

Alternate gene names: 194334067

Gene position: 1357615-1356554 (Counterclockwise)

Preceding gene: 194334068

Following gene: 194334066

Centisome position: 54.03

GC content: 51.98

Gene sequence:

>1062_bases
ATGATAGAGCAGTTTCAGCAGGTTCTTGCTTCGGTGAAATCTGTAGATATGTCATTGACAAAAGAGGTGCAGGCTCATCT
TGATGATCTTACAAAGCCCCGTGGCAGTCTGGGCCGTCTGGAGGAGATTGCAATGAAGTACGTTCTTGCAACAGGAAGCC
TGCGGCCGGAGCTGAGAAAGAAAAAGGTTTTTTGCTTTGCGGCGGATCATGGTGTGGCCGTAGAGGGTGTATCGGCGTTT
CCGGCTGAAGTGACTCCGCAGATGGTCTATAATATGCTTGCCGGCGGTGCGGCGATCAATGTGCTCTCACGCCATGCCGG
TGCGGATCTCGATGTGGTTGATATGGGCGTTCATCATGATTTCGTCGAGCATCCTTCTTTGCGCATATGCAAAGTGCGTC
ATGGGTCGTCCAACATGGCAGAAGGCCCTGCGATGACAATGGATGAAACGCTGCAGGCCATCATGACTGGCGTCAGTCTT
GCACATGAAGCCCGCAAGGAGGGCTATGACCTTCTGGCTACCGGTGAAATGGGTATTGCCAATACGACTCCGGCTACGGC
ACTGTATGCTTCGATGCTTGACCTTCCTGTTGAAATGATCACCGGGCGCGGGACTGGAATTGACGATGCTGTTCTGCAAC
ACAAGATCAGCGTTATTAAGAGGGCTCTGGATGTCAACAGTGCTTCGCTTTCTACTCCGCTTGAACAACTGGCTGCTTTG
GGTGGTTTTGAAATCGCCGGTATCTGTGGCCTTATTCTTGGGGCTGCTTCGGTGGGAATGCCTGTTGTTGTCGACGGCTT
TATTTCTTCTGCCGGCGCTGTTGCTGCTCTCAAGCTTTCATGCAGGGTAAGTGATTATCTTTTCTTCAGTCACTTATCCA
ATGAGCAGGGCCATAAGGCCATCATGAACCGCCTCGGGGCAAGACCGATCCTGGATCTTGATCTTCGCCTGGGAGAGGGG
ACAGGAGCTGCGCTTGCCATGCAGGTTGTCGAGGCTTCTGTAAAACTGTACAATGAAATGGCGACGTTCAGTTCCGCCAG
TGTTTCGGGAAAATCAGTGTGA

Upstream 100 bases:

>100_bases
TAACGATTAACGATTAACGATTAACGATTAACGATTAACGATTAACGATTAACGATTAACGATTAACGATTAACGATTAA
CGATTAACGATTAACGACCC

Downstream 100 bases:

>100_bases
TTACACGTGTGCAATGAGAGAAGAATCTTTTGATCAGTCAGTACGGCGGCTCAAGGATGACGACAGCCGTTTTGTTGCCT
GCAACGGTTTTGATGTCCAT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIEQFQQVLASVKSVDMSLTKEVQAHLDDLTKPRGSLGRLEEIAMKYVLATGSLRPELRKKKVFCFAADHGVAVEGVSAF
PAEVTPQMVYNMLAGGAAINVLSRHAGADLDVVDMGVHHDFVEHPSLRICKVRHGSSNMAEGPAMTMDETLQAIMTGVSL
AHEARKEGYDLLATGEMGIANTTPATALYASMLDLPVEMITGRGTGIDDAVLQHKISVIKRALDVNSASLSTPLEQLAAL
GGFEIAGICGLILGAASVGMPVVVDGFISSAGAVAALKLSCRVSDYLFFSHLSNEQGHKAIMNRLGARPILDLDLRLGEG
TGAALAMQVVEASVKLYNEMATFSSASVSGKSV

Sequences:

>Translated_353_residues
MIEQFQQVLASVKSVDMSLTKEVQAHLDDLTKPRGSLGRLEEIAMKYVLATGSLRPELRKKKVFCFAADHGVAVEGVSAF
PAEVTPQMVYNMLAGGAAINVLSRHAGADLDVVDMGVHHDFVEHPSLRICKVRHGSSNMAEGPAMTMDETLQAIMTGVSL
AHEARKEGYDLLATGEMGIANTTPATALYASMLDLPVEMITGRGTGIDDAVLQHKISVIKRALDVNSASLSTPLEQLAAL
GGFEIAGICGLILGAASVGMPVVVDGFISSAGAVAALKLSCRVSDYLFFSHLSNEQGHKAIMNRLGARPILDLDLRLGEG
TGAALAMQVVEASVKLYNEMATFSSASVSGKSV
>Mature_353_residues
MIEQFQQVLASVKSVDMSLTKEVQAHLDDLTKPRGSLGRLEEIAMKYVLATGSLRPELRKKKVFCFAADHGVAVEGVSAF
PAEVTPQMVYNMLAGGAAINVLSRHAGADLDVVDMGVHHDFVEHPSLRICKVRHGSSNMAEGPAMTMDETLQAIMTGVSL
AHEARKEGYDLLATGEMGIANTTPATALYASMLDLPVEMITGRGTGIDDAVLQHKISVIKRALDVNSASLSTPLEQLAAL
GGFEIAGICGLILGAASVGMPVVVDGFISSAGAVAALKLSCRVSDYLFFSHLSNEQGHKAIMNRLGARPILDLDLRLGEG
TGAALAMQVVEASVKLYNEMATFSSASVSGKSV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=349, Percent_Identity=37.8223495702006, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_PROA2 (B4S893)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002015927.1
- ProteinModelPortal:   B4S893
- SMR:   B4S893
- GeneID:   6460759
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_1254
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   PRK00105
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 37238; Mature: 37238

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: ACT_SITE 319-319

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQFQQVLASVKSVDMSLTKEVQAHLDDLTKPRGSLGRLEEIAMKYVLATGSLRPELRK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
KKVFCFAADHGVAVEGVSAFPAEVTPQMVYNMLAGGAAINVLSRHAGADLDVVDMGVHHD
CEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCHHH
FVEHPSLRICKVRHGSSNMAEGPAMTMDETLQAIMTGVSLAHEARKEGYDLLATGEMGIA
HHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
NTTPATALYASMLDLPVEMITGRGTGIDDAVLQHKISVIKRALDVNSASLSTPLEQLAAL
CCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GGFEIAGICGLILGAASVGMPVVVDGFISSAGAVAALKLSCRVSDYLFFSHLSNEQGHKA
CCCHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHH
IMNRLGARPILDLDLRLGEGTGAALAMQVVEASVKLYNEMATFSSASVSGKSV
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIEQFQQVLASVKSVDMSLTKEVQAHLDDLTKPRGSLGRLEEIAMKYVLATGSLRPELRK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
KKVFCFAADHGVAVEGVSAFPAEVTPQMVYNMLAGGAAINVLSRHAGADLDVVDMGVHHD
CEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCHHH
FVEHPSLRICKVRHGSSNMAEGPAMTMDETLQAIMTGVSLAHEARKEGYDLLATGEMGIA
HHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
NTTPATALYASMLDLPVEMITGRGTGIDDAVLQHKISVIKRALDVNSASLSTPLEQLAAL
CCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GGFEIAGICGLILGAASVGMPVVVDGFISSAGAVAALKLSCRVSDYLFFSHLSNEQGHKA
CCCHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHH
IMNRLGARPILDLDLRLGEGTGAALAMQVVEASVKLYNEMATFSSASVSGKSV
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA