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The map label for this gene is cusC [C]

Identifier: 194333961

GI number: 194333961

Start: 1248679

End: 1249998

Strand: Reverse

Name: cusC [C]

Synonym: Paes_1145

Alternate gene names: 194333961

Gene position: 1249998-1248679 (Counterclockwise)

Preceding gene: 194333962

Following gene: 194333960

Centisome position: 49.74

GC content: 53.94

Gene sequence:

>1320_bases
ATGTTTACTTGCAGAACCATGACAACCATGCAGAGAAAAGATCATATGATATTTTATCGACGCTATCGTATGGCGCTTTT
GACGCTTCTTTTTTTTATTGCCGCTTCTGCTGCACAAGCAGGAGAAGTCCTGACGTGGGACGCATGTGTCAACGAGGCTC
TTCTGAACCAGCCCGACCTGTTATCCTCACGCGCTTCTATCGATGAGGCCGGGGCCACGAGGCGTATCACTGCCTCATCA
GGACTTCCGCAGGTGCAGGCAGGGCTCAGCGCAACACAGAGCGGCACGACAGAAGGAAGCGGCTCTTCGTCGTCATCCTT
CTCCTATTGGCTTTCAGCTTCCCAGCTGCTCTATGACGGAGGATCGACATCGAGCCTTATTGCAGGCGCAGACGAGTCGA
TCAACGCCGCCCGATACCGTTACGGTACTGTTTCGTCTGAAGTGCGCTTTGCGCTCAGGACAGCATTTGTCGACCTCCTG
AAAGCACAGGAGCTTGTCGGCCTTGCCGGAGAAATTGCTGAACGCCGAAAGAAAAACGTTCGTCTTCTGCAGCTTCGTTA
TAATGCGGGACGGGAGCACATCGGCTCGCTCAGGCGAGCTGAAGCCGATATGGCCGAAGCGGCATTCGAGGTTGCCCAGG
CTGAGCGTGCTCTTGTTCTTGCCCGTTCGAAACTCGCTTCGGCACTCGGGCGTGACCAGCGTTCTGTCGTGAGCGTGAAA
GGCTCGTTCAAAGCATCGGAGTCGCTCGTGTCCACTCCCCAGTTCAGTGTTCTTGCGCGCCAGAACCCTCAGGTCCAGCA
GCTTGAAGCTGTCGAGAGGTCGGCCCGGCACGATCTCGACGCCTCCAGGCATGCTTTCGCTCCCGCACTTTCTCTGACGT
CATCTGTAGGAAGAAGCTCCTTTGATCAGTTGCCGGTCGACGCACTTGACTGGAATGCCGGTTTTTCGGTCTCTATACCG
ATTATCGAGGGGGGCAGTGGCAGGGCAAACGTTGCCAAAGCGCTTGCAGCACTCAATAACAAGGCAGGGCAGGAGCAGAG
CGGTTATCTGCAGGTGCTCGATACGCTCGAAGAGAGCTGGAAGAATTTTCAGGATGCATCAGAAAACGTCGGCGTGCAGA
AAAAATTTCTCGAAGCGGCCGCTGAACGTTCCACGATCGCAAATGCTCAGTATTCCAATGGCTTGATCAGTTTTGACGAC
TGGGTCATTATCGAGGATAATCTTGTGAGTTCAAAAAAATCATATCTCAATGCCGAGGCGGAACTTCTGCTTGCCGAGGC
CCAGTGGATGAAGGCAAAAGGAGTGACATTGCATGAATAA

Upstream 100 bases:

>100_bases
GATGATGACGGGGCCAGACAGGAACTGACACCTGAGCTGACCTGTTAGTCCGACCGACAATTTGAAGCGTTTTCAGCGTC
ATACAGAGGAATCTGTTACG

Downstream 100 bases:

>100_bases
GAAACCTCTCATCATCGCGCTTGTCGTTCTGTTGGTTTCCGGTGCGGCAACTGGAGTCTGGTTCATGGTGTTGAGCAAGA
AGGAGCCGTCAGCCGAGTTT

Product: outer membrane efflux protein

Products: NA

Alternate protein names: FusA/NodT Family Protein; Type I Secretion Outer Membrane Protein; Outer Membrane Efflux Protein lC

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFTCRTMTTMQRKDHMIFYRRYRMALLTLLFFIAASAAQAGEVLTWDACVNEALLNQPDLLSSRASIDEAGATRRITASS
GLPQVQAGLSATQSGTTEGSGSSSSSFSYWLSASQLLYDGGSTSSLIAGADESINAARYRYGTVSSEVRFALRTAFVDLL
KAQELVGLAGEIAERRKKNVRLLQLRYNAGREHIGSLRRAEADMAEAAFEVAQAERALVLARSKLASALGRDQRSVVSVK
GSFKASESLVSTPQFSVLARQNPQVQQLEAVERSARHDLDASRHAFAPALSLTSSVGRSSFDQLPVDALDWNAGFSVSIP
IIEGGSGRANVAKALAALNNKAGQEQSGYLQVLDTLEESWKNFQDASENVGVQKKFLEAAAERSTIANAQYSNGLISFDD
WVIIEDNLVSSKKSYLNAEAELLLAEAQWMKAKGVTLHE

Sequences:

>Translated_439_residues
MFTCRTMTTMQRKDHMIFYRRYRMALLTLLFFIAASAAQAGEVLTWDACVNEALLNQPDLLSSRASIDEAGATRRITASS
GLPQVQAGLSATQSGTTEGSGSSSSSFSYWLSASQLLYDGGSTSSLIAGADESINAARYRYGTVSSEVRFALRTAFVDLL
KAQELVGLAGEIAERRKKNVRLLQLRYNAGREHIGSLRRAEADMAEAAFEVAQAERALVLARSKLASALGRDQRSVVSVK
GSFKASESLVSTPQFSVLARQNPQVQQLEAVERSARHDLDASRHAFAPALSLTSSVGRSSFDQLPVDALDWNAGFSVSIP
IIEGGSGRANVAKALAALNNKAGQEQSGYLQVLDTLEESWKNFQDASENVGVQKKFLEAAAERSTIANAQYSNGLISFDD
WVIIEDNLVSSKKSYLNAEAELLLAEAQWMKAKGVTLHE
>Mature_439_residues
MFTCRTMTTMQRKDHMIFYRRYRMALLTLLFFIAASAAQAGEVLTWDACVNEALLNQPDLLSSRASIDEAGATRRITASS
GLPQVQAGLSATQSGTTEGSGSSSSSFSYWLSASQLLYDGGSTSSLIAGADESINAARYRYGTVSSEVRFALRTAFVDLL
KAQELVGLAGEIAERRKKNVRLLQLRYNAGREHIGSLRRAEADMAEAAFEVAQAERALVLARSKLASALGRDQRSVVSVK
GSFKASESLVSTPQFSVLARQNPQVQQLEAVERSARHDLDASRHAFAPALSLTSSVGRSSFDQLPVDALDWNAGFSVSIP
IIEGGSGRANVAKALAALNNKAGQEQSGYLQVLDTLEESWKNFQDASENVGVQKKFLEAAAERSTIANAQYSNGLISFDD
WVIIEDNLVSSKKSYLNAEAELLLAEAQWMKAKGVTLHE

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786785, Length=393, Percent_Identity=23.6641221374046, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47567; Mature: 47567

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTCRTMTTMQRKDHMIFYRRYRMALLTLLFFIAASAAQAGEVLTWDACVNEALLNQPDL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCHH
LSSRASIDEAGATRRITASSGLPQVQAGLSATQSGTTEGSGSSSSSFSYWLSASQLLYDG
HHHHCCHHHCCCCEEEECCCCCCHHHHCCHHCCCCCCCCCCCCCCCHHHHCCHHHHEECC
GSTSSLIAGADESINAARYRYGTVSSEVRFALRTAFVDLLKAQELVGLAGEIAERRKKNV
CCCCCEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLLQLRYNAGREHIGSLRRAEADMAEAAFEVAQAERALVLARSKLASALGRDQRSVVSVK
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEC
GSFKASESLVSTPQFSVLARQNPQVQQLEAVERSARHDLDASRHAFAPALSLTSSVGRSS
CCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCH
FDQLPVDALDWNAGFSVSIPIIEGGSGRANVAKALAALNNKAGQEQSGYLQVLDTLEESW
HHCCCCCCEECCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KNFQDASENVGVQKKFLEAAAERSTIANAQYSNGLISFDDWVIIEDNLVSSKKSYLNAEA
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCEECCCEEEEECCHHHHHHHHHCCHH
ELLLAEAQWMKAKGVTLHE
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFTCRTMTTMQRKDHMIFYRRYRMALLTLLFFIAASAAQAGEVLTWDACVNEALLNQPDL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCHH
LSSRASIDEAGATRRITASSGLPQVQAGLSATQSGTTEGSGSSSSSFSYWLSASQLLYDG
HHHHCCHHHCCCCEEEECCCCCCHHHHCCHHCCCCCCCCCCCCCCCHHHHCCHHHHEECC
GSTSSLIAGADESINAARYRYGTVSSEVRFALRTAFVDLLKAQELVGLAGEIAERRKKNV
CCCCCEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLLQLRYNAGREHIGSLRRAEADMAEAAFEVAQAERALVLARSKLASALGRDQRSVVSVK
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEC
GSFKASESLVSTPQFSVLARQNPQVQQLEAVERSARHDLDASRHAFAPALSLTSSVGRSS
CCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCH
FDQLPVDALDWNAGFSVSIPIIEGGSGRANVAKALAALNNKAGQEQSGYLQVLDTLEESW
HHCCCCCCEECCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KNFQDASENVGVQKKFLEAAAERSTIANAQYSNGLISFDDWVIIEDNLVSSKKSYLNAEA
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCEECCCEEEEECCHHHHHHHHHCCHH
ELLLAEAQWMKAKGVTLHE
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA