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The map label for this gene is ycgM [H]

Identifier: 194333865

GI number: 194333865

Start: 1141756

End: 1142475

Strand: Reverse

Name: ycgM [H]

Synonym: Paes_1039

Alternate gene names: 194333865

Gene position: 1142475-1141756 (Counterclockwise)

Preceding gene: 194333871

Following gene: 194333864

Centisome position: 45.46

GC content: 52.22

Gene sequence:

>720_bases
ATGCCTCTTATTCCAGCCGCCACACTCGCCCCGTCATCGATCTACTGTGTAGGAAAAAACTATGAAGATCATGCCAGAGA
AATGCTGAAATGGGACGGGGGCACAACGCTCCCGCCCCTGAATGAGTCTGACCCCATTATCTTTCTCAAACCCGTTTCAG
CTCTTACGCCTGACTACAGAACATCGATCCCCTGTATCGAACAGCAACCGGTATCGCACCTTATGCATTACGAAGCCGAA
CTGGTGCTCCTCATTGGAAAGGATGCAGAGCAAATAGGGCTCGACGAAGCGCCCCGATATATTCAAGGCTACGGTGTCGG
TCTTGACATGACACTGCGCGACGTCCAGCAGCAGGCCCGACAAAAAGGAGAGCCATGGCTGAAAAGCAAAGGTTTCCGTC
AAAGCGCTATGGTCTCGGATATCATAACCGCTGAAGATGCCGGAGATCCGGCCTCTCTTGGTTTTTCTCTCATCCTGAAC
GGCAAAAAAGTCCAGCAGGGGGCGGCAAACCAGATGATATTCAATCCCTTTCATCTTATTTCCTATCTTTCATGGATATA
TGGTTTGCGCCGGGGAGACCTTCTGTTTACCGGCACACCGGCAGGCGTCGGACCGGTTGAACCGGGTGATCGCCTCGAAG
CGATTCTGGAACAAACACATAACGGGGCCGCAACAGCCCTGACGCATTTCGAAGCAACAATCCATGAACCCGGCACATAA

Upstream 100 bases:

>100_bases
TACCGGATTTTCACTTTATCCATTACAATCCAGCTCCCGGCAAGAGAAGCGGATTGGCAATACTGAAAGCCCTGCAACAA
ACAATATCTTTTTTACCGAC

Downstream 100 bases:

>100_bases
GAGCCTGCCGTCATCCAAACAAAACTTTTCCGTTAACACTACAGCGAGCAAGCATGAGCATCATTTTTCATCAGGCGAGA
ATCATCAATCCCGCCCAGAA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MPLIPAATLAPSSIYCVGKNYEDHAREMLKWDGGTTLPPLNESDPIIFLKPVSALTPDYRTSIPCIEQQPVSHLMHYEAE
LVLLIGKDAEQIGLDEAPRYIQGYGVGLDMTLRDVQQQARQKGEPWLKSKGFRQSAMVSDIITAEDAGDPASLGFSLILN
GKKVQQGAANQMIFNPFHLISYLSWIYGLRRGDLLFTGTPAGVGPVEPGDRLEAILEQTHNGAATALTHFEATIHEPGT

Sequences:

>Translated_239_residues
MPLIPAATLAPSSIYCVGKNYEDHAREMLKWDGGTTLPPLNESDPIIFLKPVSALTPDYRTSIPCIEQQPVSHLMHYEAE
LVLLIGKDAEQIGLDEAPRYIQGYGVGLDMTLRDVQQQARQKGEPWLKSKGFRQSAMVSDIITAEDAGDPASLGFSLILN
GKKVQQGAANQMIFNPFHLISYLSWIYGLRRGDLLFTGTPAGVGPVEPGDRLEAILEQTHNGAATALTHFEATIHEPGT
>Mature_238_residues
PLIPAATLAPSSIYCVGKNYEDHAREMLKWDGGTTLPPLNESDPIIFLKPVSALTPDYRTSIPCIEQQPVSHLMHYEAEL
VLLIGKDAEQIGLDEAPRYIQGYGVGLDMTLRDVQQQARQKGEPWLKSKGFRQSAMVSDIITAEDAGDPASLGFSLILNG
KKVQQGAANQMIFNPFHLISYLSWIYGLRRGDLLFTGTPAGVGPVEPGDRLEAILEQTHNGAATALTHFEATIHEPGT

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=210, Percent_Identity=38.5714285714286, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=39.6039603960396, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=39.6039603960396, Blast_Score=141, Evalue=4e-34,
Organism=Homo sapiens, GI156231349, Length=221, Percent_Identity=31.6742081447964, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI40786394, Length=216, Percent_Identity=31.0185185185185, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1787428, Length=212, Percent_Identity=38.6792452830189, Blast_Score=145, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=215, Percent_Identity=33.4883720930233, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324161, Length=242, Percent_Identity=29.3388429752066, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571789, Length=171, Percent_Identity=35.0877192982456, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28572127, Length=220, Percent_Identity=29.5454545454545, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 26109; Mature: 25978

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLIPAATLAPSSIYCVGKNYEDHAREMLKWDGGTTLPPLNESDPIIFLKPVSALTPDYR
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHCCCCCC
TSIPCIEQQPVSHLMHYEAELVLLIGKDAEQIGLDEAPRYIQGYGVGLDMTLRDVQQQAR
CCCCCCCCHHHHHHHHCCCEEEEEECCCHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHH
QKGEPWLKSKGFRQSAMVSDIITAEDAGDPASLGFSLILNGKKVQQGAANQMIFNPFHLI
HCCCCCHHCCCCCHHHHHHHHHHCCCCCCHHHCCEEEEECCCHHHCCCCCCEEECHHHHH
SYLSWIYGLRRGDLLFTGTPAGVGPVEPGDRLEAILEQTHNGAATALTHFEATIHEPGT
HHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
PLIPAATLAPSSIYCVGKNYEDHAREMLKWDGGTTLPPLNESDPIIFLKPVSALTPDYR
CCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHCCCCCC
TSIPCIEQQPVSHLMHYEAELVLLIGKDAEQIGLDEAPRYIQGYGVGLDMTLRDVQQQAR
CCCCCCCCHHHHHHHHCCCEEEEEECCCHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHH
QKGEPWLKSKGFRQSAMVSDIITAEDAGDPASLGFSLILNGKKVQQGAANQMIFNPFHLI
HCCCCCHHCCCCCHHHHHHHHHHCCCCCCHHHCCEEEEECCCHHHCCCCCCEEECHHHHH
SYLSWIYGLRRGDLLFTGTPAGVGPVEPGDRLEAILEQTHNGAATALTHFEATIHEPGT
HHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]