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The map label for this gene is cobB [H]

Identifier: 193212844

GI number: 193212844

Start: 1304892

End: 1306220

Strand: Direct

Name: cobB [H]

Synonym: Cpar_1191

Alternate gene names: 193212844

Gene position: 1304892-1306220 (Clockwise)

Preceding gene: 193212843

Following gene: 193212853

Centisome position: 57.0

GC content: 63.28

Gene sequence:

>1329_bases
ATGAAGAGTAATCGTGGCTTTCTCATCGCCGCCCCGTCGAGCGGCTCCGGCAAGACGACTATCACCCTCGGTCTGTTGCG
GCTTTTCGCGCGGCGCGGCATGGAGGTGCAGCCCTTCAAGTGCGGGCCGGACTACCTCGACACGATGCTGCACGCGATGG
CCGCTTCGACCGGAGAAGCCTCGAAACCGGGCCTCAATCTCGATACCTTCATGGCCTCGAAAGAGCACGTGCGTTCGCTC
TTCGCCAGCCACGCGGCATCGGCAGACATCTCGATGGTCGAGGGGGTGATGGGGCTGTTTGACGGAGCCGAGCGCTCGAA
CGGCAGCAGCGCCGAGATCGCCACCTTGCTTGGCCTACCGGTCATCATGGTGATCGATGGTTCGAAGATGGCCTACTCGG
CAGCGCCGATCCTGTACGGATTCAAGAACTTCGACCCGTCGGTCAACGTGGCGGGCGTGATCTTCAACCGCGTCGGCAGC
GCGTCGCACTACAGCTACCTCGAAGCCGCCGCGAAGGACGTTGGCGTCGAACCGCTCGGCTACCTGCCGCGCAACAGCGC
CATCACCATCGACGAGCGACACCTCGGCCTCAACACCTCGGCGGAGTACGACCGCGAAAAGCTCATCGATGCGATGGCCG
ACCACATCGAAAAAACGGTCAACATCGAGCGGTTGCTCGAAGTGGCGCGGATCGAACTGCCGGAAGTCGAACCGATCCGT
CCGGTGGCGAAAAAGTCGGGCAAGATGATCGCCGTGGCGCGGGACGAAGCGTTCAACTTCATCTACCACGCCAACATCGA
GGCGCTCAAGCAGTACGGCGAGGTGCGCTTCTTCAGCCCGCTGCACGACCACGAGCTACCCGAAGCCGACCTGGTTTACC
TCGCCGGAGGCTACCCGGAGCTGCACGCGCGAGCGCTTGCCGCGAACGCCGAAATGCGCAATGCTATCGCTGAATGGTGC
CGCAACGGAGGCGCGACCTACGCCGAATGCGGTGGTCTGATGTACCTCGGCCAGACGCTCACCCTCGCCGACGGGGCGAC
CCACCCGATGTGCGGCGTGCTCGACCTCGACACCACCATGCAGGAGGCCCGCCTCACGCTCGGCTACCGCAAGGTGTATC
CGGCGGATGCGAACGGTGTGGAGCTGCGAGGCCACGAATTCCACTACTCCCGCATCTCGCGGCAAGGCGAAATCGACACC
ATCGCCGAAATCCGCAACGCCCGCGACCAAGAGGTTCCAACCAGCCTCTTCCGCGTCGGCAACACCATCGCCTCCTACCT
GCACCTCTACTGGGGCGAACGCGACCATCTCGCTAACTGGTTTTTCTGA

Upstream 100 bases:

>100_bases
AACGACCGGGTTTACGACAAGTTCGACAACCGCCTCTACCTGCGCCCCGGCCCGCGCATCCTCGAAGGCATCGCCGGAAT
GAAAAAGCTGATCGAGAGCA

Downstream 100 bases:

>100_bases
ATACAGTTATAAACGAATCAGCATGACAGCTGACCTCAGCGGTTCGTTCGCCGGAATGTGAACCAGGCGAACTCCTGCGT
CGAGCCGGAAGGAGTAAGAT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKSNRGFLIAAPSSGSGKTTITLGLLRLFARRGMEVQPFKCGPDYLDTMLHAMAASTGEASKPGLNLDTFMASKEHVRSL
FASHAASADISMVEGVMGLFDGAERSNGSSAEIATLLGLPVIMVIDGSKMAYSAAPILYGFKNFDPSVNVAGVIFNRVGS
ASHYSYLEAAAKDVGVEPLGYLPRNSAITIDERHLGLNTSAEYDREKLIDAMADHIEKTVNIERLLEVARIELPEVEPIR
PVAKKSGKMIAVARDEAFNFIYHANIEALKQYGEVRFFSPLHDHELPEADLVYLAGGYPELHARALAANAEMRNAIAEWC
RNGGATYAECGGLMYLGQTLTLADGATHPMCGVLDLDTTMQEARLTLGYRKVYPADANGVELRGHEFHYSRISRQGEIDT
IAEIRNARDQEVPTSLFRVGNTIASYLHLYWGERDHLANWFF

Sequences:

>Translated_442_residues
MKSNRGFLIAAPSSGSGKTTITLGLLRLFARRGMEVQPFKCGPDYLDTMLHAMAASTGEASKPGLNLDTFMASKEHVRSL
FASHAASADISMVEGVMGLFDGAERSNGSSAEIATLLGLPVIMVIDGSKMAYSAAPILYGFKNFDPSVNVAGVIFNRVGS
ASHYSYLEAAAKDVGVEPLGYLPRNSAITIDERHLGLNTSAEYDREKLIDAMADHIEKTVNIERLLEVARIELPEVEPIR
PVAKKSGKMIAVARDEAFNFIYHANIEALKQYGEVRFFSPLHDHELPEADLVYLAGGYPELHARALAANAEMRNAIAEWC
RNGGATYAECGGLMYLGQTLTLADGATHPMCGVLDLDTTMQEARLTLGYRKVYPADANGVELRGHEFHYSRISRQGEIDT
IAEIRNARDQEVPTSLFRVGNTIASYLHLYWGERDHLANWFF
>Mature_442_residues
MKSNRGFLIAAPSSGSGKTTITLGLLRLFARRGMEVQPFKCGPDYLDTMLHAMAASTGEASKPGLNLDTFMASKEHVRSL
FASHAASADISMVEGVMGLFDGAERSNGSSAEIATLLGLPVIMVIDGSKMAYSAAPILYGFKNFDPSVNVAGVIFNRVGS
ASHYSYLEAAAKDVGVEPLGYLPRNSAITIDERHLGLNTSAEYDREKLIDAMADHIEKTVNIERLLEVARIELPEVEPIR
PVAKKSGKMIAVARDEAFNFIYHANIEALKQYGEVRFFSPLHDHELPEADLVYLAGGYPELHARALAANAEMRNAIAEWC
RNGGATYAECGGLMYLGQTLTLADGATHPMCGVLDLDTTMQEARLTLGYRKVYPADANGVELRGHEFHYSRISRQGEIDT
IAEIRNARDQEVPTSLFRVGNTIASYLHLYWGERDHLANWFF

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 48441; Mature: 48441

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNRGFLIAAPSSGSGKTTITLGLLRLFARRGMEVQPFKCGPDYLDTMLHAMAASTGEA
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SKPGLNLDTFMASKEHVRSLFASHAASADISMVEGVMGLFDGAERSNGSSAEIATLLGLP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
VIMVIDGSKMAYSAAPILYGFKNFDPSVNVAGVIFNRVGSASHYSYLEAAAKDVGVEPLG
EEEEECCCCCEECCCHHHEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
YLPRNSAITIDERHLGLNTSAEYDREKLIDAMADHIEKTVNIERLLEVARIELPEVEPIR
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
PVAKKSGKMIAVARDEAFNFIYHANIEALKQYGEVRFFSPLHDHELPEADLVYLAGGYPE
HHHHCCCCEEEEECCCCEEEEEECCHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCHH
LHARALAANAEMRNAIAEWCRNGGATYAECGGLMYLGQTLTLADGATHPMCGVLDLDTTM
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCEEEECCCCCCCCCEEEECHHHH
QEARLTLGYRKVYPADANGVELRGHEFHYSRISRQGEIDTIAEIRNARDQEVPTSLFRVG
HHHHHHHHHEEECCCCCCCEEECCCEEHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHH
NTIASYLHLYWGERDHLANWFF
HHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MKSNRGFLIAAPSSGSGKTTITLGLLRLFARRGMEVQPFKCGPDYLDTMLHAMAASTGEA
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SKPGLNLDTFMASKEHVRSLFASHAASADISMVEGVMGLFDGAERSNGSSAEIATLLGLP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
VIMVIDGSKMAYSAAPILYGFKNFDPSVNVAGVIFNRVGSASHYSYLEAAAKDVGVEPLG
EEEEECCCCCEECCCHHHEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
YLPRNSAITIDERHLGLNTSAEYDREKLIDAMADHIEKTVNIERLLEVARIELPEVEPIR
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
PVAKKSGKMIAVARDEAFNFIYHANIEALKQYGEVRFFSPLHDHELPEADLVYLAGGYPE
HHHHCCCCEEEEECCCCEEEEEECCHHHHHHCCCEEEECCCCCCCCCCCCEEEEECCCHH
LHARALAANAEMRNAIAEWCRNGGATYAECGGLMYLGQTLTLADGATHPMCGVLDLDTTM
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCEEEECCCCCCCCCEEEECHHHH
QEARLTLGYRKVYPADANGVELRGHEFHYSRISRQGEIDTIAEIRNARDQEVPTSLFRVG
HHHHHHHHHEEECCCCCCCEEECCCEEHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHH
NTIASYLHLYWGERDHLANWFF
HHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]