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The map label for this gene is hldE [H]

Identifier: 193212766

GI number: 193212766

Start: 1229780

End: 1230772

Strand: Direct

Name: hldE [H]

Synonym: Cpar_1112

Alternate gene names: 193212766

Gene position: 1229780-1230772 (Clockwise)

Preceding gene: 193212759

Following gene: 193212771

Centisome position: 53.72

GC content: 56.8

Gene sequence:

>993_bases
ATGCCCGCCGAAATTATCGAACACATTTTTCAGACCTTCAAACACCGGAAAATTGCCGTTATCGGCGATCTGATGATCGA
TAAGTATATCTTCGGCCATGTTTCGCGCATCTCGCCGGAATATCCGGTGCCGGTGGTCGATGTTTCCCGTGAAGACAGCC
GACTCGGCGGAGCGGCCAACGTGGCGATCAACACTCATGTACTCGGTGCCGAAACCCTCCTGATAGGCGTAACCGGTCAG
GATGCGGAGCGCGAGAACCTCCTCAGACTGATGCAGGAGCAGGAGCTCGATACGGGCATGATCGTAGCCGACCCTTCGCG
CCCCACCACCTGCAAAACCCGCATCCTCTCACAGAACCACCATATCACCCGGGTCGATTACGAGCGGCGCCATCCGCTCG
ATGCGGCAATCGAAGCGCAACTGCTCGGCATGTTCCGGGAAGTCGCGCCGTCACTGGACGCAGTGGTACTTGAAGACTAT
AATAAAGGAGTGCTCACCCCGTCACTGGTCGAAGCGGTCATCACAACCTGCAAGGCACTGAATGTGCCGGTACTGGTCGA
TCCGAAGCTCAAGGGATTTTTCTCCTACAGCGGCTGCACGGTCTTCAAGCCAAATCTCTCAGAACTCGCCGCATCGCTCG
GTATTGCAGTGAGCAACGACGACAGCGAGGTCGAAAATGCCTGCCTTCAGCTTGTAGAAAAACTCGTGGTATCAAGCCTC
GTGGTGACCCGAAGCGAAAAAGGCATGACGGTCTACGACGGCAAATTCACTCACCTTCCGGCCATCTCGCTCGATGTGGC
CGATGTATCAGGCGCCGGCGATACGGTGATCGCCCTCTTGGCGCTCGGCATGGCCTCGGACCTCGACCTGGTCACCAGCA
CCCGGATAGCCAATCTTGCAGCCCACACCGTCTGTCAGGAGGTCGGCGCAGTACCGGTCAGGCCGGAAAAACTCTTCAAC
GCCTGCATAGCCCATTTGAGGAACTCTTTATAA

Upstream 100 bases:

>100_bases
TAAATATAAAAAAATTATCATAAAATAAAACCAGTCAATGCAATGACCCTCATGGTATTTTTCCTTTATATTTACCTGAC
TTCAATTTAACCTGTCACCC

Downstream 100 bases:

>100_bases
CAACAAGGGTTGGCGGCTCAAGTTCCACTCAGGAAATGTGGATGTGGTTATCGACCACTGATGGCCACGGTGGCGCGTAC
GAGGAGTCCTGCGCCAGCGA

Product: rfaE bifunctional protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPAEIIEHIFQTFKHRKIAVIGDLMIDKYIFGHVSRISPEYPVPVVDVSREDSRLGGAANVAINTHVLGAETLLIGVTGQ
DAERENLLRLMQEQELDTGMIVADPSRPTTCKTRILSQNHHITRVDYERRHPLDAAIEAQLLGMFREVAPSLDAVVLEDY
NKGVLTPSLVEAVITTCKALNVPVLVDPKLKGFFSYSGCTVFKPNLSELAASLGIAVSNDDSEVENACLQLVEKLVVSSL
VVTRSEKGMTVYDGKFTHLPAISLDVADVSGAGDTVIALLALGMASDLDLVTSTRIANLAAHTVCQEVGAVPVRPEKLFN
ACIAHLRNSL

Sequences:

>Translated_330_residues
MPAEIIEHIFQTFKHRKIAVIGDLMIDKYIFGHVSRISPEYPVPVVDVSREDSRLGGAANVAINTHVLGAETLLIGVTGQ
DAERENLLRLMQEQELDTGMIVADPSRPTTCKTRILSQNHHITRVDYERRHPLDAAIEAQLLGMFREVAPSLDAVVLEDY
NKGVLTPSLVEAVITTCKALNVPVLVDPKLKGFFSYSGCTVFKPNLSELAASLGIAVSNDDSEVENACLQLVEKLVVSSL
VVTRSEKGMTVYDGKFTHLPAISLDVADVSGAGDTVIALLALGMASDLDLVTSTRIANLAAHTVCQEVGAVPVRPEKLFN
ACIAHLRNSL
>Mature_329_residues
PAEIIEHIFQTFKHRKIAVIGDLMIDKYIFGHVSRISPEYPVPVVDVSREDSRLGGAANVAINTHVLGAETLLIGVTGQD
AERENLLRLMQEQELDTGMIVADPSRPTTCKTRILSQNHHITRVDYERRHPLDAAIEAQLLGMFREVAPSLDAVVLEDYN
KGVLTPSLVEAVITTCKALNVPVLVDPKLKGFFSYSGCTVFKPNLSELAASLGIAVSNDDSEVENACLQLVEKLVVSSLV
VTRSEKGMTVYDGKFTHLPAISLDVADVSGAGDTVIALLALGMASDLDLVTSTRIANLAAHTVCQEVGAVPVRPEKLFNA
CIAHLRNSL

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=317, Percent_Identity=38.801261829653, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35717; Mature: 35585

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAEIIEHIFQTFKHRKIAVIGDLMIDKYIFGHVSRISPEYPVPVVDVSREDSRLGGAAN
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEE
VAINTHVLGAETLLIGVTGQDAERENLLRLMQEQELDTGMIVADPSRPTTCKTRILSQNH
EEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCC
HITRVDYERRHPLDAAIEAQLLGMFREVAPSLDAVVLEDYNKGVLTPSLVEAVITTCKAL
CEEEECCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
NVPVLVDPKLKGFFSYSGCTVFKPNLSELAASLGIAVSNDDSEVENACLQLVEKLVVSSL
CCCEEECCCCCCEEEECCEEEECCCHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHH
VVTRSEKGMTVYDGKFTHLPAISLDVADVSGAGDTVIALLALGMASDLDLVTSTRIANLA
HHCCCCCCCEEECCCEEECCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
AHTVCQEVGAVPVRPEKLFNACIAHLRNSL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAEIIEHIFQTFKHRKIAVIGDLMIDKYIFGHVSRISPEYPVPVVDVSREDSRLGGAAN
CHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEE
VAINTHVLGAETLLIGVTGQDAERENLLRLMQEQELDTGMIVADPSRPTTCKTRILSQNH
EEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCC
HITRVDYERRHPLDAAIEAQLLGMFREVAPSLDAVVLEDYNKGVLTPSLVEAVITTCKAL
CEEEECCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
NVPVLVDPKLKGFFSYSGCTVFKPNLSELAASLGIAVSNDDSEVENACLQLVEKLVVSSL
CCCEEECCCCCCEEEECCEEEECCCHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHH
VVTRSEKGMTVYDGKFTHLPAISLDVADVSGAGDTVIALLALGMASDLDLVTSTRIANLA
HHCCCCCCCEEECCCEEECCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
AHTVCQEVGAVPVRPEKLFNACIAHLRNSL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA