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The map label for this gene is atpA1 [H]

Identifier: 193212726

GI number: 193212726

Start: 1177857

End: 1179383

Strand: Direct

Name: atpA1 [H]

Synonym: Cpar_1071

Alternate gene names: 193212726

Gene position: 1177857-1179383 (Clockwise)

Preceding gene: 193212725

Following gene: 193212727

Centisome position: 51.45

GC content: 63.98

Gene sequence:

>1527_bases
ATGCCAGATAAAAGCGGACATCCTCTGGACAAGGCACTCGACAGTGTCCGGCAGGCACGCGAAGGGTGGTCGGCTGATCT
GGCGCTCGTCGAGGAGGGCGTCGTGCGGACAGTGCTGAACGGCATCGTCAAGGTTGACGGCCTGCCGGGCGTCGGCTACG
AGGAGCTGGTGCGATTTCACGAAAACCTTTACGGCATCGCCTTCAACATCGATCCCGGCGAGGTGGGCGTGGTGCTGCTC
GGCGACTACGCCCGACTCAGAACTGGCGACAGGGCGTGGCGCACGGGCCGCGTTACCGACGTGCCGGTCGGCGAGCAGCT
CATCGGGCGCGTGATCGATCCGCTCGGCCAGCCGCTCGACGAACTCGGCCCAGTCAAAACCACCAAGCGGTGGCCGATCG
AGCGCCCCGCCCCGCCCATCATGGATCGCGATCCGGTGACCGTGCCGCTGCAAACCGGCATCAAGGTGATCGACGCCATC
GTGCCGGTCGGGCGGGGCCAGCGCGAGTTGATCCTCGGCGACCGGCAGACCGGCAAAACCTCTGTGGCGCTCTCGGCGAT
GATCAACCAGCGCCAGAACGAGGTGCTATGCATCTACTGCGCCATTGGTCAGAAAGCGGCTTCCGTCGCCAAGGCGGTCG
CGGTCTTGCGCGACCACGGCGCAATGGAGCACACCATCGTGCTGGTCACCGAAGGCAACGACCCGCCCGGCCTGCAATAC
ATCGCGCCGTACGCCGCCACCAGCATCGCCGAATATTTCATGCAGCAGGGGCGCGACGTGCTGATTGTTTACGACGATTT
GACGAATCACGCCCGCGCCTACCGCGAGCTGTCGCTGCTGCTCAAGCGCCCGCCCGGACGCGAGGCTTTTCCGGGCGACA
TCTTCTACATCCACTCTCGGCTTCTGGAACGTGCCACGCACCTGCGCCGCGAACTCGGCGGCGGCTCCTTGACCGCTCTG
CCGATCATCGAAACCGAGGCGCAGAACATCTCGGCCTACATCCCGACCAACCTGATCTCGATCACCGATGGCCAGCTCTA
TCTTTCGCCGACGCTTTTCGAGCTTGGCATTCTGCCCGCCGTTGACATCGGCAAATCGGTCTCGCGCGTTGGTGGCAAGG
CGCAACTCGCGGCCTACCGCGCGGTCACCGGCAGCCTCAAGCTCGCCTACGCGCAGTTCGAGGAGCTGGAAAACTTCGCC
CGTTTCGGCACGCGGCTGGACGAAGCGAGCCGCAACATCATCGAGCACGGCCAGCGCATCCGCGAGTGCTTCAAGCAGGA
CGAATTCGACGTCCTCTCGCTGCCCGAGCAGATGCTCATTCTGCTGGCGCTGACCGAAGGGAGCTTCGAGCGGATCGGGC
TTGAGGCGATACGCGAGGCGATGGACAAGGTGCAGGCATCGGCATCGGAATTACCGGAGGAGCTGGTGGCGCGAATTCTC
TCCGGCAAGGAGCTTGCCGACGACGACCGTCTTTTCATGCTCGAAATCGCGAACCGGGCGCTCGAACAGTTCGGAAAAAG
CTCATGA

Upstream 100 bases:

>100_bases
GATGGCTTGTGCATTTCGTGGCACTTCCAGGCGGCGCTAGACGCGCTGAAGCGAGCCGCCGACGAGTACCGTGATCGTGA
AACGGATAACGGAGCGGCGG

Downstream 100 bases:

>100_bases
GCGAATCGATTGAACTTCTGCGCAGCAAAATCGCGCACGCGGGCACACTCGGCTCGGTGGTTCGGACGATGAAAACGCTC
GCCGCAGTCAACATCCGCCA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MPDKSGHPLDKALDSVRQAREGWSADLALVEEGVVRTVLNGIVKVDGLPGVGYEELVRFHENLYGIAFNIDPGEVGVVLL
GDYARLRTGDRAWRTGRVTDVPVGEQLIGRVIDPLGQPLDELGPVKTTKRWPIERPAPPIMDRDPVTVPLQTGIKVIDAI
VPVGRGQRELILGDRQTGKTSVALSAMINQRQNEVLCIYCAIGQKAASVAKAVAVLRDHGAMEHTIVLVTEGNDPPGLQY
IAPYAATSIAEYFMQQGRDVLIVYDDLTNHARAYRELSLLLKRPPGREAFPGDIFYIHSRLLERATHLRRELGGGSLTAL
PIIETEAQNISAYIPTNLISITDGQLYLSPTLFELGILPAVDIGKSVSRVGGKAQLAAYRAVTGSLKLAYAQFEELENFA
RFGTRLDEASRNIIEHGQRIRECFKQDEFDVLSLPEQMLILLALTEGSFERIGLEAIREAMDKVQASASELPEELVARIL
SGKELADDDRLFMLEIANRALEQFGKSS

Sequences:

>Translated_508_residues
MPDKSGHPLDKALDSVRQAREGWSADLALVEEGVVRTVLNGIVKVDGLPGVGYEELVRFHENLYGIAFNIDPGEVGVVLL
GDYARLRTGDRAWRTGRVTDVPVGEQLIGRVIDPLGQPLDELGPVKTTKRWPIERPAPPIMDRDPVTVPLQTGIKVIDAI
VPVGRGQRELILGDRQTGKTSVALSAMINQRQNEVLCIYCAIGQKAASVAKAVAVLRDHGAMEHTIVLVTEGNDPPGLQY
IAPYAATSIAEYFMQQGRDVLIVYDDLTNHARAYRELSLLLKRPPGREAFPGDIFYIHSRLLERATHLRRELGGGSLTAL
PIIETEAQNISAYIPTNLISITDGQLYLSPTLFELGILPAVDIGKSVSRVGGKAQLAAYRAVTGSLKLAYAQFEELENFA
RFGTRLDEASRNIIEHGQRIRECFKQDEFDVLSLPEQMLILLALTEGSFERIGLEAIREAMDKVQASASELPEELVARIL
SGKELADDDRLFMLEIANRALEQFGKSS
>Mature_507_residues
PDKSGHPLDKALDSVRQAREGWSADLALVEEGVVRTVLNGIVKVDGLPGVGYEELVRFHENLYGIAFNIDPGEVGVVLLG
DYARLRTGDRAWRTGRVTDVPVGEQLIGRVIDPLGQPLDELGPVKTTKRWPIERPAPPIMDRDPVTVPLQTGIKVIDAIV
PVGRGQRELILGDRQTGKTSVALSAMINQRQNEVLCIYCAIGQKAASVAKAVAVLRDHGAMEHTIVLVTEGNDPPGLQYI
APYAATSIAEYFMQQGRDVLIVYDDLTNHARAYRELSLLLKRPPGREAFPGDIFYIHSRLLERATHLRRELGGGSLTALP
IIETEAQNISAYIPTNLISITDGQLYLSPTLFELGILPAVDIGKSVSRVGGKAQLAAYRAVTGSLKLAYAQFEELENFAR
FGTRLDEASRNIIEHGQRIRECFKQDEFDVLSLPEQMLILLALTEGSFERIGLEAIREAMDKVQASASELPEELVARILS
GKELADDDRLFMLEIANRALEQFGKSS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=439, Percent_Identity=48.2915717539863, Blast_Score=435, Evalue=1e-122,
Organism=Homo sapiens, GI4757810, Length=439, Percent_Identity=48.2915717539863, Blast_Score=435, Evalue=1e-122,
Organism=Homo sapiens, GI32189394, Length=293, Percent_Identity=29.0102389078498, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19913426, Length=299, Percent_Identity=28.0936454849498, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI19913428, Length=292, Percent_Identity=27.7397260273973, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI19913424, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1790172, Length=438, Percent_Identity=46.8036529680365, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1790170, Length=417, Percent_Identity=25.1798561151079, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788251, Length=269, Percent_Identity=32.7137546468402, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71988063, Length=444, Percent_Identity=46.8468468468468, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71988080, Length=444, Percent_Identity=46.8468468468468, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71988074, Length=444, Percent_Identity=43.018018018018, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17510931, Length=294, Percent_Identity=28.9115646258503, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=293, Percent_Identity=28.3276450511945, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=285, Percent_Identity=27.719298245614, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319370, Length=492, Percent_Identity=45.3252032520325, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322581, Length=290, Percent_Identity=30, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=299, Percent_Identity=27.7591973244147, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658560, Length=432, Percent_Identity=47.2222222222222, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24638766, Length=293, Percent_Identity=28.6689419795222, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281361666, Length=295, Percent_Identity=28.135593220339, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646341, Length=295, Percent_Identity=28.135593220339, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136796, Length=295, Percent_Identity=28.135593220339, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28574560, Length=327, Percent_Identity=29.0519877675841, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI20129479, Length=269, Percent_Identity=26.7657992565056, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583988, Length=194, Percent_Identity=26.8041237113402, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583986, Length=194, Percent_Identity=26.8041237113402, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583984, Length=194, Percent_Identity=26.8041237113402, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583992, Length=194, Percent_Identity=26.8041237113402, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017710
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55845; Mature: 55714

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKSGHPLDKALDSVRQAREGWSADLALVEEGVVRTVLNGIVKVDGLPGVGYEELVRFH
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHH
ENLYGIAFNIDPGEVGVVLLGDYARLRTGDRAWRTGRVTDVPVGEQLIGRVIDPLGQPLD
HCCEEEEEEECCCCEEEEEECCHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCHH
ELGPVKTTKRWPIERPAPPIMDRDPVTVPLQTGIKVIDAIVPVGRGQRELILGDRQTGKT
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
SVALSAMINQRQNEVLCIYCAIGQKAASVAKAVAVLRDHGAMEHTIVLVTEGNDPPGLQY
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEE
IAPYAATSIAEYFMQQGRDVLIVYDDLTNHARAYRELSLLLKRPPGREAFPGDIFYIHSR
ECHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LLERATHLRRELGGGSLTALPIIETEAQNISAYIPTNLISITDGQLYLSPTLFELGILPA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEECCCCEEEEECCEEEECCHHHHHCCCCH
VDIGKSVSRVGGKAQLAAYRAVTGSLKLAYAQFEELENFARFGTRLDEASRNIIEHGQRI
HHCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RECFKQDEFDVLSLPEQMLILLALTEGSFERIGLEAIREAMDKVQASASELPEELVARIL
HHHHCCCCCCHHHCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGKELADDDRLFMLEIANRALEQFGKSS
CCCCCCCCCCEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDKSGHPLDKALDSVRQAREGWSADLALVEEGVVRTVLNGIVKVDGLPGVGYEELVRFH
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHH
ENLYGIAFNIDPGEVGVVLLGDYARLRTGDRAWRTGRVTDVPVGEQLIGRVIDPLGQPLD
HCCEEEEEEECCCCEEEEEECCHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCHH
ELGPVKTTKRWPIERPAPPIMDRDPVTVPLQTGIKVIDAIVPVGRGQRELILGDRQTGKT
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
SVALSAMINQRQNEVLCIYCAIGQKAASVAKAVAVLRDHGAMEHTIVLVTEGNDPPGLQY
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEE
IAPYAATSIAEYFMQQGRDVLIVYDDLTNHARAYRELSLLLKRPPGREAFPGDIFYIHSR
ECHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LLERATHLRRELGGGSLTALPIIETEAQNISAYIPTNLISITDGQLYLSPTLFELGILPA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEECCCCEEEEECCEEEECCHHHHHCCCCH
VDIGKSVSRVGGKAQLAAYRAVTGSLKLAYAQFEELENFARFGTRLDEASRNIIEHGQRI
HHCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RECFKQDEFDVLSLPEQMLILLALTEGSFERIGLEAIREAMDKVQASASELPEELVARIL
HHHHCCCCCCHHHCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGKELADDDRLFMLEIANRALEQFGKSS
CCCCCCCCCCEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA