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The map label for this gene is gldA [H]

Identifier: 193212718

GI number: 193212718

Start: 1172366

End: 1173460

Strand: Direct

Name: gldA [H]

Synonym: Cpar_1063

Alternate gene names: 193212718

Gene position: 1172366-1173460 (Clockwise)

Preceding gene: 193212717

Following gene: 193212719

Centisome position: 51.21

GC content: 59.82

Gene sequence:

>1095_bases
ATGCTAAACAAAGTCTTTTTTCCGGGGAAATATATTCAGGGAGCAGGCGCGCTCGACGAGTTGCCTGAGCTTATCCGCTC
ATTCGGCAAATGCGGCTTGCTGCTCGGGTCGCCGACGGTGCTGGAAACAATCCTTCCGGACAGCGGTCTGGATGTTCAAA
GCGGGCTGTTGAATACCGAGCTGTTTCATGGCGAGTGCTCGGCAACCGAGCTGTCGAGACTGGAAAAAGTGATCCGTGAG
CGGAAAAGCGACGTGCTGGTGGGTATGGGTGGCGGCAAAACGATCGACGCTGCCAAGGTCGCTGCTGATCGCGCTGGCGT
TCCGGTCATCATCGTACCGACCATCGCATCAACCGATGCTCCATGCAGCGGTTGCGCCGTGGTCTATTCCGACGATGGCG
CGTTCGAATCGGTCGCGTATCAGAAATCGAATCCGGCGGCGGTGCTGGTGGATCTGAACATTATCGCCAAGGCTCCGGCC
CGGTTCCTCGTAGCTGGTATGGGCGACGCACTGGCCACCTGGTTCGAAGCGCGCTCGTGCAGCGCCACCAAATCCCCGAA
TTCGTGCGGCGGACTCAGCACCCTGACCGGCCTCAGCCTCGCGCAGCTCTGTTACGACACGCTACTCCAGTACGGAAACG
CGGCCCGCATCGCAGCTGAACAGCAGGTGATCACGCCCGCACTTGAACACATCGTCGAAGCCAACATCCTTCTGAGCGGT
GTGGGATTTGAGAGCGGCGGACTGGCCAGTGCGCATTCGATTCACAACGGACTCACGGCGCTGCCCGAAACGCACCGCTT
TTATCACGGCGAAAAGGTGGCGTTTGGCACGCTTGCGGGACTGCACCTCACCGATGCAGATCCGGCTGAAATCGAGACAG
TGTACAGCTTCTGCGAACAGGTCGGCCTACCGACCACGCTTGCCGACATCGGCCTCGAAAACGCCGACCCTGCGAAACTG
ATGCCGGCTGCCGAAAAAGCCTGTGCTCCGAGCGAATGCATCCACAACGAAGCCGGAACAGTCACGCCAAACAAAGTGCT
GCACGCCATGCTTGCCGCCGACGCTTACGGCCAGCAGCGCAGGCGAAAGGTCTGA

Upstream 100 bases:

>100_bases
CGAACAAACCCGTCTTTCGCAAGCAATTCAACTTGTGTACTTTACACGATCCTAAACATTCGAAGACAGCCACGTAATCT
GTCTTAAATCGTATCCACCT

Downstream 100 bases:

>100_bases
TTCCCCCTCGCCGAAAGCCGCAGCTTTTGACTTATCCCGGCGGATTCGCTACTATTCTTACACGGCCTGACCTTTCAAGC
CAACCGGGCAGACCAGCCCT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MLNKVFFPGKYIQGAGALDELPELIRSFGKCGLLLGSPTVLETILPDSGLDVQSGLLNTELFHGECSATELSRLEKVIRE
RKSDVLVGMGGGKTIDAAKVAADRAGVPVIIVPTIASTDAPCSGCAVVYSDDGAFESVAYQKSNPAAVLVDLNIIAKAPA
RFLVAGMGDALATWFEARSCSATKSPNSCGGLSTLTGLSLAQLCYDTLLQYGNAARIAAEQQVITPALEHIVEANILLSG
VGFESGGLASAHSIHNGLTALPETHRFYHGEKVAFGTLAGLHLTDADPAEIETVYSFCEQVGLPTTLADIGLENADPAKL
MPAAEKACAPSECIHNEAGTVTPNKVLHAMLAADAYGQQRRRKV

Sequences:

>Translated_364_residues
MLNKVFFPGKYIQGAGALDELPELIRSFGKCGLLLGSPTVLETILPDSGLDVQSGLLNTELFHGECSATELSRLEKVIRE
RKSDVLVGMGGGKTIDAAKVAADRAGVPVIIVPTIASTDAPCSGCAVVYSDDGAFESVAYQKSNPAAVLVDLNIIAKAPA
RFLVAGMGDALATWFEARSCSATKSPNSCGGLSTLTGLSLAQLCYDTLLQYGNAARIAAEQQVITPALEHIVEANILLSG
VGFESGGLASAHSIHNGLTALPETHRFYHGEKVAFGTLAGLHLTDADPAEIETVYSFCEQVGLPTTLADIGLENADPAKL
MPAAEKACAPSECIHNEAGTVTPNKVLHAMLAADAYGQQRRRKV
>Mature_364_residues
MLNKVFFPGKYIQGAGALDELPELIRSFGKCGLLLGSPTVLETILPDSGLDVQSGLLNTELFHGECSATELSRLEKVIRE
RKSDVLVGMGGGKTIDAAKVAADRAGVPVIIVPTIASTDAPCSGCAVVYSDDGAFESVAYQKSNPAAVLVDLNIIAKAPA
RFLVAGMGDALATWFEARSCSATKSPNSCGGLSTLTGLSLAQLCYDTLLQYGNAARIAAEQQVITPALEHIVEANILLSG
VGFESGGLASAHSIHNGLTALPETHRFYHGEKVAFGTLAGLHLTDADPAEIETVYSFCEQVGLPTTLADIGLENADPAKL
MPAAEKACAPSECIHNEAGTVTPNKVLHAMLAADAYGQQRRRKV

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions [H]

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=359, Percent_Identity=50.974930362117, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1786815, Length=304, Percent_Identity=33.8815789473684, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 38063; Mature: 38063

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKVFFPGKYIQGAGALDELPELIRSFGKCGLLLGSPTVLETILPDSGLDVQSGLLNTE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCHHHCCCCCC
LFHGECSATELSRLEKVIRERKSDVLVGMGGGKTIDAAKVAADRAGVPVIIVPTIASTDA
EECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHCCCCCEEEEECCCCCCC
PCSGCAVVYSDDGAFESVAYQKSNPAAVLVDLNIIAKAPARFLVAGMGDALATWFEARSC
CCCCCEEEECCCCCHHHHEECCCCCCEEEEEEHHHHHCCHHHHHHCCCHHHHHHHHHHCC
SATKSPNSCGGLSTLTGLSLAQLCYDTLLQYGNAARIAAEQQVITPALEHIVEANILLSG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEE
VGFESGGLASAHSIHNGLTALPETHRFYHGEKVAFGTLAGLHLTDADPAEIETVYSFCEQ
CCCCCCCCCHHHHHHCCCCCCCCHHHHHCCCEEEEEEEECEEECCCCHHHHHHHHHHHHH
VGLPTTLADIGLENADPAKLMPAAEKACAPSECIHNEAGTVTPNKVLHAMLAADAYGQQR
HCCCHHHHHCCCCCCCCHHHCCHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
RRKV
HCCC
>Mature Secondary Structure
MLNKVFFPGKYIQGAGALDELPELIRSFGKCGLLLGSPTVLETILPDSGLDVQSGLLNTE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCHHHCCCCCC
LFHGECSATELSRLEKVIRERKSDVLVGMGGGKTIDAAKVAADRAGVPVIIVPTIASTDA
EECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHCCCCCEEEEECCCCCCC
PCSGCAVVYSDDGAFESVAYQKSNPAAVLVDLNIIAKAPARFLVAGMGDALATWFEARSC
CCCCCEEEECCCCCHHHHEECCCCCCEEEEEEHHHHHCCHHHHHHCCCHHHHHHHHHHCC
SATKSPNSCGGLSTLTGLSLAQLCYDTLLQYGNAARIAAEQQVITPALEHIVEANILLSG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEE
VGFESGGLASAHSIHNGLTALPETHRFYHGEKVAFGTLAGLHLTDADPAEIETVYSFCEQ
CCCCCCCCCHHHHHHCCCCCCCCHHHHHCCCEEEEEEEECEEECCCCHHHHHHHHHHHHH
VGLPTTLADIGLENADPAKLMPAAEKACAPSECIHNEAGTVTPNKVLHAMLAADAYGQQR
HCCCHHHHHCCCCCCCCHHHCCHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
RRKV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12193646 [H]