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The map label for this gene is apbE [H]

Identifier: 193212694

GI number: 193212694

Start: 1146453

End: 1147334

Strand: Direct

Name: apbE [H]

Synonym: Cpar_1039

Alternate gene names: 193212694

Gene position: 1146453-1147334 (Clockwise)

Preceding gene: 193212693

Following gene: 193212695

Centisome position: 50.08

GC content: 58.62

Gene sequence:

>882_bases
ATGCAACGGTTTGAATTCAGGGCGATGGGCAGTGCGTGCGAGATTGTGCTCGCAGGAGTCGACAAAAAGGAGTCGAAGAT
TCTGGCCGCGCTTGCCATGAAAGATGTCGCCCGGATCGAGCGGAAGTTTTCCCGTTACCAGCCGGAAAGCGTAATCTCGA
AGATCAATGCACAAGCCGGACTCGGCTTGACAGTGTGCGACGAGGAGACATCGGCGTTGATCGACTATGCTGATGCCGTG
TATCGCAGCAGCGGAGGACTCTTCGACGTGACCTCCGGCGTGCTGCGAAAAGCGTGGGATTTCGACCGCGCTGAAGTGCC
ATCGCAAAAGATGCTCTTTGAGTTGCTGAAGCTCGTCGGCTGGGAGCATGTGGAGCGAGAGGGAAGTGTTGTGCGATTGC
CAGAGGTGGGAATGCAGCTCGACTTCGGCGGTATCGGCAAGGAGTATGCCGCCGATGCGGCAGCGGAGCTTCTGAATGAG
CAGGGTGTCCGGCACGGCTATGTGAATCTGGGCGGTGACCTCCGCATCATCGGCCCGAAGCCCAGCGGTGAGCCGTGGAC
AATCGGCATTCGCGATCCGCGCAAGCCAGGCAGCATGATCGCCTCGATTCCGGTCAGTTCCGGTGCCATCGCCACGAGCG
GCGATTACGAGCGCTTTTTCGAGTTGGCGGGGCAGCGCTACTGCCACATCATCAACCCGAAGAGTGGCTGGCCGGTGAGC
TTCTGGCGCTCGGTCACGGTGCTCGCCCCACTGGCAACAACGGCGGGCAGTTGCGCAACCATCGCGATGCTGCTCGAAAA
ACAGGGCGTGACCTATCTGAAAAAGTCCGGCTTCAACTATCTGGCAATCGATCAAAACGGCAAGCTGTATCATAACCATT
GA

Upstream 100 bases:

>100_bases
TCGGGCATCCCATCCTTCAGGTTCAGAAACATCCAGCTCGGATTGTCGCGCAAGCTGTGATGCTTAAAAAACGTCTGCAT
TGATGTAATTTATTGTCCGT

Downstream 100 bases:

>100_bases
ACAACCATCATGATCAAACAAGTAACCCCTCGACGTCTGATTTCGGTTTTCACGGTGCTCCTTATTCTGCTCATGAGGAG
CACCACTGGCCTTGCCGCTG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MQRFEFRAMGSACEIVLAGVDKKESKILAALAMKDVARIERKFSRYQPESVISKINAQAGLGLTVCDEETSALIDYADAV
YRSSGGLFDVTSGVLRKAWDFDRAEVPSQKMLFELLKLVGWEHVEREGSVVRLPEVGMQLDFGGIGKEYAADAAAELLNE
QGVRHGYVNLGGDLRIIGPKPSGEPWTIGIRDPRKPGSMIASIPVSSGAIATSGDYERFFELAGQRYCHIINPKSGWPVS
FWRSVTVLAPLATTAGSCATIAMLLEKQGVTYLKKSGFNYLAIDQNGKLYHNH

Sequences:

>Translated_293_residues
MQRFEFRAMGSACEIVLAGVDKKESKILAALAMKDVARIERKFSRYQPESVISKINAQAGLGLTVCDEETSALIDYADAV
YRSSGGLFDVTSGVLRKAWDFDRAEVPSQKMLFELLKLVGWEHVEREGSVVRLPEVGMQLDFGGIGKEYAADAAAELLNE
QGVRHGYVNLGGDLRIIGPKPSGEPWTIGIRDPRKPGSMIASIPVSSGAIATSGDYERFFELAGQRYCHIINPKSGWPVS
FWRSVTVLAPLATTAGSCATIAMLLEKQGVTYLKKSGFNYLAIDQNGKLYHNH
>Mature_293_residues
MQRFEFRAMGSACEIVLAGVDKKESKILAALAMKDVARIERKFSRYQPESVISKINAQAGLGLTVCDEETSALIDYADAV
YRSSGGLFDVTSGVLRKAWDFDRAEVPSQKMLFELLKLVGWEHVEREGSVVRLPEVGMQLDFGGIGKEYAADAAAELLNE
QGVRHGYVNLGGDLRIIGPKPSGEPWTIGIRDPRKPGSMIASIPVSSGAIATSGDYERFFELAGQRYCHIINPKSGWPVS
FWRSVTVLAPLATTAGSCATIAMLLEKQGVTYLKKSGFNYLAIDQNGKLYHNH

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=300, Percent_Identity=25.6666666666667, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 32065; Mature: 32065

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFEFRAMGSACEIVLAGVDKKESKILAALAMKDVARIERKFSRYQPESVISKINAQAG
CCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
LGLTVCDEETSALIDYADAVYRSSGGLFDVTSGVLRKAWDFDRAEVPSQKMLFELLKLVG
CCEEEECCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHC
WEHVEREGSVVRLPEVGMQLDFGGIGKEYAADAAAELLNEQGVRHGYVNLGGDLRIIGPK
HHHHHCCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCC
PSGEPWTIGIRDPRKPGSMIASIPVSSGAIATSGDYERFFELAGQRYCHIINPKSGWPVS
CCCCCEEEECCCCCCCCCEEEECCCCCCCEECCCCHHHHHHHCCCCEEEEECCCCCCCHH
FWRSVTVLAPLATTAGSCATIAMLLEKQGVTYLKKSGFNYLAIDQNGKLYHNH
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCCEECCC
>Mature Secondary Structure
MQRFEFRAMGSACEIVLAGVDKKESKILAALAMKDVARIERKFSRYQPESVISKINAQAG
CCCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
LGLTVCDEETSALIDYADAVYRSSGGLFDVTSGVLRKAWDFDRAEVPSQKMLFELLKLVG
CCEEEECCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHC
WEHVEREGSVVRLPEVGMQLDFGGIGKEYAADAAAELLNEQGVRHGYVNLGGDLRIIGPK
HHHHHCCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCC
PSGEPWTIGIRDPRKPGSMIASIPVSSGAIATSGDYERFFELAGQRYCHIINPKSGWPVS
CCCCCEEEECCCCCCCCCEEEECCCCCCCEECCCCHHHHHHHCCCCEEEEECCCCCCCHH
FWRSVTVLAPLATTAGSCATIAMLLEKQGVTYLKKSGFNYLAIDQNGKLYHNH
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]