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The map label for this gene is dsbD [H]

Identifier: 193212695

GI number: 193212695

Start: 1147344

End: 1149209

Strand: Direct

Name: dsbD [H]

Synonym: Cpar_1040

Alternate gene names: 193212695

Gene position: 1147344-1149209 (Clockwise)

Preceding gene: 193212694

Following gene: 193212696

Centisome position: 50.12

GC content: 56.11

Gene sequence:

>1866_bases
ATGATCAAACAAGTAACCCCTCGACGTCTGATTTCGGTTTTCACGGTGCTCCTTATTCTGCTCATGAGGAGCACCACTGG
CCTTGCCGCTGATTTTCTCGATCCTGAACAGGCATTCAAAATCAGTGCGGAACTGACCGGCAACAAAACCATCGCCTTGC
ACTGGAACATCGCCGAGTCATACAAGCTTTACAAGAACCAGATGACGGTCGACGTGACCAGCGGAACGGCCACCCTCGGT
AACCCGTCGTTTCCCGAGGGTATTCTTTTCACCGATCCGACAACTGGCGAAAAAGAGATCATTTATCATGATAAACTGAC
GGTCGAAGTACCGATCAAAGAGGCCTTGGCACCATTTACCGTAAGCGTCGGCTACCAAGGCTGTTCGGAGGACGGGTTGT
GTTATCCTCCGATTACGACAGACTTCCGTGTCGATCCATCAAAACCGGGTGTTTTATCTATTGTGACTGAGCCGGATGGC
AGCGGTTCGGCCGGGTTATTACCGGCAACAGCTCAAGTCCAGCCTGAGACAGTCACACCTGCTTCCACGGCATCGAAAGA
ATCGGGCGGCCAGAACGATCTTTCGCTCGCAAAATCCACGCTCGAAAGCGGAAGCTGGTGGAAGATTTCCGCTGCGTTCC
TGCTCTTCGGACTGCTGCTGTCCTTCACGCCCTGCGTGCTGCCGATGGTGCCGATTCTCTCCTCGATCATCGTCGGAGAA
GGGGAGAGCACCAAAATGAAGAGCTTCCTCATGGCGGTAGCCTACTGCCTCGGCATGGCACTGGTGTACACCTCGCTCGG
CGTGGCCGCGGGACTTGCCGGGGAAGGGCTTGCCGGAGCGCTCCAGAAACCCTGGGTGCTGGCGCTGTTCAGCCTGCTGC
TGGTTGCACTGTCACTCTCGATGTTCGACGTCTACGAGCTTCAGCTGCCCTCTTCGCTGCAAACGAGCCTGAACAAAACC
ACCGGCAAGCTCAAGGGCGGTAAATTCGCTGGCGTGTTCCTGATGGGCGCCATTTCTGCGCTGATCGTCGGCCCCTGCGT
GGCCGCACCGCTGGCCGGAACGCTGGTCTATATCAGCCAGACGAAGGATGTGTTCATCGGCGGTCTGGCGCTCTTTTCGA
TGGCGATGGGCATGAGCGTGCCGCTGCTACTTATCGGCCTTTCCGCCGGAAGCTTGCTTCCGAAAGCCGGAGCCTGGATG
ATCGGCGTCAAATACGTGTTCGGTCTGTTGCTGCTTGCCGTTGCTATCTGGATGGTAACGCCCGTGCTACCGCCACAGGC
TCTGATGGTCGCGTGGGGTACGCTCGGTATCCTCTGCGCGGTCTTCGCCGGAGTCTTCGGCCCACCCGCCGAAAAACTCA
CCATCGGCGGCAAATTCAAAAAAGCACTCGGTCTGGTGCTCTTCATCATCGGCGTCATGGAACTGGTAGGAGCGGCATCT
GGCGGTACCGATGCGCTGAAACCGCTCTCGGGATTCCACAGTGTTTCCGGCTCGGTTGCCACAAAGACAGAGCACCTCAC
CTTCAAGCGAGTCCACTCCATCGACGAACTCGATCGTGAACTGCAAGCCTCCGCAGGCAACCCCGTCATGCTTGATTTTT
ACGCCGATTGGTGCGTTTCGTGCAAGGAGCTGGAAAAGTTCACCTTCAGCGATCCCAAGGTGCAGCAGGCGCTTGCAAAC
GTCACACTGCTGCAGGTCGATGTGACGGCAAACAGTGAAGACGACAAAGCTCTGATGAAACGTTTCAGCCTGTTTGGCCC
GCCCGGAATCATCTTTTTCGACAAGTCAGGCAACGAGCAATCAGACAACAGGATTATTGGATTTGTCGAGGCTCAGGAAT
TCCTGAGACACTTGGAGAGATTATGA

Upstream 100 bases:

>100_bases
GCTCGAAAAACAGGGCGTGACCTATCTGAAAAAGTCCGGCTTCAACTATCTGGCAATCGATCAAAACGGCAAGCTGTATC
ATAACCATTGAACAACCATC

Downstream 100 bases:

>100_bases
GTGATGAATTGAAGAAGAGTTGACGAAATGGAGGATCAGGAATGATCAGGGGGCGGGCTTATTTGTCCGCCTTTTTTGTT
TTACGAGCTTGATCGCGATC

Product: Protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MIKQVTPRRLISVFTVLLILLMRSTTGLAADFLDPEQAFKISAELTGNKTIALHWNIAESYKLYKNQMTVDVTSGTATLG
NPSFPEGILFTDPTTGEKEIIYHDKLTVEVPIKEALAPFTVSVGYQGCSEDGLCYPPITTDFRVDPSKPGVLSIVTEPDG
SGSAGLLPATAQVQPETVTPASTASKESGGQNDLSLAKSTLESGSWWKISAAFLLFGLLLSFTPCVLPMVPILSSIIVGE
GESTKMKSFLMAVAYCLGMALVYTSLGVAAGLAGEGLAGALQKPWVLALFSLLLVALSLSMFDVYELQLPSSLQTSLNKT
TGKLKGGKFAGVFLMGAISALIVGPCVAAPLAGTLVYISQTKDVFIGGLALFSMAMGMSVPLLLIGLSAGSLLPKAGAWM
IGVKYVFGLLLLAVAIWMVTPVLPPQALMVAWGTLGILCAVFAGVFGPPAEKLTIGGKFKKALGLVLFIIGVMELVGAAS
GGTDALKPLSGFHSVSGSVATKTEHLTFKRVHSIDELDRELQASAGNPVMLDFYADWCVSCKELEKFTFSDPKVQQALAN
VTLLQVDVTANSEDDKALMKRFSLFGPPGIIFFDKSGNEQSDNRIIGFVEAQEFLRHLERL

Sequences:

>Translated_621_residues
MIKQVTPRRLISVFTVLLILLMRSTTGLAADFLDPEQAFKISAELTGNKTIALHWNIAESYKLYKNQMTVDVTSGTATLG
NPSFPEGILFTDPTTGEKEIIYHDKLTVEVPIKEALAPFTVSVGYQGCSEDGLCYPPITTDFRVDPSKPGVLSIVTEPDG
SGSAGLLPATAQVQPETVTPASTASKESGGQNDLSLAKSTLESGSWWKISAAFLLFGLLLSFTPCVLPMVPILSSIIVGE
GESTKMKSFLMAVAYCLGMALVYTSLGVAAGLAGEGLAGALQKPWVLALFSLLLVALSLSMFDVYELQLPSSLQTSLNKT
TGKLKGGKFAGVFLMGAISALIVGPCVAAPLAGTLVYISQTKDVFIGGLALFSMAMGMSVPLLLIGLSAGSLLPKAGAWM
IGVKYVFGLLLLAVAIWMVTPVLPPQALMVAWGTLGILCAVFAGVFGPPAEKLTIGGKFKKALGLVLFIIGVMELVGAAS
GGTDALKPLSGFHSVSGSVATKTEHLTFKRVHSIDELDRELQASAGNPVMLDFYADWCVSCKELEKFTFSDPKVQQALAN
VTLLQVDVTANSEDDKALMKRFSLFGPPGIIFFDKSGNEQSDNRIIGFVEAQEFLRHLERL
>Mature_621_residues
MIKQVTPRRLISVFTVLLILLMRSTTGLAADFLDPEQAFKISAELTGNKTIALHWNIAESYKLYKNQMTVDVTSGTATLG
NPSFPEGILFTDPTTGEKEIIYHDKLTVEVPIKEALAPFTVSVGYQGCSEDGLCYPPITTDFRVDPSKPGVLSIVTEPDG
SGSAGLLPATAQVQPETVTPASTASKESGGQNDLSLAKSTLESGSWWKISAAFLLFGLLLSFTPCVLPMVPILSSIIVGE
GESTKMKSFLMAVAYCLGMALVYTSLGVAAGLAGEGLAGALQKPWVLALFSLLLVALSLSMFDVYELQLPSSLQTSLNKT
TGKLKGGKFAGVFLMGAISALIVGPCVAAPLAGTLVYISQTKDVFIGGLALFSMAMGMSVPLLLIGLSAGSLLPKAGAWM
IGVKYVFGLLLLAVAIWMVTPVLPPQALMVAWGTLGILCAVFAGVFGPPAEKLTIGGKFKKALGLVLFIIGVMELVGAAS
GGTDALKPLSGFHSVSGSVATKTEHLTFKRVHSIDELDRELQASAGNPVMLDFYADWCVSCKELEKFTFSDPKVQQALAN
VTLLQVDVTANSEDDKALMKRFSLFGPPGIIFFDKSGNEQSDNRIIGFVEAQEFLRHLERL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=617, Percent_Identity=36.3047001620746, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 65913; Mature: 65913

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQVTPRRLISVFTVLLILLMRSTTGLAADFLDPEQAFKISAELTGNKTIALHWNIAES
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHEEEEEEECCCEEEEEEECHHHH
YKLYKNQMTVDVTSGTATLGNPSFPEGILFTDPTTGEKEIIYHDKLTVEVPIKEALAPFT
HHHHHCCEEEEEECCCEECCCCCCCCCEEECCCCCCCCEEEEECCEEEEECHHHCCCCEE
VSVGYQGCSEDGLCYPPITTDFRVDPSKPGVLSIVTEPDGSGSAGLLPATAQVQPETVTP
EEECCCCCCCCCEECCCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
ASTASKESGGQNDLSLAKSTLESGSWWKISAAFLLFGLLLSFTPCVLPMVPILSSIIVGE
CCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GESTKMKSFLMAVAYCLGMALVYTSLGVAAGLAGEGLAGALQKPWVLALFSLLLVALSLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHH
MFDVYELQLPSSLQTSLNKTTGKLKGGKFAGVFLMGAISALIVGPCVAAPLAGTLVYISQ
HHHHEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
TKDVFIGGLALFSMAMGMSVPLLLIGLSAGSLLPKAGAWMIGVKYVFGLLLLAVAIWMVT
CCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PVLPPQALMVAWGTLGILCAVFAGVFGPPAEKLTIGGKFKKALGLVLFIIGVMELVGAAS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
GGTDALKPLSGFHSVSGSVATKTEHLTFKRVHSIDELDRELQASAGNPVMLDFYADWCVS
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
CKELEKFTFSDPKVQQALANVTLLQVDVTANSEDDKALMKRFSLFGPPGIIFFDKSGNEQ
HHHHHHHCCCCHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCC
SDNRIIGFVEAQEFLRHLERL
CCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MIKQVTPRRLISVFTVLLILLMRSTTGLAADFLDPEQAFKISAELTGNKTIALHWNIAES
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHEEEEEEECCCEEEEEEECHHHH
YKLYKNQMTVDVTSGTATLGNPSFPEGILFTDPTTGEKEIIYHDKLTVEVPIKEALAPFT
HHHHHCCEEEEEECCCEECCCCCCCCCEEECCCCCCCCEEEEECCEEEEECHHHCCCCEE
VSVGYQGCSEDGLCYPPITTDFRVDPSKPGVLSIVTEPDGSGSAGLLPATAQVQPETVTP
EEECCCCCCCCCEECCCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
ASTASKESGGQNDLSLAKSTLESGSWWKISAAFLLFGLLLSFTPCVLPMVPILSSIIVGE
CCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GESTKMKSFLMAVAYCLGMALVYTSLGVAAGLAGEGLAGALQKPWVLALFSLLLVALSLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHH
MFDVYELQLPSSLQTSLNKTTGKLKGGKFAGVFLMGAISALIVGPCVAAPLAGTLVYISQ
HHHHEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
TKDVFIGGLALFSMAMGMSVPLLLIGLSAGSLLPKAGAWMIGVKYVFGLLLLAVAIWMVT
CCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PVLPPQALMVAWGTLGILCAVFAGVFGPPAEKLTIGGKFKKALGLVLFIIGVMELVGAAS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCC
GGTDALKPLSGFHSVSGSVATKTEHLTFKRVHSIDELDRELQASAGNPVMLDFYADWCVS
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
CKELEKFTFSDPKVQQALANVTLLQVDVTANSEDDKALMKRFSLFGPPGIIFFDKSGNEQ
HHHHHHHCCCCHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCC
SDNRIIGFVEAQEFLRHLERL
CCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]